El propóleo una alternativa de todos los tiempos / Propolis: an alternative for all times

Se tiene conocimiento de que el empleo del propóleo en diversas afecciones data de miles de años. Fue utilizado por los egipcios, griegos y romanos. Actualmente el propóleo ha despertado un gran interés en científicos de todo el mundo, ya que ha demostrado una potente actividad biológica, desde el punto de vista terapéutico y nutricional. En nuestro país se han comprobado sus diferentes acciones farmacológicas, tales como: acción bactericida, antiviral, anestésica local y analgésica, inmunoestimulante, antioxidante, cicatrizante y regeneradora de tejidos, anticaries dentarias, antiinflamatoria, antitrombótica, antiulceroso. Resalta el hecho de que en nuestra provincia se usa principalmente en la estomatología. Basados en este argumento se realizó una búsqueda exhaustiva del tema para mostrar las consideraciones preventivas y terapéuticas actuales del propóleo y sus propiedades ventajosas de su uso, consultando 21 fuentes de las más actuales y fiables en Cuba y el resto del mundo(AU)

There is knowledge about the use of propolis to treat different diseases for thousand of years. Egyptians, Greeks and Romans made use of it. Currently propolis has increased scientific interest all over the world, due to its strong biological activity, from the therapeutic and nutritional point of view, providing evidence of pharmacological actions, such as: bactericide, antiviral, local anesthetic, analgesic, immune-stimulant, antioxidant, aids the formation of scar tissue and regenerates tissues; propolis can also avoid dental caries, it can be used as anti-inflammatory, antithrombotic and anti-ulcerous. In Pinar del Rio province it is mainly used in dentistry specialty. Supported on these good results, a far-reaching search about the topic was carried out in order to demonstrate the preventive and therapeutic applications of propolis and the advantages of its properties, reviewing 21 of the most current and reliable sources of information in Cuba and the rest of the world(AU)

[Frequency of imperforate anus and associated risk factors in patients with Down syndrome]. / Frecuencia del ano imperforado y factores de riesgo asociados en pacientes con síndrome de Down.

OBJECTIVES: To establish the frequency of imperforate anus (IA) in the population with Down syndrome (DS) and study the associated risk factors. METHODS: An observational clinical study case control type was performed. The patients were evaluated at the Unit of Medical Genetics, University of the Andes, from February 2006 to February 2011. The patients with DS and IA were compared with 20 DS without IA. Antecedents of parents were obtained. RESULTS: The frequency de IA in the population with DS was 4.79%. The presence of fever in the first trimester of gestation and the rural origin were associated as risk factors of AI in patients with DS [OR: 25.33 (IC 95% 2.07- 310.76; P = 0.009) and OR: 7.50 (IC 95% 1.09 - 51.52; P = 0.043), respectively]. The maternal age superior to 35 years presented a marginal significance (P = 0.048). CONCLUSIONS: These papers emphasize the high frequency of IA in patients with DS and recommend to investigate the prenatal and environmental risk factors that can increase the presence of this anorectal anomaly in the population with DS, in order to consider them in the programs of prevention of congenital pathologies.