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1.
Medicina (Kaunas) ; 57(8)2021 Jul 28.
Article in English | MEDLINE | ID: mdl-34440971

ABSTRACT

Background: Malignant gastric outlet obstruction (MGOD) is an extremely rare expression of advanced extra-gastrointestinal cancer, such as squamous cell carcinoma (SCC) of the cervix, and only sixcases are described in the literature.Because of the short life expectancyand the high surgical risk involving these patients, less invasive approaches have been developed over time, such asthe use of an enteral stent or less invasive surgical techniques (i.e., laparoscopic gastrojejunostomy). However, MGOD could make it difficult to perform an endoscopic retrograde cholangio-pancreatography (ERCP) for standard endoscopic drainage, so in this case a combined endoscopic-percutaneous technique may be performed. This article, therefore, aims to highlight the presence in the doctor's armamentarium of the "rendezvous technique", few case reports of whichare described in the literature, and, moreover, this article aims to underline the technique'sfeasibility. Case Presentation: The case is that of a 38-year-old woman who presented with MGOD three years after the diagnosis of SCC of the cervix, who successfully underwent the rendezvous technique with the resolution of duodenal obstruction. Endoscopic enteral stenting treatment with the placement of a metal stent (SEMSs) represents the mainstay of MGOD treatment compared withsurgery due to its lower morbidity, mortality, shorter hospitalization and earlier symptom relief. However, in patients with both duodenal and biliary obstruction, a combined endoscopic-percutaneous approach may be necessary because of the difficulty in passing the duodenal stricture or in accessing the papilla through the mesh of the duodenal SEMS. Conclusion: The rendezvous procedure is a technicallyfeasible and minimally invasive approach to the double stenting of biliary and duodenal strictures. It achieves the desired therapeutic result while avoiding the need to perform more invasive procedures that could have a negative impact on the patient'sprognosis.


Subject(s)
Cholestasis , Duodenal Obstruction , Gastric Outlet Obstruction , Adult , Cervix Uteri , Duodenal Obstruction/etiology , Duodenal Obstruction/surgery , Female , Gastric Outlet Obstruction/etiology , Gastric Outlet Obstruction/surgery , Humans , Retrospective Studies , Stents , Treatment Outcome
2.
BJR Case Rep ; 5(1): 20180055, 2019 Feb.
Article in English | MEDLINE | ID: mdl-31131128

ABSTRACT

The present case report describes imaging findings (CT and MRI features) of a primary malignant fibrous hystiocitoma, presenting as a dual stage lesion, completely exophytic along liver surface with surgical and histological correlations. Imaging characteristics suggested the nature of the lesion (mesenchymal) and the behavior (expansile growth pattern) which addressed surgeons to a conservative excision.

3.
Hum Vaccin Immunother ; 9(5): 1142-5, 2013 May.
Article in English | MEDLINE | ID: mdl-23370334

ABSTRACT

Cocoon is defined as a strategy to reduce the risk for transmission of pertussis to newborn infants by vaccinating household members including parents and siblings. Programmatic challenges make implementation of cocooning program complex. At the local health care unit "ASL Napoli 1 Centro," a one-year pilot project to evaluate the newborn contacts adherence to a cocoon strategy was started on May, 1st 2011. Healthcare providers (HCPs) offered for free a dTpa booster dose to newborns parents (mothers were immunized after delivery) and household contacts. Until June 30th, overall only 7 dTpa booster doses out of 261 newborns (2.6%) were administered for cocooning. Then, an improvement in communication strategy to the families was introduced by preparing specific information leaflets, increasing the HCPs devoted to the cocoon, and focusing the interaction with families during the visiting time at the maternity ward. Overall, 601 out of 762 (78,8%) contacted new mothers received dTpa booster. Cocoon high acceptance rates could be reached providing that proper communication tools and enough skilled HCPs were engaged in the interaction with the families. This report is, to our knowledge, the first to document successful implementation of pertussis cocooning in an Italian setting.


Subject(s)
Diphtheria-Tetanus-acellular Pertussis Vaccines/administration & dosage , Immunization, Secondary , Infant, Newborn, Diseases/prevention & control , Medication Adherence/statistics & numerical data , Whooping Cough/prevention & control , Whooping Cough/transmission , Adult , Fathers , Female , Health Education/methods , Humans , Infant , Infant, Newborn , Italy/epidemiology , Male , Mothers , Patient Acceptance of Health Care , Siblings
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