1.
Eur J Haematol
; 71(6): 464-5, 2003 Dec.
Article
in English
| MEDLINE
| ID: mdl-14703698
ABSTRACT
Severe cutaneous infections in leukaemic patients are difficult to treat and can rapidly become fatal. We report on a case of essential thrombocythemia evolved to a myelodysplastic syndrome and finally, to an overt myeloid leukaemia, refractory to chemotherapy. In the presence of a marked neutropenia, the patients developed a wide Staphylococcus epidermidis necrotising dermatitis. The diagnosis was made possible only by a skin biopsy culture and the antibiotic treatment, based on antimicrobial susceptibility tests, rapidly resolved the infection. In neutropenic patients, appropriate laboratory tests and treatment, can lead to recovery of life-threatening infections.
Subject(s)
Dermatitis/microbiology , Leukemia, Myeloid, Acute/complications , Neutropenia/complications , Staphylococcal Infections/etiology , Biopsy , Dermatitis/pathology , Humans , Male , Middle Aged , Myelodysplastic Syndromes/complications , Myelodysplastic Syndromes/diagnosis , Necrosis , Skin/pathology , Staphylococcal Infections/diagnosis , Staphylococcal Infections/drug therapy , Staphylococcus epidermidis , Thrombocythemia, Essential/complications , Thrombocythemia, Essential/diagnosis , Vancomycin/therapeutic use
2.
J Clin Oncol
; 19(5): 1570-2, 2001 Mar 01.
Article
in English
| MEDLINE
| ID: mdl-11230500