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Cancer Immunol Immunother ; 16(3): 170-4, 1984.
Article in English | MEDLINE | ID: mdl-6561069

ABSTRACT

We have analysed the influence of human malignant, inflammatory and infectious disease on the capacity of peripheral lymphocytes to mediate antibody-dependent haemolysis. The application of an enzyme-like kinetic model for measurement of maximal cytotoxic function has permitted reproducible and sensitive determinations of the K-cell function. The results show that malignant disease is associated with enhancement of ADCC capacity.


Subject(s)
Killer Cells, Natural/immunology , Neoplasms/immunology , Antibody-Dependent Cell Cytotoxicity , Female , Humans , Male , Middle Aged , Sex Factors
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