Riesgo cardiovascular y factores asociados en docentes de una institución universitaria / Cardiovascular risk and associated factors in university teachers

Objetivo El propósito de esta investigación se basó en identificar los factores que se asocian al riesgo cardiovascular en docentes de una universidad privada de Colombia. Materiales y métodos Se realizó un estudio descriptivo-transversal con fase analítica. Se realizó un muestreo probabilístico por fijación proporcional con docentes de tiempo completo, con un número de participantes de 104 docentes que cumplieron los criterios de inclusión. Resultados Con la participación de 55 mujeres (52,9%) y de 49 hombres (47,1%), se encontró relación estadísticamente significativa con la variable edad (p=0,001) con un OR 0,351; y con el índice de masa corporal (p=0,000) con un OR 6,071 estableciendo que existe seis veces la probabilidad de padecer una enfermedad cardiovascular por alteración del índice de masa corporal. Conclusión El índice de masa corporal es una variable constante en cuanto a la relación con la aparición de enfermedades cardiovasculares, lo cual refleja el estilo de vida de los individuos (AU)

Objective The aim of this study was to identify the factors associated with cardiovascular risk in teachers in a private university in Colombia. Materials and methods We performed a descriptive cross-sectional study with an analytical phase. Probabilistic sampling was performed by proportional fixation with 104 full-time teachers who met the inclusion criteria. Results There were 55 women (52.9%) and 49 men (47.1%). A statistically significant relationship was found with age (p=.001) with an OR 0.351, and with body mass index (p=.000) with an OR 6.071, establishing that altered body mass index conferred a 6-fold increased risk of cardiovascular disease. Conclusion Body mass index is a constant variable in terms of the relationship with the occurrence of cardiovascular disease, which reflects individuals’ lifestyle (AU)

[Cardiovascular risk and associated factors in university teachers]. / Riesgo cardiovascular y factores asociados en docentes de una institución universitaria.

OBJECTIVE: The aim of this study was to identify the factors associated with cardiovascular risk in teachers in a private university in Colombia. MATERIALS AND METHODS: We performed a descriptive cross-sectional study with an analytical phase. Probabilistic sampling was performed by proportional fixation with 104 full-time teachers who met the inclusion criteria. RESULTS: There were 55 women (52.9%) and 49 men (47.1%). A statistically significant relationship was found with age (p=.001) with an OR 0.351, and with body mass index (p=.000) with an OR 6.071, establishing that altered body mass index conferred a 6-fold increased risk of cardiovascular disease. CONCLUSION: Body mass index is a constant variable in terms of the relationship with the occurrence of cardiovascular disease, which reflects individuals' lifestyle.

Surgery with and without adjuvant radiotherapy is associated with similar survival in T4 colon cancer.

AIM: There is little evidence regarding the role of adjuvant radiotherapy for colon cancer. Despite this, national consensus guidelines recommend consideration of radiation for patients with T4 colon cancer. Large comparative studies may be beneficial in clarifying the potential benefit of postoperative radiation for this cohort. METHOD: We compared the overall survival between patients treated with surgery with and without adjuvant radiation using the National Cancer Database (NCDB) and the Surveillance, Epidemiology, and End Results Program (SEER), as well as disease-specific survival using SEER. Cox proportional hazards models and propensity score matching were used to adjust for relevant confounders. RESULTS: There were a total of 18 776 patients in the NCDB cohort and 9926 patients in the SEER cohort. After propensity score matching, there was no statistically significant difference in overall mortality between surgery with and without radiation in the NCDB [hazard ratio (HR) 1.11; 95% CI 0.93-1.31; P = 0.25] or in SEER (HR 1.20; 95% CI 0.84-1.72; P = 0.32). Additionally, using SEER, we found no statistically significant difference in disease-specific mortality between these two groups (HR 1.13; 95% CI 0.76-1.67; P = 0.54). CONCLUSION: Using the NCDB and SEER, we found no statistically significant difference in overall survival or disease-specific survival between patients treated with and without adjuvant radiation. Further studies should evaluate the impact of adjuvant radiotherapy on local control and prevention of recurrence-related morbidity in patients with T4 colon cancer.

Risk for interspecies transmission of zoonotic pathogens during poultry processing and pork production in Peru: A qualitative study.

Interspecies transmission of pathogens is an unfrequent but naturally occurring event and human activities may favour opportunities not previously reported. Reassortment of zoonotic pathogens like influenza A virus can result from these activities. Recently, swine and birds have played a central role as "mixing vessels" for epidemic and pandemic events related to strains like H1N1 and H5N1. Unsafe practices in poultry markets and swine farms can lead to interspecies transmission, favouring the emergence of novel strains. Thus, understanding practices that lead to interspecies interactions is crucial. This qualitative study aimed to evaluate poultry processing practices in formal and informal markets and the use of leftovers by swine farmers in three Peruvian cities: Lima (capital), Tumbes (coastal) and Tarapoto (jungle). We conducted 80 direct observations at formal and informal markets and interviewed 15 swine farmers. Processors slaughter and pluck chickens and vendors and/or processors eviscerate chickens. Food safety and hygiene practices were suboptimal or absent, although some heterogeneity was observed between cities and chicken vendors versus processors. Both vendors (76%) and processors (100%) sold the chicken viscera leftovers to swine farmers, representing the main source of chicken viscera for swine farms (53%). Swine farmers fed the chicken viscera to their swine. Chicken viscera cooking times varied widely and were insufficient in some cases. Non-abattoired poultry leads to the sale of poultry leftovers to small-scale swine farms, resulting in indirect but frequent interspecies contacts that can lead to interspecies transmission of bacterial pathogens or the reassortment of influenza A viruses. These interactions are exacerbated by suboptimal safety and hygiene conditions. People involved in these activities constitute an at-risk population who could play a central role in preventing the transmission of pathogens between species. Educational interventions on hygiene and food safety practices will be important for reducing the risk of interspecies influenza transmission.

ß-glucan enriched bath directly stimulates the wound healing process in common carp (Cyprinus carpio L.).

Wound healing is a complex and well-organized process in which physiological factors and immune mechanisms are involved. A number of different immune modulators have been found to enhance the non-specific defence system in vertebrates, among which ß-glucans are the most powerful and extensively investigated. The aim of the present study was to investigate the biological impact of two different commercially available ß glucan containing products on the wound healing process in carp. Throughout a two week experiment fish were kept either untreated (control), or in water supplemented with the two different types of ß-glucans. The wound healing process was monitored using a multispectral visualisation system. The correlation between wound closure and immune response was investigated by measuring the gene expression patterns of IL-1ß, IL-6 family member M17, IL-8 and Muc5b, and measurement of production of radical oxygen species. PAMPs/DAMPs stimulation caused by the wounding and or ß-glucans resulted in an inflammatory response by activating IL-1ß, IL-6 family member M17 and IL-8 and differences in the expression pattern were seen depending on stimuli. IL-1ß, IL-6 family member M17 and IL-8 were activated in all wounds regardless of treatment. Expression of all three interleukins was highly up regulated in control wounded muscle already at day 1 post-wounding and decreased at subsequent time-points. The reverse was the case with control wounded skin, where expression increased from day 1 through day 14. The results for the ß-glucan treated wounds were more complex. The images showed significantly faster wound contraction in both treated groups compared to the control. The obtained results clearly demonstrated that a ß glucan enriched bath promotes the closure of wounds in common carp and induce a local change in cytokine expression.

Fracture of the body of hamate associated with a fracture of the base of fourth metacarpal: A case report and review of literature of the last 20 years.

INTRODUCTION: Fractures of the carpal bones are often difficult to diagnose and treat due to the complex bone architecture of this region. Hamate fractures, particularly body fractures, are extremely uncommon. PRESENTATION OF CASE: We present a case of a coronal fracture of the hamate associated with a fracture of the base of the fourth metacarpal, which was treated by open reduction and internal fixation. DISCUSSION: Some of hamate body fractures are associated with other injuries like metacarpal fractures. Its diagnosis is difficult and requires a high clinical suspicion and a proper radiological examination. This fracture is a very rare lesion that can raise questions about their most adequate diagnostic and therapeutic approaches. CONCLUSION: After reviewing the literature, we conclude that there is a high rate of delay in the diagnosis of these lesions, probably due to their rarity and to the lack of radiological studies specifically targeting this region. Despite this, surgical treatment in its different modalities has been shown to have the best clinical and functional results.

Biodegradability and mechanical properties of starch films from Andean crops.

Different Andean crops were used to obtain starches not previously reported in literature as raw material for the production of biodegradable polymers. The twelve starches obtained were used to prepare biodegradable films by casting. Water and glycerol were used as plasticizers. The mechanical properties of the starch based films were assessed by means of tensile tests. Compost tests and FTIR tests were carried out to assess biodegradability of films. The results show that the mechanical properties (UTS, Young's modulus and elongation at break) of starch based films strongly depend on the starch source used for their production. We found that all the starch films prepared biodegrade following a three stage process and that the weight loss rate of all the starch based films tested was higher than the weight loss rate of the cellulose film used as control.