ABSTRACT
Se presentan los hallazgos clínicos y de laboratorio en una joven con artritis reumatoide juvenil tratada con esteroides, la cual presentó un cuadro infeccioso terminal caracterizado por fiebre, insuficiencia respiratoria, ictericia y arritmia ventricular. La "biopsia hepática postmortem" permitió comprobar una hepatitis aguda por citomegalovirus. Se comentan aspectos diversos de esta modalidad de hepatitis viral descrita por primera vez en Venezuela
Subject(s)
Adolescent , Humans , Female , Arthritis, Juvenile/complications , Cytomegalovirus/pathogenicity , Hepatitis, Viral, Human/complicationsABSTRACT
The epidemiology of arteriosclerotic hearth disease has changed form a strictly biological concept of medical ecology to a broader one which considers the life forms of the host in addition to the interaction between the host and his natural environment. Thus, consideration must be given to other parameters besides the traditional ones of sex, age, etc., and an ad hoc methodology must be developed which will be applicable to the largest possible number of areas and circumstances
To that end, a study was made to relate mortality due to tuberculosis and arteriosclerotic disease of the heart to social factors. Material prepared by the Inter-American Investigation of Mortality was used for the purpose. (It is based on the absolute numbers of weighted deaths distributed by cause, occupation, sex, and 10-year age groups, ranging from 15 to 74 years)
Ten of the twelve cities studied under this survey were located in Latin America, and the other two were San Francisco in the United States, and Bristol in the United Kingdom. The following social classes were established: A) leading professions and business; B) lesser professions and business, as well as skilled non-manual workers; and C) skilled manual workers, and semi-skilled and unskilled workers. In all 12 cities, of the deaths of males, 13 per cent were from occupations under Class A, 20 per cent under Class B, and 67 per cent under Class C. ...(AU)
Subject(s)
Coronary Artery Disease , Social Class , Latin AmericaABSTRACT
Epidemiology is no longer concerned with only the medical factors involved in the interaction of host and environment. As now conceived, it deals with a more complex network of interrelationships, formed by the host, his natural environment, and-as an added factor-his way of life. This modern approach requires the development of a special methodology applicable to the greatest possible number of areas and circumstances.
Subject(s)
Coronary Artery Disease , Social Class , Latin AmericaABSTRACT
Before mortality data can serve as reliable bases for international epidemiological studies there are difficulties of terminology, nosology and language to be overcome. The Inter-American Investigation of Mortality is a large-scale collaborative research project specifically designed to circumvent these obstacles and to yield death rates by causes which will be as accurate and comparable as possible. Twelve widely separated cities are participating in the Investigation by following standard procedures. Approximately 4,000 deaths at ages 15-74 years are being individually studies over a two-year period in each city. All available data relevant to establishing the nature of the fatal conditions are systematically assembled by a local team. Central review including referral to two medical referees ensures assignment of cause of death in accordance with established international practice. By providing accurate and comparable age-specific death rates by causes (with particular emphasis on heart disease and cancer) for highly diverse populations the Investigation will indicate those areas where further epidemiological research may be profitably developed. In addition, information of value will be obtained for disease prevention, for administration of medical services and for the improvement of health statistics
