1.
Pol J Vet Sci
; 24(4): 607-610, 2021 Dec.
Article
in English
| MEDLINE
| ID: mdl-35179844
ABSTRACT
In recent years there have been a growing number of reports on applying viruses in oncological treatment. In the present study, we demonstrated for the first time that animal virus EHV-1 productively replicates in the human adenocarcinoma cell line (A549) without the need for adaptation. Real-time PCR analysis and immunofluorescence assay showed that EHV-1 could infect and causes lysis of human lung cancer cells. According to our results, we can assume that EHV-1 has oncolytic potential.