Effects of anxiety state on N400 event-related brain potential response to unexpected semantic stimuli.

Emotional states can influence how people use meaningful context to make predictions about what comes next. To measure whether state anxiety influences such prediction, we used the N400 event-related brain potential (ERP) response to semantic stimuli, whose amplitude is smaller (less negative) when the stimulus is more predicted based on preceding context. Participants (n = 28) were randomized to one of two groups, who underwent either an "anxious-uncertainty" procedure previously shown to increase anxiety, or a control procedure. Both before and after this procedure, participants' ERPs were recorded while they viewed category definitions (e.g., "a type of fruit"), each followed by a target word that was either a high-typicality category exemplar ("apple"), low-typicality exemplar ("cherry"), or non-exemplar ("clamp") of the category. Participants' task was to respond by pressing one of two buttons to indicate whether the target represented a member of the category. As expected, based on previous work, overall, N400 amplitudes were largest (most negative) in response to non-exemplars, intermediate to low-typicality exemplars, and smallest to high-typicality exemplars. N400 amplitudes were larger to non-exemplars after the anxious-uncertainty procedure than after the control procedure. N400 amplitudes to both types of exemplars did not differ after the anxious-uncertainty procedure versus the control procedure. The results are consistent with participants devoting more neural resources to processing contextually unexpected items under anxious states, rather than anxiety facilitating processing of expected items.

Health appeal appraisal and memory in older adults: the effects of goal and valence framing.

Relative to younger adults, older adults have a preference and memory advantage for appeals framed to focus on emotion goals (e.g., loving or caring) or positive outcomes (e.g., benefits of health behaviors). Here we examined whether combining goal (emotion vs. future) and valence framing (positive vs. negative) could optimize older adults' appraisal and memory for health appeals. Sixty younger (ages 18-29) and 60 older (ages 64-87) adults viewed, rated and recalled one of the four versions of a health pamphlet, each with a unique combination of goal and valence framing. The results showed a memory advantage for pamphlets focusing on emotion over future goals in both age groups. Older adults also showed a more favorable appraisal and a weak memory advantage for the positively- and emotion-framed pamphlet, relative to younger adults. Thus combining goal and valence framing could optimize the effectiveness of older adults' health appeal communication..

Feeling safe: Judgements of safety and anxiety as a function of worry and intolerance of uncertainty.

Safety perspectives of generalized anxiety disorder (GAD) propose that safety perception is critical to regulating anxiety. Reduced safety processing may contribute to persistent worry and anxiety that extend to recognizably safe contexts. We explored whether individuals higher in worry and intolerance of uncertainty (IU), central characteristics of GAD, display poorer recognition and use of safety cues, and whether safety perception is related to anxiety. One hundred and eighty-two adults were presented with unfolding potentially threatening scenarios, half of which contained safety information. Participants rated how safe and anxiety-provoking each scenario was as they received new information, as well as overall. Using multilevel modeling, results showed that individuals higher in worry and IU recognize safety information and use it to appraise the safety of a situation. A moderate correlation between safety and anxiety ratings, and inconsistent correspondence between ratings of safety and anxiety, suggest this relationship is complicated by additional factors. Individuals higher in worry and IU may have difficulty accepting their safety appraisals in order to inhibit their anxiety. The implications of the findings and future avenues of research are discussed.

Religiosity is associated with less prediction of the typical: An event-related brain potential study.

Why are some people more religious than others? According to one hypothesis, people who strongly seek definitive explanations for situations with incomplete information are more likely to be religious. According to a different hypothesis, individuals with smaller "prediction error" responses to unexpected stimuli are more likely to discount evidence contradicting religious beliefs, predisposing them to maintain such beliefs. We sought neurophysiological evidence for these hypotheses using the N400 event-related potential (ERP), which is smaller to more contextually expected stimuli, reflecting prediction of probable completions for meaningful situations. We recorded ERPs from participants viewing category definitions followed by high-typicality category exemplar (HTE), low-typicality exemplar (LTE), or non-exemplar (NE) words. As expected, N400s were largest for NEs, intermediate for LTEs, and smallest for HTEs. Religiosity correlated with smaller N400 amplitude differences between HTEs and both LTEs and NEs. Less strong prediction of probable stimuli based on prior information may predispose to religiosity.