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1.
Arq Neuropsiquiatr ; 60(3-B): 779-87, 2002 Sep.
Article in Portuguese | MEDLINE | ID: mdl-12364949

ABSTRACT

The objective of this study was to evaluate the utility of interictal brain SPECT in localizing the epileptogenic focus in a population of patients of Epilepsy Clinic of Hospital Universitário Clementino Fraga Filho (HUCFF/UFRJ), with medically refractory temporal lobe epilepsy (TLE) and normal computed tomography (CT) scans, studying the correlation between SPECT, electroencephalogram (EEG) and, in 11 cases, brain magnetic resonance imaging (MRI), and to compare the results to the other six literature series. Twelve (52.2%) patients presented abnormal SPECT. Among these, five (41.6% of abnormal SPECTs) presented unilateral SPECT changes at the same side of EEG (hypoperfusion in four and hyperperfusion in one), three (25% of abnormal SPECTs) presented bilateral hypoperfusion and bilateral EEG changes too, and four (33.3%) presented unilateral hypoperfusion and bilateral EEG changes. The statistical analysis was based on fuzzy logic. The correlation index among SPECT X EEG, SPECT X MRI and SPECT X EEG X MRI were highly significant, with significance levels at 0.01, p < 0.0005 and trust interval at 99% in all correlations. The correlation studies between the series presented similar results.


Subject(s)
Epilepsy, Temporal Lobe/diagnostic imaging , Tomography, Emission-Computed, Single-Photon , Adolescent , Adult , Confidence Intervals , Cross-Sectional Studies , Electroencephalography , Female , Fuzzy Logic , Humans , Magnetic Resonance Spectroscopy , Male , Middle Aged , Prospective Studies
2.
Arq. neuropsiquiatr ; 60(3B): 779-787, Sept. 2002. tab, graf
Article in Portuguese | LILACS | ID: lil-325495

ABSTRACT

O objetivo desse estudo foi avaliar a utilidade do SPECT cerebral interictal na localizaçäo do foco epileptogênico em 23 pacientes do Ambulatório de Epilepsias do Hospital Universitário Clementino Fraga Filho (HUCFF/UFRJ), com epilepsia do lobo temporal (ELT) de difícil controle e tomografia computadorizada (TC) do crânio normal, estudando a correlaçäo entre SPECT interictal, eletrencefalograma (EEG) e, em 11 casos, ressonância magnética (RM) do crânio, e comparar os resultados com os de outras seis séries da literatura. Doze (52,2 por cento) pacientes apresentaram SPECT anormal. Entre esses, cinco (41,6 por cento dos SPECTs anormais) apresentaram alteraçäo unilateral ao SPECT do mesmo lado do EEG (hipoperfusäo em 4 e hiperperfusäo em 1), três (25 por cento dos SPECTs anormais) apresentaram hipoperfusäo bilateral ao SPECT e alteraçöes também bilaterais ao EEG e 4 (33,3 por cento dos SPECTs anormais) apresentaram hipoperfusäo unilateral ao SPECT e EEG bilateral. A análise estatística fundamentou-se na lógica fuzzy. Os índices de correlaçäo entre SPECT X EEG, SPECT X RM e SPECT X EEG X RM foram altamente significativos, com níveis de significância de 0,01, p < 0,0005 e intervalo de 99 por cento de confiança em todas as correlaçöes. Os estudos de correlaçäo entre as séries estudadas apresentaram resultados semelhantes entre si


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Adolescent , Epilepsy, Temporal Lobe , Tomography, Emission-Computed, Single-Photon , Confidence Intervals , Cross-Sectional Studies , Electroencephalography , Fuzzy Logic , Magnetic Resonance Spectroscopy , Prospective Studies
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