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J Assist Reprod Genet ; 12(3): 187-90, 1995 Mar.
Article in English | MEDLINE | ID: mdl-8520183

ABSTRACT

OBJECTIVES: To investigate the potential advantages of epidural anesthesia in an in vitro fertilization and embryo transfer program. STUDY DESIGN: Between January 1991 and December 1992, 148 infertile patients underwent transvaginal ultrasound guided oocyte retrieval. A total of 44 patients (group A) had 50 retrievals under epidural anesthesia, and 104 patients (group B, control group) 112 retrievals under intravenous sedation (propofol) with mask-assisted ventilation (nitrous oxide). RESULTS: In group A satisfactory anesthesia was achieved in 49 of the 50 cases (98%); one patient required additional intravenous administration of propofol owing to extreme anxiety. No complications were observed. Adversely, in group B nausea was observed in 16 cases (14%) and nausea and vomiting in 7 cases (6%). In group A the fertilization, cleavage and pregnancy rates were 67.2%, 92% and 20% respectively, while in group B the rates were 69.3%, 93% and 19.6% respectively; the differences are not statistically significant. CONCLUSIONS: Epidural anesthesia is an effective method for transvaginal oocyte retrieval but does not improve the treatment outcome as compared to an intravenous sedation with mask-assisted ventilation using propofol and nitrous oxide.


Subject(s)
Anesthesia, Epidural , Embryo Transfer , Fertilization in Vitro , Administration, Inhalation , Adult , Anesthesia, Epidural/adverse effects , Anesthesia, Obstetrical , Anesthetics, Intravenous , Embryonic and Fetal Development/physiology , Female , Humans , Injections, Intravenous , Nausea/chemically induced , Nitrous Oxide , Oocyte Donation/methods , Pregnancy , Pregnancy Rate , Propofol , Vomiting/chemically induced
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