ABSTRACT
PURPOSE: The recent rapid increase of hadron therapy applications requires the development of high performance, reliable in vivo models for preclinical research on the biological effects of high linear energy transfer (LET) particle radiation. AIM: The aim of this paper was to test the relative biological effectiveness (RBE) of the zebrafish embryo system at two neutron facilities. MATERIAL AND METHODS: Series of viable zebrafish embryos at 24-hour post-fertilization (hpf) were exposed to single fraction, whole-body, photon and neutron (reactor fission neutrons (
Subject(s)
Embryo, Nonmammalian/radiation effects , Linear Energy Transfer , Zebrafish/embryology , Animals , Neutrons/adverse effects , Photons/adverse effects , Relative Biological Effectiveness , Survival AnalysisABSTRACT
Monte Carlo simulations using MCNP6.1 were performed to study the effect of neutron activation in Ar/CO2 neutron detector counting gas. A general MCNP model was built and validated with simple analytical calculations. Simulations and calculations agree that only the 40Ar activation can have a considerable effect. It was shown that neither the prompt gamma intensity from the 40Ar neutron capture nor the produced 41Ar activity have an impact in terms of gamma dose rate around the detector and background level.
ABSTRACT
A self-absorption correction factor is required for the determination of the radioactive isotope concentration in sediment samples at the low-energy region. A simplified technique for this correction factor for a well-type HP germanium detector is described. This correction is especially important when the ratio between the sample density and reference sample density (rho(sa.)/rho(re)) is greater than approximately 1.4.