1.
Nature
; 281(5733): 650-5, 1979 Oct 25.
Article
in English
| MEDLINE
| ID: mdl-551285
ABSTRACT
Based on secondary structure prediction rules and model building a neutral artificial 34-residue polypeptide with potential nucleic acid-binding activity was synthesised. This peptide and its covalent dimer showed strong interaction with cytidine phosphates and single-stranded DNA. The dimer had considerable ribonuclease activity with high preference for cleavage at the 3'-end of C.