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1.
Ophthalmologe ; 109(7): 710-2, 2012 Jul.
Article in German | MEDLINE | ID: mdl-22532040

ABSTRACT

The emergency consultation of a female patient revealed a left-sided prolapse of the eyeball with visual loss. The patient had fallen against an object hitting the left eye 40 min prior to the consultation. Motility of the eye was severely restricted and retinoscopy was impossible due to a corneal edema. The pupil was moderately dilated and non-reactive. The ocular pressure was 50 mmHg. Spontaneous repositioning was unsuccessful and an immediate lateral canthotomy was performed. The follow-up control showed that the patient had recovered good visual acuity with a reduction of intraocular pressure and pain. The latest findings were uneventful.


Subject(s)
Exophthalmos/etiology , Exophthalmos/surgery , Eye Injuries/complications , Eye Injuries/surgery , Ophthalmologic Surgical Procedures/methods , Wounds, Nonpenetrating/complications , Wounds, Nonpenetrating/surgery , Adult , Exophthalmos/diagnosis , Eye Injuries/diagnosis , Female , Humans , Treatment Outcome , Wounds, Nonpenetrating/diagnosis
2.
Mol Vis ; 18: 390-402, 2012.
Article in English | MEDLINE | ID: mdl-22355250

ABSTRACT

Gingko biloba has been used for hundreds of years to treat various disorders such as asthma, vertigo, fatigue and, tinnitus or circulatory problems. Two of the main extracts are EGb761 and LI 1370. Most pharmacological, toxicological and clinical studies have focused on the neuroprotective value of these two main extracts. Neuroprotection is a rapidly expanding area of research. This area is of particular interest due to the fact that it represents a new avenue of therapy for a frustrating disease that may progress despite optimal treatment. One such disease is glaucoma.Glaucoma leads to the loss of retinal ganglion cells and their axons but also to tissue remodelling which involves both the optic nerve head and the retina. In the retina the astrocytes get activated. In addition, the optic nerve gets thinner and the cells of the lateral geniculate ganglion disappear partially. On average, ocular blood flow (OBF) is reduced in glaucoma patients in various tissues of the eye. Increased intraocular pressure (IOP) is a major risk factor for glaucomatous damage. Nevertheless, there is little doubt that other risk factors besides IOP are involved. One such risk factor is a primary vascular dysregulation (PVD) occurring in patients with a disturbed autoregulation, another risk factor is oxidative stress.


Subject(s)
Ginkgo biloba , Glaucoma/drug therapy , Low Tension Glaucoma/drug therapy , Phytotherapy , Animals , Chemotherapy, Adjuvant , Eye/blood supply , Eye/drug effects , Ginkgo biloba/adverse effects , Humans , Intraocular Pressure/drug effects , Mice , Optic Nerve Diseases/drug therapy , Oxidative Stress/drug effects , Phytotherapy/adverse effects , Plant Extracts/adverse effects , Plant Extracts/therapeutic use
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