ABSTRACT
Dermatological findings for patients with human T lymphotropic virus type 1(HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) were investigated and were compared with dermatological findings for a control group. Only xerosis, cutaneous candidiasis, and palmar erythema were significantly associated with HAM/TSP. Histopathological patterns of cutaneous lymphoma were seen in 25% of 32 patients who underwent biopsy, and, thus, the cutaneous alterations in HAM/TSP can be classified into nonspecific lesions, infectious lesions, immune-inflammatory-mediated lesions, and premalignant or malignant lesions.
Subject(s)
HTLV-I Infections/complications , Human T-lymphotropic virus 1 , Paraparesis, Tropical Spastic/complications , Spinal Cord Diseases/complications , Adult , Age Distribution , Female , Humans , Male , Middle Aged , Skin DiseasesABSTRACT
A total of 148 cats with a clinical and mycologic diagnosis of sporotrichosis and 84 apparently healthy cats with domiciliary contact with the affected animals were studied. Sporothrix schenckii was isolated from 148 (n = 148; 100%) clinical samples of cutaneous lesion (biopsy, swab or aspiration of purulent secretion), 47 (n = 71; 66.2%) nasal cavities, 33 (n = 79; 41.8%) oral cavities, and 15 (n = 38; 39.5%) nails of cats with sporotrichosis. Histopathological examination revealed yeast-like structures in 50 (n = 70; 71.4%) of the biopsies studied. S. schenckii was isolated from the blood culture of one cat (n = 5, 20%) with the disseminated cutaneous form of the disease. On another occasion, the fungus was isolated from the testis of one (n = 7; 14.3%) of the animals submitted to sterilization. In the group of cats with domiciliary contacts, 3 (n = 84; 3.57%) oral swabs showed positive cultures. Isolation of S. schenckii from different clinical specimens during both the clinical and preclinical phase reinforces the zoonotic potential of feline sporotrichosis.
Subject(s)
Cat Diseases/microbiology , Sporothrix/isolation & purification , Sporotrichosis/veterinary , Animals , Brazil , Cats , Female , Male , Mouth Mucosa/microbiology , Nails/microbiology , Nasal Cavity/microbiology , Skin/microbiology , Sporotrichosis/microbiologyABSTRACT
We present the case of a 15-year-old patient infected with HTLV-1 who developed a cutaneous T-cell lymphoma, confirmed by histopathological and immunohistochemical examination, as well as clinically and hematologically confirmed leukemia. The patient died 3 months after initial presentation of the disease. The rarity of the disease in this age group justifies the present report
Subject(s)
Humans , Female , Adolescent , Leukemia-Lymphoma, Adult T-Cell , Skin Neoplasms , Brazil , Fatal Outcome , Leukemia-Lymphoma, Adult T-Cell , Prion Diseases , Skin NeoplasmsABSTRACT
Cutaneous biopsies (n = 94) obtained from 88 patients with American tegumentary leishmaniasis were studied by conventional and immunohistochemical techniques...
Subject(s)
Animals , Humans , Male , Female , Adult , Middle Aged , Rabbits , Antigens, Protozoan/analysis , Cicatrix/parasitology , Leishmaniasis, Cutaneous/pathology , Antibodies, Protozoan , Biopsy , Case-Control Studies , Cytoplasm/enzymology , Cytoplasm/immunology , Immunoenzyme Techniques , Immunoglobulin A/immunology , Immunoglobulin G/immunology , Immunoglobulin M/immunology , Immunohistochemistry , Leishmania braziliensis/isolation & purification , Leishmaniasis, Cutaneous/immunology , Leishmaniasis, Cutaneous/parasitology , Macrophages/enzymology , Skin TestsABSTRACT
O presente artigo visa a discussão da nefropatia relacionada à infecção pelo vírus da imunodeficiência adquirida (HIV) em seus aspectos epidemiológicos, clínicos e histopatológicos, ressaltando a importância e necessidade de seu melhor conhecimento e do aprofundamento do diagnóstico e terapêutica, com o objetivo de alcançar a diminuição da morbiletalidade relacionada à doença
Subject(s)
Humans , AIDS-Associated Nephropathy/epidemiology , AIDS-Associated Nephropathy/physiopathology , AIDS-Associated Nephropathy/therapy , Glomerulonephritis, Membranoproliferative/epidemiology , Glomerulonephritis, Membranoproliferative/physiopathologyABSTRACT
During the period from 1987 to 1998, 13 cases of human sporotrichosis were recorded at the Research Center Evandro Chagas Hospital (CPqHEC) in Rio de Janeiro. Two of these patients related scratch by a sick cat. During the subsequent period from July 1998 to July 2000, 66 human, 117 cats and 7 dogs with sporotrichosis were diagnosed at the CPqHEC. Fifty-two humans (78.8 percent) reported contact with cats with sporotrichosis, and 31 (47 percent) of them reporting a history of a scratch or bite. This epidemic, unprecedented in the literature, involving cats, dogs and human beings may have started insidiously before 1998
Subject(s)
Humans , Animals , Male , Female , Child , Adolescent , Adult , Middle Aged , Cats , Dogs , Communicable Diseases, Emerging/epidemiology , Sporotrichosis/epidemiology , Brazil/epidemiologyABSTRACT
Apos diagnostico, em 1992, de 2 pacientes eliminando esporos de microsporideos, o presente estudo foi realizado com o objetivo de determinar a ocorrencia destes organismos em pacientes HIV-positivos com diarreia cronica sem etiologia definida. O grupo estudado era constituido de 13 pacientes acompanhados no Hospital Evandro Chagas, IOC, FIOCRUZ. Amostras fecais de cada paciente foram examinadas pelos metodos de rotina, alem de colaracoes especiais para a pesquisa de Cryptosporidium e de microsporideos. Esporos de microsporideos foram observados nas fezes de 6 (46,1 por cento) dos 13 pacientes. Em 2 a confirmacao foi feita por biopsia de jejuno, pela observacao de formas evolutivas intracelulares do parasito...
