ABSTRACT
24 cases of salinomycin poisoning in horses occurring recently in Silesia are discussed. All of these horses, used for riding-purposes, were fed with concentrate containing 61 mg/kg salinomycin as faulty prepared by the manufacturer. Each horse received approximately two to three kilograms of this forage. All horses developed severe clinical signs of intoxication. Despite therapy eight horses died within three to six days. Ten others became recumbent and had to be euthanased. Only six horses survived. Clinical and laboratory examinations were performed and are discussed. Laboratory examination of blood included red blood cell count, haematocrit, concentration of haemoglobin, enzyme activities of ASAT, ALAT and AP, also levels of urea, creatinine, sodium, potassium, magnesium, calcium and inorganic phosphor. Blood gas was also analysed. The dominating laboratory results were very high enzyme levels and alkalosis. The most characteristic clinical change appeared as paralysis of the hindlimbs.
Subject(s)
Anti-Bacterial Agents/poisoning , Horse Diseases , Poisoning/veterinary , Pyrans/poisoning , Animal Feed , Animals , Anti-Bacterial Agents/administration & dosage , Electrolytes/blood , Erythrocyte Count , Euthanasia , Germany , Hematocrit , Hemoglobins/analysis , Horses , Male , Poisoning/blood , Poland , Pyrans/administration & dosageABSTRACT
Sweat secretion was analyzed quantitatively and qualitatively in 20 horses after a 5 min. gallop at 450 m/min. The analysis revealed concentration of proteins 63.3 +/- 6.47 g/l, mainly albumins, a high level of sodium 254.43 +/- 62.84 mM/,l chloride 268.68 +/- 98.46 mM/l, potassium 98.95 +/- 49.62 mM/l and calcium 4.14 +/- 0.8 mM/l. A dependence was found between the protein concentration in serum and its quantity in sweat and between the level of potassium in sweat and its loss from the cells within a range 8.6 to 25.8 mM/l. The hypertonic horse sweat protects organism for excessive water loss, the loss taking place by imperceptible evaporation. The loss of body weight amounted to 5.64 +/- 2.36 kg and the loss with the sweat was only 1.56 kg. Besides its thermoregulation function, the sweat ensures a proper effort homeostasis-isoosmic and isoionic status.
