ABSTRACT
The paper reports two cases of transitory hyperphosphatasemia in two siblings of 13 and 29 months without modifications of the liver, kidney or bones. Laboratory data are given for hepatic and renal function and for the calcium/phosphorus metabolism. The paper underlines the observation of rotavirus and the consequent clinical symptoms in the two subjects. The hypothesised etiopathogenesis of transitory idiopathic hyperphosphatasemia is referred to a viral mechanism, and to rotavirus in particular.
Subject(s)
Alkaline Phosphatase/blood , Clinical Enzyme Tests , Rotavirus Infections/complications , Child, Preschool , Humans , Infant , Male , Rotavirus Infections/diagnosis , Time FactorsABSTRACT
Screening methods for nitrosamines in beer were studied by 15 collaborators. Collaborators studied 4 extraction techniques and 2 calculation procedures. All methods showed acceptable recoveries and no significant differences between methods. Based on accuracy, simplicity and speed, the Celite extraction with internal standard calculation is recommended. Fifteen collaborators also studied a distillation confirmatory method compared with a direct extraction with dichloromethane. Because the former gives an extract more suitable for mass spectrometric confirmation of nitrosamines, it is the recommended reference method. The screening and confirmatory methods have been adopted official first action.
