ABSTRACT
A brazilian housewife, descendant of japanese (both parents), 37 years aged, affected with Vogt-Koyanagi's syndrome (uveitis, dysacousia, alopecia, madarosis, poliosis, vitiligo) was treated with prednisone. During the course and at the end of the treatment an almost complete regression of alopecia, poliosis, madarosis and a total involution of the dysacousia could be observed, meanwhile the vitiligo and the sequels of uveitis remained unchanged. Taking into account that Vogt-Koyanagi's syndrome is susceptible of expontaneous involution, no definitive conclusion about the efficiency of therapeutic agent may be drawn in this singular case. However, it must be considered as valid the possibility of a favourable action of a systemic treatment with corticosteroides in the initial stages of the disease chiefly for preventing its more harmful consequences, i.e. deafness and blindness.
Subject(s)
Prednisone/therapeutic use , Uveitis/drug therapy , Uveomeningoencephalitic Syndrome/drug therapy , Adult , Drug Evaluation , Female , Humans , Pigmentation Disorders/drug therapy , TabletsABSTRACT
Two patients affected with vitiligo showed achromic lesions in areas of skin apparently normal submitted to the action of external traumatic agents. In the first case the striate linear lesion might be attributed to the excoriation due to pruritus determined by scabies. In the second one an angular lesion in both feet was strictly limited to the areas exposed to the straps of sandals.
