Helminth Parasites of the Crane Hawk Geranospiza caerulescens (Vieillot) (Aves: Accipitridae) from Argentina, with the Description of a New Species of Parastrigea (Digenea: Strigeidae).

PURPOSE: The goal of this work was to increase the knowledge of the parasitic helminths of the Crane hawk, Geranospiza caerulescens. METHODS: Two specimens of the Crane hawk were captured in Formosa province, Argentina, their viscera were preserved in 10% formalin and examined in the laboratory. RESULTS: Helminthological analysis revealed the presence of six helminth taxa (one Trematoda, four Nematoda, and one Acanthocephala). The morphometric study of these helminths and its comparison with previous reports, allowed us to describe a new species of Parastrigea (Digenea: Strigeidae) and report new host-parasite associations and geographical records. Parastrigea labiata n. sp. is mainly characterized by having forebody not divided and two long trumpet-shaped projections of dorsal lip, which emerge through the opening. Five taxa, previously known, Synhimantus (Dispharynx) resticula, Synhimantus (Synhimantus) rectus, Microtetrameres sp., Porrocaecum sp. and Centrorhynchus sp. are briefly described. CONCLUSIONS: Previous parasitological studies on G. caerulescens were carried out on material collected between 1817 and 1955, and seven species of helminths were reported. In this study, the six taxa of helminths found constitute new host records, which shows the importance of contemporary studies about this host. All helminths found have heteroxenous life cycles and birds are infected by trophic transmission. Crane hawk's diet includes small vertebrates and to a lesser extent large arthropods. The finding of five helminth species that use invertebrates as intermediate hosts could indicate an important consumption of invertebrates. This research expands the helminthological inventory of Argentinean birds and the knowledge of the helminths of G. caerulescens.

Insertion Torque and Resonance Frequency Analysis in Tapered and Parallel Dental Implants.

Primary implant stability (PIS) is known to vary with recipient bone mass and density, dental implant design and surgical technique. The objective of this preliminary study was to compare rotational and lateral PIS of same-coronal-diameter conical and parallel implants, using insertion torque recorded with a dental implant motor set and implant stability quotient obtained from resonance frequency analysis (performed with both Osstell and Penguin systems) as measures of rotational and lateral stability, respectively. Additionally, the relationship between PIS and alveolar ridge width (ARW) was explored in both implant types. Sixty dental implants (30 tapered and 30 parallel) were randomly placed with a split-mouth design in 17 patients. Bone density and ARW were estimated from cone beam computed tomography images taken with radiological-surgical templates. Density and width values were similar in the 2 groups (P > .05). Implant coronal diameters were 3.75 mm in all cases, while consistent with the manufacturer's recommendations, final drill bit diameters used were 3.25 and 3.4 mm for parallel and tapered implants, respectively. Insertion torque was higher (P < .05) with parallel implants, but between-group differences in implant stability quotient were not significant (P > .05). In tapered implants, insertion torque was inversely correlated with ARW (P < .001). Notably, significant differences were observed between resonance frequency analysis values from Osstell and Penguin systems (P < .001). In conclusion, future studies should explore how PIS may be influenced by final drill bit size regardless of implant design and potential limits on the effectiveness of tapered implants to achieve good stability in thick low-density bone.

León (Spain) Health professionals' knowledge and clinical practice towards the relationship between cardiovascular diseases and periodontal disease.

Background: Cardiovascular pathologies have a high prevalence in the geriatric population, with acute myocardial infarction being one of the main causes of death in Spain. These pathologies have a systemic inflammatory component that is of vital importance. We also know in dentistry that the main gingival pathogens are capable of generating a systemic inflammatory response, being indirectly involved in the development of the atherosclerotic lesion, assuming, therefore, that periodontal disease is a cardiovascular risk factor. The objective of this study is to determine the knowledge of health professionals who treat cardiovascular diseases about periodontal disease and its relationship with heart disease. Material and Methods: A health survey was carried out on 100 Cardiologists, Internists and General Practitioners in the province of León. Points of interest in this survey: the professional's own oral health, knowledge of the relationship between periodontal and heart disease and, lastly, the training received in medicine on oral health. Results: 60% of professionals reviewed their oral health annually and 20% randomly. 48% of health professionals were unaware of periodontal diseases, 77% claimed to have not received university training in this regard, only 13% of those surveyed acknowledged having received more than 10 hours of training on oral health in their experience and finally, 90% thought that training in both Medicine and Dentistry should be collaborative. Conclusions: The degree of knowledge of health professionals regarding oral health is poor (77%), therefore the number of collaborative consultations with dental professionals is low (<63%). Training projects targeting a correct preventive medicine are shown to be necessary. Key words:Cardiovascular disease, oral-systemic health, periodontitis, knowledge, physicians.

Generating weighted and thresholded gene coexpression networks using signed distance correlation.

Even within well-studied organisms, many genes lack useful functional annotations. One way to generate such functional information is to infer biological relationships between genes or proteins, using a network of gene coexpression data that includes functional annotations. Signed distance correlation has proved useful for the construction of unweighted gene coexpression networks. However, transforming correlation values into unweighted networks may lead to a loss of important biological information related to the intensity of the correlation. Here we introduce a principled method to construct weighted gene coexpression networks using signed distance correlation. These networks contain weighted edges only between those pairs of genes whose correlation value is higher than a given threshold. We analyse data from different organisms and find that networks generated with our method based on signed distance correlation are more stable and capture more biological information compared to networks obtained from Pearson correlation. Moreover, we show that signed distance correlation networks capture more biological information than unweighted networks based on the same metric. While we use biological data sets to illustrate the method, the approach is general and can be used to construct networks in other domains. Code and data are available on https://github.com/javier-pardodiaz/sdcorGCN.

Erratum: Customer mobility and congestion in supermarkets [Phys. Rev. E 100, 062304 (2019)].

This corrects the article DOI: 10.1103/PhysRevE.100.062304.

Extracting Information from Gene Coexpression Networks of Rhizobium leguminosarum.

Nitrogen uptake in legumes is facilitated by bacteria such as Rhizobium leguminosarum. For this bacterium, gene expression data are available, but functional gene annotation is less well developed than for other model organisms. More annotations could lead to a better understanding of the pathways for growth, plant colonization, and nitrogen fixation in R. leguminosarum. In this study, we present a pipeline that combines novel scores from gene coexpression network analysis in a principled way to identify the genes that are associated with certain growth conditions or highly coexpressed with a predefined set of genes of interest. This association may lead to putative functional annotation or to a prioritized list of genes for further study.

Robust gene coexpression networks using signed distance correlation.

MOTIVATION: Even within well studied organisms, many genes lack useful functional annotations. One way to generate such functional information is to infer biological relationships between genes/proteins, using a network of gene coexpression data that includes functional annotations. However, the lack of trustworthy functional annotations can impede the validation of such networks. Hence, there is a need for a principled method to construct gene coexpression networks that capture biological information and are structurally stable even in the absence of functional information. RESULTS: We introduce the concept of signed distance correlation as a measure of dependency between two variables, and apply it to generate gene coexpression networks. Distance correlation offers a more intuitive approach to network construction than commonly used methods such as Pearson correlation and mutual information. We propose a framework to generate self-consistent networks using signed distance correlation purely from gene expression data, with no additional information. We analyse data from three different organisms to illustrate how networks generated with our method are more stable and capture more biological information compared to networks obtained from Pearson correlation or mutual information. SUPPLEMENTARY INFORMATION: Supplementary Information and code are available at Bioinformatics and https://github.com/javier-pardodiaz/sdcorGCN online.

Occupational mobility and automation: a data-driven network model.

The potential impact of automation on the labour market is a topic that has generated significant interest and concern amongst scholars, policymakers and the broader public. A number of studies have estimated occupation-specific risk profiles by examining how suitable associated skills and tasks are for automation. However, little work has sought to take a more holistic view on the process of labour reallocation and how employment prospects are impacted as displaced workers transition into new jobs. In this article, we develop a data-driven model to analyse how workers move through an empirically derived occupational mobility network in response to automation scenarios. At a macro level, our model reproduces the Beveridge curve, a key stylized fact in the labour market. At a micro level, our model provides occupation-specific estimates of changes in short and long-term unemployment corresponding to specific automation shocks. We find that the network structure plays an important role in determining unemployment levels, with occupations in particular areas of the network having few job transition opportunities. In an automation scenario where low wage occupations are more likely to be automated than high wage occupations, the network effects are also more likely to increase the long-term unemployment of low-wage occupations.

Alveolar Bone Density and Width Affect Primary Implant Stability.

Primary implant stability (PIS) depends on surgical technique, implant design, and recipient bone characteristics, among other factors. Bone density (BD) can be determined in Hounsfield units (HUs) using cone beam computerized tomography (CBCT). Reliable prediction of PIS could guide treatment decisions. We assessed whether PIS was associated with recipient bone characteristics, namely, BD and alveolar ridge width (ARW), measured preoperatively by CBCT. We studied a convenience sample of 160 implants placed in 48 patients in 2016 and 2017. All underwent CBCT with a radiologic/surgical guide yielding values for ARW and BD. PIS measures used were the implant stability quotient (ISQ) from resonance frequency analysis and insertion torque (IT). IT was most influenced by the HU value at 0.5 mm outside the implant placement area, followed by the value within this area, and ISQ by the HU value at 0.5 mm outside the placement area, followed by implant placement site and apical ARW. ISQ values were significantly related to ARW in coronal (P < .05), middle (P < .01), and apical (P < .01) thirds. ISQs were higher with larger-diameter implants (P < .01). ISQ and IT were strongly correlated (P < .001). PIS in terms of ISQ and IT is positively correlated with edentulous alveolar ridge BD measured by CBCT, implying that implant stability may be predicted preoperatively. Wide alveolar ridges favored lateral PIS but did not affect rotational PIS. The most significant predictor of lateral and rotational PIS in our patients was the HU value at 0.5 mm outside the implant placement area.

IMPACT OF CRUDE OIL ON FUNCTIONAL GROUPS OF CULTURABLE BACTERIA AND COLONIZATION OF SYMBIOTIC MICROORGANISMS IN THE Clitoria-Brachiaria RHIZOSPHERE GROWN IN MESOCOSMS / Impacto del petróleo crudo sobre grupos funcionales de bacterias cultivables y colonización de microorganismos simbióticos en la rizosfera de Clitoria-Brachiaria crecidas en mesocosmos

ABSTRACT This research evaluated the changes on populations of culturable N-fixing free bacteria (NFFB) and P-solubilizing bacteria (PSB), as well as on the root nodulation by native rhizobia, the root colonization and spore number of arbuscular mycorrhizal fungi (AMF), in the rhizosphere of Clitoria ternatea and Brachiaria brizantha grown in mesocosms contaminated with crude oil (0, 3000, 6000, 9000, and 12000 mg kg-1), for 240 days. After 24 h of soil contamination, the highest populations of NFFB and PSB (5.5 and 4.9 LogUFC, respectively) were found in control, and the lowest populations were obtained at 12000 mg kg-1 (5.1 and 4.2 LogUFC, respectively). In contrast, at 60 and 240 days, the control showed lower populations of NFFB and PSB (5.4 and 4.8 LogUFC, respectively) than contaminated treatments. The highest number of root nodules in C. ternatea was quantified in control at 60 and 240 days (25 and 27 nodules, respectively) in comparison to those observed at the treatment with 12000 mg kg-1 (7 and 1 nodule, respectively). At 60 days, AMF colonization in both plant species, and the number of spores significantly decreased as the crude oil concentration increased; however, at 240 days, the highest number of AMF spores was recorded at treatments with 6000 and 12000 mg kg-1. The dry weight of both plant species significantly decreased as crude oil concentrations increased. Although C. ternatea was more susceptible to the toxic effects of crude oil, this plant species showed greater content of total chlorophyll than B. brizantha.

RESUMEN Esta investigación evaluó los cambios en la población cultivable de bacterias de vida libre fijadoras de nitrógeno (BVLFN) y de bacterias solubilizadoras de fósforo (BSP), así como en la nodulación de raíces por rizobios nativos, y en la colonización y número de esporas de hongos micorrízicos arbusculares (HMA) en la rizósfera de Clitoria ternatea y Brachiaria brizantha cultivadas en mesocosmos contaminados con petróleo crudo (0, 3000, 6000, 9000 y 12000 mg kg-1), durante 240 días. A las 24 h de la contaminación del suelo, las poblaciones más altas de BVLFN y BSP (5,5 y 4,9 LogUFC, respectivamente) se encontraron en el control, mientras que las poblaciones más bajas se obtuvieron a 12000 mg kg-1 (5,1 y 4,2 LogUFC, respectivamente). En contraste, a los 60 y 240 días, el control mostró bajas poblaciones de BVLFN y BSP (5,4 y 4,8 LogUFC, respectivamente) que los tratamientos contaminados. El mayor número de nódulos en raíz de C. ternatea se cuantificó en el control a los 60 y 240 días (25 y 27 nódulos, respectivamente) en comparación con el tratamiento con 12000 mg kg-1 (7 y 1 nódulos, respectivamente). A los 60 días, la colonización de HMA en ambas especies vegetales y el número de esporas disminuyeron significativamente al aumentar la concentración de petróleo crudo; sin embargo, a los 240 días, se registró el mayor número de esporas de HMA en los tratamientos con 6000 y 12000 mg kg-1. El peso seco vegetal disminuyó significativamente al aumentar las concentraciones de petróleo crudo. Clitoria ternatea fue más susceptible a la toxicidad del petróleo, aunque esta especie vegetal mostró mayor contenido de clorofila total que B. brizantha.

Tensor clustering with algebraic constraints gives interpretable groups of crosstalk mechanisms in breast cancer.

We introduce a tensor-based clustering method to extract sparse, low-dimensional structure from high-dimensional, multi-indexed datasets. This framework is designed to enable detection of clusters of data in the presence of structural requirements which we encode as algebraic constraints in a linear program. Our clustering method is general and can be tailored to a variety of applications in science and industry. We illustrate our method on a collection of experiments measuring the response of genetically diverse breast cancer cell lines to an array of ligands. Each experiment consists of a cell line-ligand combination, and contains time-course measurements of the early signalling kinases MAPK and AKT at two different ligand dose levels. By imposing appropriate structural constraints and respecting the multi-indexed structure of the data, the analysis of clusters can be optimized for biological interpretation and therapeutic understanding. We then perform a systematic, large-scale exploration of mechanistic models of MAPK-AKT crosstalk for each cluster. This analysis allows us to quantify the heterogeneity of breast cancer cell subtypes, and leads to hypotheses about the signalling mechanisms that mediate the response of the cell lines to ligands.

Use of autologous tooth-derived graft material in the post-extraction dental socket. Pilot study

Background: The objectives of the present pilot study are to compare via CBCT the alveolar contraction suffered both vertically and horizontally between the control group and the group using autologous dental material (ADM), as well as to study the densitometric differences between both post-extraction sockets. Material and Methods: A split-mouth study was performed in n = 9 patients who required two extraction of single-rooted teeth deemed suitable for deferred rehabilitation with osseointegrated implants. Two groups were formed - a control group, in which the post-extraction socket was not filled, and an ADM group, in which the alveolar defect was filled with freshly processed autogenous dental material. Both dimensional and densitometric analyses of the alveoli were performed in both groups immediately after surgery (baseline), as well as 8 weeks and 16 weeks later. Results: The mean height of alveolar bone loss was: VL (Control 1.77 mm, loss of 16.87% of initial alveolar height; ADM 0.42 mm, loss of 4.2% of initial alveolar height), HL-BCB (Control 2.22 mm, ADM 0.16 mm, p= 0.067 at 16 weeks). The mean bone loss of the vestibular width (VL-BCB) was much higher in the control group (1.91 mm at 1 mm, 1.3 mm at 3 mm, and 0.89 mm at 5 mm) than in the ADM group (0.46 mm at 1 mm, 0.21 mm at 3 mm, 0.01 at 5 mm, p=0.098 at 16 weeks). At 16 weeks, densitometric analysis of the coronal alveolar area revealed a bone density of 564.35 ± 288.73 HU in the control group and 922.68 ± 250.82 HU in the ADM group (p=0.045 ). Conclusions: In light of these preliminary results, autologous dentine may be considered a promising material for use in socket preservation techniques

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Customer mobility and congestion in supermarkets.

The analysis and characterization of human mobility using population-level mobility models is important for numerous applications, ranging from the estimation of commuter flows in cities to modeling trade flows between countries. However, almost all of these applications have focused on large spatial scales, which typically range between intracity scales and intercountry scales. In this paper, we investigate population-level human mobility models on a much smaller spatial scale by using them to estimate customer mobility flow between supermarket zones. We use anonymized, ordered customer-basket data to infer empirical mobility flow in supermarkets, and we apply variants of the gravity and intervening-opportunities models to fit this mobility flow and estimate the flow on unseen data. We find that a doubly-constrained gravity model and an extended radiation model (which is a type of intervening-opportunities model) can successfully estimate 65%-70% of the flow inside supermarkets. Using a gravity model as a case study, we then investigate how to reduce congestion in supermarkets using mobility models. We model each supermarket zone as a queue, and we use a gravity model to identify store layouts with low congestion, which we measure either by the maximum number of visits to a zone or by the total mean queue size. We then use a simulated-annealing algorithm to find store layouts with lower congestion than a supermarket's original layout. In these optimized store layouts, we find that popular zones are often in the perimeter of a store. Our research gives insight both into how customers move in supermarkets and into how retailers can arrange stores to reduce congestion. It also provides a case study of human mobility on small spatial scales.

A new species of Microtetrameres (Nematoda, Tetrameridae) parasitizing Buteogallus urubitinga (Aves, Accipitridae) from northeastern Argentina.

A new tetramerid nematode, Microtetrameres urubitinga n. sp., is described from specimens recovered from the proventriculus of the great black-hawk, Buteogallus urubitinga (Aves: Accipitridae), from Formosa Province, Argentina. The males of the new species are characterized by having spicules unequal (length ratio of spicules 1:3.8-5.9) and dissimilar in shape (right spicule with a simple tip, left spicule with a symmetrical bifurcated tip), caudal papillae arranged asymmetrically (two pairs precloacal and two pairs postcloacal) and cloacal lips highly protruded forming a tube. The gravid females are permanently coiled clockwise or counterclockwise in a spiral and having a tail tapering gradually to a sharp point, with a cuticular fold. This is the first nominal species of Microtetrameres (Travassos, 1915) described parasitizing birds from Argentina. The relationship between the diet of B. urubitinga and the low prevalence of M. urubitinga n. sp. is discussed.

Flux-dependent graphs for metabolic networks.

Cells adapt their metabolic fluxes in response to changes in the environment. We present a framework for the systematic construction of flux-based graphs derived from organism-wide metabolic networks. Our graphs encode the directionality of metabolic flows via edges that represent the flow of metabolites from source to target reactions. The methodology can be applied in the absence of a specific biological context by modelling fluxes probabilistically, or can be tailored to different environmental conditions by incorporating flux distributions computed through constraint-based approaches such as Flux Balance Analysis. We illustrate our approach on the central carbon metabolism of Escherichia coli and on a metabolic model of human hepatocytes. The flux-dependent graphs under various environmental conditions and genetic perturbations exhibit systemic changes in their topological and community structure, which capture the re-routing of metabolic flows and the varying importance of specific reactions and pathways. By integrating constraint-based models and tools from network science, our framework allows the study of context-specific metabolic responses at a system level beyond standard pathway descriptions.

Intoxicación grave con nafazolina: puesta al día a partir de un error terapéutico / Severe poisoning with naphazoline: update from a therapeutic error

La nafazolina es un fármaco utilizado como descongestivo, generalmente, en pacientes adultos. Su indicación en pediatría no es frecuente; su uso está aprobado a partir de los 12 años por los efectos tóxicos que posee. La intoxicación en niños genera un cuadro clínico potencialmente grave. Se caracteriza por la aparición inmediata de hipotonía, deterioro del sensorio, hipotermia y bradicardia con grado variable de compromiso clínico. Si bien es una intoxicación infrecuente, la anamnesis y el manejo inicial del paciente son la clave en su evolución. Se presenta a un niño de 4 años que, por un error terapéutico, recibió este fármaco y se destaca la instauración rápida y potencialmente grave del cuadro clínico.

Naphazoline is a drug commonly used as a decongestant in adult patients. Its indication in Pediatrics is not frequent, being approved its use from the age of 12 for the toxic effects it possesses. Intoxication in children generates a potentially serious clinical picture. It is characterized by the immediate appearance of hypotonia, deterioration of the sensory, hypothermia and bradycardia of variable degree of clinical compromise. Although it is an infrequent intoxication, the anamnesis and the initial management of the patient are the key in the evolution. We present a 4-year-old boy who, as a therapeutic error, receives this drug, emphasizing the rapid and potentially severe establishment of the clinical picture.

[Severe poisoning with naphazoline: update from a therapeutic error]. / Intoxicación grave con nafazolina: puesta al día a partir de un error terapéutico.

Naphazoline is a drug commonly used as a decongestant in adult patients. Its indication in Pediatrics is not frequent, being approved its use from the age of 12 for the toxic effects it possesses. Intoxication in children generates a potentially serious clinical picture. It is characterized by the immediate appearance of hypotonia, deterioration of the sensory, hypothermia and bradycardia of variable degree of clinical compromise. Although it is an infrequent intoxication, the anamnesis and the initial management of the patient are the key in the evolution. We present a 4-year-old boy who, as a therapeutic error, receives this drug, emphasizing the rapid and potentially severe establishment of the clinical picture.

La nafazolina es un fármaco utilizado como descongestivo, generalmente, en pacientes adultos. Su indicación en pediatría no es frecuente; su uso está aprobado a partir de los 12 años por los efectos tóxicos que posee. La intoxicación en niños genera un cuadro clínico potencialmente grave. Se caracteriza por la aparición inmediata de hipotonía, deterioro del sensorio, hipotermia y bradicardia con grado variable de compromiso clínico. Si bien es una intoxicación infrecuente, la anamnesis y el manejo inicial del paciente son la clave en su evolución. Se presenta a un niño de 4 años que, por un error terapéutico, recibió este fármaco y se destaca la instauración rápida y potencialmente grave del cuadro clínico.

Integrating sentiment and social structure to determine preference alignments: the Irish Marriage Referendum.

We examine the relationship between social structure and sentiment through the analysis of a large collection of tweets about the Irish Marriage Referendum of 2015. We obtain the sentiment of every tweet with the hashtags #marref and #marriageref that was posted in the days leading to the referendum, and construct networks to aggregate sentiment and use it to study the interactions among users. Our analysis shows that the sentiment of outgoing mention tweets is correlated with the sentiment of incoming mentions, and there are significantly more connections between users with similar sentiment scores than among users with opposite scores in the mention and follower networks. We combine the community structure of the follower and mention networks with the activity level of the users and sentiment scores to find groups that support voting 'yes' or 'no' in the referendum. There were numerous conversations between users on opposing sides of the debate in the absence of follower connections, which suggests that there were efforts by some users to establish dialogue and debate across ideological divisions. Our analysis shows that social structure can be integrated successfully with sentiment to analyse and understand the disposition of social media users around controversial or polarizing issues. These results have potential applications in the integration of data and metadata to study opinion dynamics, public opinion modelling and polling.

Intoxicación masiva con monóxido de carbono: puesta al día a partir de un caso / Massive poisoning with carbon monoxide: an update from a case

El monóxido de carbono es conocido como " el asesino silencioso" por tratarse de un gas incoloro e inodoro. De acuerdo con estas características, su toxicidad pasa desapercibida, lo cual dificulta arribar al diagnóstico. En la mayoría de los casos, las épocas frías y la intoxicación grupal hacen sospechar su presencia, debido a que se utilizan formas inapropiadas de calefacción tanto en el ámbito domiciliario como público. Nuestro objetivo es dar a conocer una intoxicación masiva con monóxido de carbono en un salón de fiestas infantiles en el que se utilizó una fuente de combustión instalada, no con el fin de calefaccionar, sino como abastecimiento de luz (grupo electrógeno). Se recalca que también puede ocurrir en cualquier época del año.

Carbon monoxide is known as the " silent murderer" because it is a colorless and odorless gas. According to these characteristics, toxicity goes unnoticed which makes the diagnosis difficult. In most cases, the cold periods and group poisoning make suspect its presence because inappropriate heat both in home or public environments. Our goal is to inform about a mass carbon monoxide poisoning in a children's parties room using a combustion source installed, not for the purpose of heating, but as a supply of light (generator), emphasizing that it can occur in any time of the year.

[Massive poisoning with carbon monoxide: an update from a case]. / Intoxicación masiva con monóxido de carbono: puesta al día a partir de un caso.

Carbon monoxide is known as the "silent murderer" because it is a colorless and odorless gas. According to these characteristics, toxicity goes unnoticed which makes the diagnosis difficult. In most cases, the cold periods and group poisoning make suspect its presence because inappropriate heat both in home or public environments. Our goal is to inform about a mass carbon monoxide poisoning in a children's parties room using a combustion source installed, not for the purpose of heating, but as a supply of light (generator), emphasizing that it can occur in any time of the year.

El monóxido de carbono es conocido como "el asesino silencioso" por tratarse de un gas incoloro e inodoro. De acuerdo con estas características, su toxicidad pasa desapercibida, lo cual dificulta arribar al diagnóstico. En la mayoría de los casos, las épocas frías y la intoxicación grupal hacen sospechar su presencia, debido a que se utilizan formas inapropiadas de calefacción tanto en el ámbito domiciliario como público. Nuestro objetivo es dar a conocer una intoxicación masiva con monóxido de carbono en un salón de fiestas infantiles en el que se utilizó una fuente de combustión instalada, no con el fin de calefaccionar, sino como abastecimiento de luz (grupo electrógeno). Se recalca que también puede ocurrir en cualquier época del año.