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1.
J Perinatol ; 36(11): 1001-1007, 2016 11.
Article in English | MEDLINE | ID: mdl-27583386

ABSTRACT

OBJECTIVE: Nurses provide parental support and education in the neonatal intensive care unit (NICU), but it is unknown if satisfaction and expectations about nursing care differ between racial groups. STUDY DESIGN: A prospective cohort was constructed of families with a premature infant presenting to primary care between 1 January 2010 and 1 January 2013 (N=249, 52% white, 42% black). Responses to questions about satisfaction with the NICU were analyzed in ATLAS.ti using the standard qualitative methodology. RESULTS: One hundred and twenty (48%) parents commented on nursing. Fifty-seven percent of the comments were positive, with black parents more negative (58%) compared with white parents (33%). Black parents were most dissatisfied with how nurses supported them, wanting compassionate and respectful communication. White parents were most dissatisfied with inconsistent nursing care and lack of education about their child. CONCLUSIONS: Racial differences were found in satisfaction and expectations with neonatal nursing care. Accounting for these differences will improve parental engagement during the NICU stay.


Subject(s)
Neonatal Nursing/organization & administration , Nurse-Patient Relations , Nursing Care/psychology , Parents/psychology , Patient Satisfaction , Adolescent , Adult , Black or African American/psychology , Culturally Competent Care , Empathy , Female , Humans , Infant, Newborn , Infant, Premature , Intensive Care Units, Neonatal/organization & administration , Male , Prospective Studies , Surveys and Questionnaires , White People/psychology , Young Adult
2.
J Perinatol ; 33(11): 893-8, 2013 Nov.
Article in English | MEDLINE | ID: mdl-23660581

ABSTRACT

OBJECTIVE: The objective of this study was to longitudinally evaluate the neurodevelopmental (ND) outcome in congenital diaphragmatic hernia (CDH) survivors during the first 3 years of life. STUDY DESIGN: The study cohort consists of 47 CDH survivors that were enrolled in our prospective, follow-up program between July 2004 and September 2010, and underwent serial ND evaluations during the first 3 years of life. ND outcomes were evaluated using the Bayley Scales of Infant Development (BSID)-II or BSID-III. Persistent ND impairment was defined as a score that remained 79 for the cognitive, language and psychomotor domains at the most recent follow-up visit compared with the first assessment. RESULT: The median age at first and last evaluation was 8 (range, 5 to 15) and 29 (range, 23 to 36) months, respectively. During the follow-up, ND scores improved to average in 17%, remained average in 60%, remained delayed in 10%, improved from severely delayed to mildly delayed in 2% and deteriorated from average to delayed in 15%. Motor scores improved to average in 26%, remained average in 55%, remained delayed in 8% and improved from severely delayed to mildly delayed in 11%. Intrathoracic liver position (P=0.004), preterm delivery (P=0.03), supplemental O2 requirement at day of life 30 (P=0.007), age at discharge (P=0.03), periventricular leukomalacia (PVL; P=0.004) and initial neuromuscular hypotonicity (P=0.01) were associated with persistent motor delays. No relationship was found between patient's characteristics and the risk of persistent cognitive and language delays. CONCLUSION: (1) The majority of children with CDH are functioning in the average range by early preschool age, (2) most children who had early delays showed improvement in their ND outcome, (3) children showing delays in all the three domains were the least likely to show improvement and (4) CDH severity appears to be predictive of persistent psychomotor delays.


Subject(s)
Developmental Disabilities/etiology , Hernias, Diaphragmatic, Congenital , Psychomotor Performance/physiology , Child, Preschool , Female , Hernia, Diaphragmatic/physiopathology , Humans , Infant , Male , Prospective Studies
3.
AACN Clin Issues ; 9(1): 11-24; quiz 143-4, 1998 Feb.
Article in English | MEDLINE | ID: mdl-9505569

ABSTRACT

Changes in neonatal care have resulted in an increased survival rate among low birth weight infants. Because their neurologic system is immature, these infants are vulnerable to neurologic injury. Major and minor neurodevelopmental consequences can result. Most preterm infants survive without serious difficulties; however, the lower the birth weight, the higher the likelihood that problems will occur. Numerous factors can increase a preterm infant's risk for disease and impairment, and the neonatal nurse can perform a significant role in minimizing this risk.


Subject(s)
Developmental Disabilities/etiology , Infant, Low Birth Weight/growth & development , Infant, Premature/growth & development , Nervous System/growth & development , Developmental Disabilities/prevention & control , Humans , Infant, Newborn , Intensive Care Units, Neonatal , Neonatal Nursing , Risk Factors
6.
Pediatrics ; 96(5 Pt 1): 907-13, 1995 Nov.
Article in English | MEDLINE | ID: mdl-7478834

ABSTRACT

OBJECTIVE: Although extracorporeal membrane oxygenation (ECMO) has been responsible for the improved survival of infants with cardiorespiratory failure, its use over the last decade has raised concern as to the health of the survivors and the severity of neurodevelopmental sequelae. Though infants meeting ECMO criteria have a variety of reasons prompting the use of this therapy, most studies to date have simply reported outcome on the entire population that has survived without regard to the original nature of the child's illness. The purpose of this study was to determine the type and extent of health-related problems and neurodevelopmental sequelae in infants requiring ECMO therapy and the association of these findings with the infants' primary diagnosis. METHODS: Eighty-two neonates required ECMO therapy between May 1990 and December 1993. The most common diagnosis prompting ECMO therapy included 26% with meconium aspiration syndrome, 34% with congenital diaphragmatic hernia (CDH), 16% with persistence of the fetal circulation, and 9% with sepsis. Information concerning the hospital course was obtained through chart review, and the infants were seen at 6 and 12 months of age for medical and neurodevelopmental follow-up. Data were analyzed using descriptive statistics and Fisher's exact test, t-tests, and analysis of variance where appropriate. Assessment of hospital course and discharge data focused on the four main diagnostic groups, whereas follow-up data were further limited to the two most frequently encountered groups (meconium aspiration syndrome and CDH). RESULTS: Overall survival was 79%. Significant differences in survival were noted based on primary diagnostic category. Those with CDH fared the worst, with an overall survival rate of 68% and a more complicated hospital course with a longer duration of ECMO. At discharge, the CDH group demonstrated a greater incidence of bronchopulmonary dysplasia, gastroesophageal reflux, feeding dysfunction, and hypotonia. No significant differences were noted in the incidence of intraventricular hemorrhage, cerebral infarction, extra-axial fluid collection, or seizures. Hearing loss was uncommon. During the first year of life, although no differences were noted in growth rate, infants in the CDH group continued to experience a higher incidence of gastroesophageal reflux (43%) and feeding dysfunction, with 36% of this group requiring tube feedings for nourishment. Although 40% of the entire ECMO population was diagnosed with bronchopulmonary dysplasia before initial discharge, by 1 year of age, 50% of those with CDH versus 17% of those with meconium aspiration syndrome continued to be clinically symptomatic. Although the ECMO population as a whole scored in the normal range developmentally, CDH infants had significantly lower motor and slightly lower cognitive scores at 1 year of age. Despite finding abnormal muscle tone in a high percentage of the entire ECMO population at discharge, most demonstrated resolution by 1 year of age. Of the CDH infants, however, 75% continued to evidence some degree of hypotonicity, which affected acquisition and quality of gross motor skills. CONCLUSION: Despite the impact that ECMO has had on the survival of infants with severe respiratory failure, the efficacy of ECMO cannot be assessed accurately without an analysis of the extent and morbidity in the surviving population. Most centers are reporting relatively low morbidity for the entire ECMO population. However, upon separating this population into primary diagnostic categories, we found that the CDH population encountered a greater number of neurodevelopmental, respiratory, and feeding abnormalities during the first year of life. The reasons for these differences are unclear but may be related to the severity of the primary illness itself or the variables associated with prolonged ECMO therapy. Stratifying outcome by primary diagnosis gives the health care provider more information to improve


Subject(s)
Developmental Disabilities/etiology , Extracorporeal Membrane Oxygenation , Infant, Newborn, Diseases , Respiratory Insufficiency/therapy , Bronchopulmonary Dysplasia/epidemiology , Developmental Disabilities/epidemiology , Enteral Nutrition , Female , Follow-Up Studies , Gastroesophageal Reflux/epidemiology , Gastroesophageal Reflux/etiology , Hernia, Diaphragmatic/complications , Hernia, Diaphragmatic/mortality , Humans , Infant, Newborn , Infant, Newborn, Diseases/mortality , Male , Meconium Aspiration Syndrome/complications , Meconium Aspiration Syndrome/mortality , Nervous System Diseases/epidemiology , Nervous System Diseases/etiology , Persistent Fetal Circulation Syndrome/complications , Persistent Fetal Circulation Syndrome/mortality , Respiratory Insufficiency/etiology , Respiratory Insufficiency/mortality , Sepsis/complications , Sepsis/mortality , Survival Rate , Treatment Outcome
7.
Pediatr Neurol ; 12(4): 294-304, 1995 May.
Article in English | MEDLINE | ID: mdl-7546003

ABSTRACT

Cranial magnetic resonance imaging (MRI) of 31 newborn infants treated with venoarterial cardiopulmonary bypass for severe but reversible respiratory failure, revealed major focal parenchymal lesions in 7 of 31 infants (23%) and demonstrated abnormal enlargement of extra-axial and ventricular cerebrospinal fluid spaces in 16 of 31 (51%). No preferential left versus right lateralization of focal injury was observed in conjunction with right common carotid artery and jugular vein ligation. No statistically significant relationships were found between major brain lesions on MRI scans and the clinical characteristics of the pre-extracorporeal membrane oxygenation (ECMO), ECMO, and post-ECMO course. Major focal brain lesions were significantly associated with an asymmetric cerebrovascular response to carotid ligation of the right versus left middle cerebral arteries as detected by magnetic resonance angiography (P < .05). Enlarged cerebrospinal fluid spaces were not significantly related to the presence of parenchymal MRI lesions, but were associated with lower Bayley neurodevelopmental scores for mental (MDI) and psychomotor evaluations (PDI) at 6 and 12 months (P < .05). It is concluded that asymmetries of cerebral vascular adaptation detected by magnetic resonance angiography after ECMO may be associated with major brain lesions revealed by MRI. Thereafter, the presence of enlarged cerebrospinal fluid spaces on MRI is associated with a poor shortterm developmental outcome.


Subject(s)
Brain/pathology , Cerebrovascular Disorders/complications , Extracorporeal Membrane Oxygenation , Magnetic Resonance Angiography , Magnetic Resonance Imaging , Respiratory Insufficiency/therapy , Brain/growth & development , Critical Illness , Humans , Infant, Newborn , Prospective Studies , Respiratory Insufficiency/complications , Respiratory Insufficiency/pathology , Treatment Outcome
8.
J Pediatr Surg ; 30(1): 10-5, 1995 Jan.
Article in English | MEDLINE | ID: mdl-7722808

ABSTRACT

Congenital diaphragmatic hernia (CDH) has been associated with a high mortality rate. The purposes of this study were to determine the impact of extracorporeal membrane oxygenation (ECMO) on the survival of infants with CDH and to document the sequelae and 1-year neurodevelopmental outcome for CDH infants who required ECMO. Thirty neonates with CDH were admitted between May 7, 1990 and October 1, 1992. Twenty required ECMO and were enrolled in our neonatal follow-up program. Information about the infants' neonatal course was obtained from chart review, and the infants were seen at 3, 6, and 12 months of age for medical and neurodevelopmental follow-up. Primary diaphragmatic repair was performed in 13 infants. Five required Goretex graft reconstruction (GGR), and two did not have repair. Sixteen (80%) of the 20 infants who required ECMO survived. The overall survival rate increased from 31% (10 of 32) in the 5 years previous to the start of the ECMO program to 63% (19 of 30) since then (P = .01). The most common sequelae noted by the time of discharge included gastroesophageal reflux (GER; 81%), the need for tube feeding (69%), and chronic lung disease (CLD; 62%). At 1 year of age, mean cognitive skills were average (87 +/- 23) and motor skills were borderline (75 +/- 24) according to the Bayley Scales of Infant Development. Hypotonia was present in 10 of 13 patients.(ABSTRACT TRUNCATED AT 250 WORDS)


Subject(s)
Arteriovenous Shunt, Surgical , Extracorporeal Membrane Oxygenation , Hernia, Diaphragmatic/therapy , Prostheses and Implants , Algorithms , Child Development/physiology , Combined Modality Therapy , Follow-Up Studies , Gastroesophageal Reflux/etiology , Gastroesophageal Reflux/physiopathology , Hernia, Diaphragmatic/mortality , Hernia, Diaphragmatic/physiopathology , Hernias, Diaphragmatic, Congenital , Humans , Infant , Infant, Newborn , Length of Stay , Morbidity , Polytetrafluoroethylene , Postoperative Care , Postoperative Complications/etiology , Postoperative Complications/physiopathology , Retrospective Studies , Survival Rate , Time Factors , Treatment Outcome
9.
Urol Int ; 46(1): 119-20, 1991.
Article in English | MEDLINE | ID: mdl-2024363

ABSTRACT

A 35-year-old white male presented with erectile dysfunction and areflexic bladder secondary to an intrathecal paraganglioma of the cauda equina. Erectile dysfunction has not been emphasized as a component of the cauda equina syndrome.


Subject(s)
Cauda Equina , Erectile Dysfunction/etiology , Paraganglioma/complications , Peripheral Nervous System Neoplasms/complications , Adult , Humans , Male , Nerve Compression Syndromes/etiology , Penis/innervation
10.
Urol Int ; 46(1): 58-60, 1991.
Article in English | MEDLINE | ID: mdl-2024374

ABSTRACT

Clinical correlations have been made with the applied anatomy of the infradiphragmatic urethra. The entire urethra was removed en bloc and the infradiaphragmatic urethra was carefully dissected with metallic sounds in situ. The urethra immediately distal to the urogenital diaphragm is devoid of any corporal tissue anteriorly and constitutes the 'bare area' tha can easily be injured during rigid urethral instrumentation.


Subject(s)
Urethra/anatomy & histology , Aged , Humans , Male , Middle Aged , Reference Values
11.
Addict Behav ; 11(4): 431-4, 1986.
Article in English | MEDLINE | ID: mdl-3812052

ABSTRACT

Forty-two male cigarette smokers, age 18 to 44, were randomly assigned to high-nicotine, low-nicotine, or control groups in a study relating cigarette smoking to sexual response. Subjects watched erotic film segments while their penile diameters, heart rates, and finger pulse amplitudes were continuously recorded by a polygraph. Subjects in the smoking groups smoked relatively high-nicotine (.9 mg) or very low-nicotine (.002 mg) cigarettes prior to watching the last two films, while control subjects ate candy. Smoking two high-nicotine cigarettes in immediate succession significantly decreased the rate of penile diameter change relative to the other conditions. These effects were not seen after a single cigarette was smoked. High-nicotine cigarettes caused significantly more vasoconstriction and heart rate increase than did low-nicotine cigarettes, which did not differ from control conditions.


Subject(s)
Nicotine/pharmacology , Penile Erection/drug effects , Smoking , Adolescent , Adult , Erectile Dysfunction/chemically induced , Fingers/blood supply , Heart Rate/drug effects , Humans , Male , Pulse/drug effects , Reaction Time/drug effects , Vasoconstriction/drug effects
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