ABSTRACT
The combination of ectrodactyly, ectodermal dysplasia, and cleft lip with or without cleft palate (EEC syndrome) is a rare type of congenital anomaly. It usually occurs as an autosomal-dominant trait or less commonly in a sporadic form. In this complex, multiple congenital anomaly syndrome, any of the three cardinal manifestations may present with variable expressions.
Subject(s)
Cleft Palate/epidemiology , Ectodermal Dysplasia/diagnosis , Ectodermal Dysplasia/epidemiology , Fingers/abnormalities , Syndactyly/epidemiology , Adult , Humans , Male , SyndromeABSTRACT
A 24-year-old female presented with a firm, hyperpigmented, and gradually enlarging, tender, solitary dermal nodule of non-traumatic origin over the right suprascapular region. The lesion was extending into the subcutaneous tissue. She was otherwise normal. There was no calcification on X-ray. Biopsy revealed numerous large pleomorphic fibroblasts in a mucoid ground substance diagnostic of nodular fasciitis. No recurrence was noticed after surgical excision. This case is reported because of its rarity in the Indian medical literature.
ABSTRACT
A case of Squamous cell Carcinoma arising in discoid lupus erythematosus of 10 years duration is described. The constant exposure to U-V rays in sunlight, in addition to the chronic hypoxidosis in the scar resulting from chronic discoid iupus erythematosus, is assumed to induce malignant degeneration.
