AVIP Project (Prosthetic Virtual Friend): Study of clinical-functional outcomes and satisfaction with a mobile application in the perioperative management and follow-up of hip arthroplasty. / Proyecto AVIP (Amigo VIrtual Protésico): estudio de resultados clínico-funcionales y de satisfacción con una aplicación móvil en el manejo perioperatorio y seguimiento de implantes protésicos de cadera.

OBJECTIVE: To analyze the clinical, quality of life, and healthcare quality outcomes obtained in a series of patients undergoing total hip arthroplasty (THA), who were empowered and monitored using the AVIP application. These results will be compared with a control group followed through a standard protocol. MATERIAL AND METHOD: Randomized clinical trial with parallel groups involving patients with an indication for THA. Clinical variables were measured and compared using the WOMAC and mHHS, pain assessed by the VAS, quality of life with the SF-12 test. Walking capabilities were analyzed using the Functional Gait Assessment Scale, along with satisfaction levels assessed through the SUCE questionnaire, and perceived anxiety levels related to the process. RESULTS: A total of 68 patients were evaluated, with 31 patients in the AVIP group and 33 in the Control group completing the follow-up. Both groups demonstrated improvement in clinical outcomes based on the WOMAC and mHHS hip tests, a reduction in perceived pain, and an enhancement in quality of life according to the SF-12 test. Patients in the AVIP study group exhibited non-inferiority in clinical outcomes and satisfaction compared to the control group, as well as lower anxiety levels and improved walking capabilities after the first month of follow-up. Notably, 82.25% of the follow-up visits for this group were conducted remotely. CONCLUSION: The implementation of a mHealth application like AVIP can be safely offered to selected patients undergoing hip arthroplasty, enabling effective monitoring and providing continuous information and training.

Diseño y comparativa de biomateriales para el tratamiento de defectos óseos. Estudio de su comportamiento in vivo en modelo animal de conejo / Desing and comparison of bone substitutes. Study of in vivo behavior in a rabbit model

Objetivo: Comparar in vivo la capacidad de formación ósea de dos tipos de biomateriales diseñados como sustitutivos óseos respecto a autoinjerto de cresta iliaca, uno basado en carbonatohidroxiapatita y otro en vidrio mesoporoso bioactivo. Material y método: Estudio experimental compuesto por 14 conejos de Nueva Zelanda hembras adultas donde se realizó un defecto crítico en hueso radio. La muestra fue dividida en cuatro grupos: defecto sin material, con autoinjerto de cresta iliaca, con soporte de carbonatohidroxiapatita y con soporte de vidrio mesoporoso bioactivo. Se realizaron estudios seriados de radiología simple a las 2, 4, 6 y 12 semanas y estudio de micro-TC a eutanasia a las 6 y 12 semanas. Resultados: En el estudio de radiología simple, el grupo de autoinjerto mostró las mayores puntuaciones de formación ósea (7,5 puntos). Ambos grupos de biomateriales presentaron formación ósea similar (5,3 y 6 puntos, respectivamente) y mayor al defecto sin material (4 puntos), pero siempre menor que el grupo de autoinjerto. Los resultados del estudio de micro-TC mostraron el mayor volumen de hueso en el área de estudio en el grupo de autoinjerto. Los grupos con sustitutivos óseos presentaron mayor volumen de hueso que el grupo sin material, pero siempre menor que en el grupo de autoinjerto. Conclusiones: Ambos soportes parecen favorecer la formación ósea pero no son capaces de reproducir las características del autoinjerto. Por sus diferentes características macroscópicas cada uno podría ser adecuado para un tipo diferente de defecto.(AU)

Aim: Compare bone formation capacity in vivo of two types of biomaterials designed as bone substitutes with respect to iliac crest autograft, one based on carbonate hydroxyapatites and the other one on bioactive mesoporous glass. Materials and methods: Experimental study consisting on 14 adult female New Zeland rabbits where a critical defect was made in the rabbit radius bone. The sample was divided into four groups: defect without material, with iliac crest autograft, with carbonatehydroxyapatite support, and with bioactive mesoporous glass support. Serial X-ray studies were carried out at 2, 4, 6 and 12 weeks and a microCT study at euthanasia at 6 and 12 weeks. Results: In the X-ray study, autograft group showed the highest bone formation scores. Both groups of biomaterials presented bone formation similar and greater than the defect without material, but always less than in the autograft group. The results of the microCT study showed the largest bone volume in the study area in the autograft group. The groups with bone substitutes presented greater bone volume than the group without material but always less than in the autograft group. Conclusion: Both supports seem to promote bone formation but are not capable of reproducing the characteristics of autograft. Due to their different macroscopic characteristics, each one could be suitable for a different type of defect.(AU)

[Translated article] Design and comparison of bone substitutes. Study of in vivo behaviour in a rabbit model / Diseño y comparativa de biomateriales para el tratamiento de defectos óseos. Estudio de su comportamiento in vivo en modelo animal de conejo

Objetivo: Comparar in vivo la capacidad de formación ósea de dos tipos de biomateriales diseñados como sustitutivos óseos respecto a autoinjerto de cresta iliaca, uno basado en carbonatohidroxiapatita y otro en vidrio mesoporoso bioactivo. Material y método: Estudio experimental compuesto por 14 conejos de Nueva Zelanda hembras adultas donde se realizó un defecto crítico en hueso radio. La muestra fue dividida en cuatro grupos: defecto sin material, con autoinjerto de cresta iliaca, con soporte de carbonatohidroxiapatita y con soporte de vidrio mesoporoso bioactivo. Se realizaron estudios seriados de radiología simple a las 2, 4, 6 y 12 semanas y estudio de micro-TC a eutanasia a las 6 y 12 semanas. Resultados: En el estudio de radiología simple, el grupo de autoinjerto mostró las mayores puntuaciones de formación ósea (7,5 puntos). Ambos grupos de biomateriales presentaron formación ósea similar (5,3 y 6 puntos, respectivamente) y mayor al defecto sin material (4 puntos), pero siempre menor que el grupo de autoinjerto. Los resultados del estudio de micro-TC mostraron el mayor volumen de hueso en el área de estudio en el grupo de autoinjerto. Los grupos con sustitutivos óseos presentaron mayor volumen de hueso que el grupo sin material, pero siempre menor que en el grupo de autoinjerto. Conclusiones: Ambos soportes parecen favorecer la formación ósea pero no son capaces de reproducir las características del autoinjerto. Por sus diferentes características macroscópicas cada uno podría ser adecuado para un tipo diferente de defecto.(AU)

Aim: Compare bone formation capacity in vivo of two types of biomaterials designed as bone substitutes with respect to iliac crest autograft, one based on carbonate hydroxyapatites and the other one on bioactive mesoporous glass. Materials and methods: Experimental study consisting on 14 adult female New Zeland rabbits where a critical defect was made in the rabbit radius bone. The sample was divided into four groups: defect without material, with iliac crest autograft, with carbonatehydroxyapatite support, and with bioactive mesoporous glass support. Serial X-ray studies were carried out at 2, 4, 6 and 12 weeks and a microCT study at euthanasia at 6 and 12 weeks. Results: In the X-ray study, autograft group showed the highest bone formation scores. Both groups of biomaterials presented bone formation similar and greater than the defect without material, but always less than in the autograft group. The results of the microCT study showed the largest bone volume in the study area in the autograft group. The groups with bone substitutes presented greater bone volume than the group without material but always less than in the autograft group. Conclusion: Both supports seem to promote bone formation but are not capable of reproducing the characteristics of autograft. Due to their different macroscopic characteristics, each one could be suitable for a different type of defect.(AU)

Implantes de titanio trabecular en cirugía de revisión acetabular compleja / Trabecular titanium implants in complex acetabular revision surgery

Introducción: La cirugía de revisión acetabular supone un reto quirúrgico sobre todo cuando aparecen los defectos óseos complejos, pues dificultan la fijación primaria y osteointegración de los implantes, lo que condiciona la aparición de complicaciones. Los cotilos de titanio trabecular intentan solventar estos problemas. Objetivos: Valorar los resultados clínico-radiológicos, la supervivencia de los implantes y aparición de complicaciones a medio plazo en cirugía de revisión acetabular en una serie de 37 recambios acetabulares con defectos óseos tipo IIIA y IIIB de Paprosky en los que se utilizó un implante de revisión tipo Cup-Cage de titanio trabecular. Material y método: Realizamos un estudio observacional, descriptivo y retrospectivo de 37 casos con defectos acetabulares complejos (20 tipo IIIA y 17 tipo IIIB, cinco de ellos con discontinuidad pélvica) en los que se realizó recambio del componente acetabular por implantes de titanio trabecular entre los años 2011 y 2019. Analizamos resultados clínicos (dolor y funcionalidad) y parámetros radiológicos (restauración del centro de rotación de la cadera y la movilización de los implantes), así como la aparición de complicaciones. Resultados: El seguimiento medio fue de 61 meses. Obtuvimos una mejoría en la mediana de 8 puntos en la escala de funcionalidad de Merlé D’Aubigné-Postel y de 6 puntos en la escala EVA de dolor percibido por el paciente. Registramos dos casos de aflojamiento acetabular, un caso de inestabilidad y tres infecciones de herida quirúrgica sin afectar al implante. Conclusiones: La utilización de implantes tipo Cup-Cage de titanio trabecular podría constituir una opción válida en cirugía de revisión acetabular con defectos acetabulares complejos, presentando buenos resultados clínico-radiológicos y en cuanto a complicaciones y supervivencia de los implantes, debido a su buena fijación primaria y osteointegración.(AU)

Introduction: Acetabular revision surgery is a surgical challenge, especially when complex bone defects appear. This makes primary fixation and osseointegration of the implants difficult, which conditions the appearance of complications. Trabecular titanium implants attempt to solve these problems. Objectives: To evaluate our clinical-radiological results, the survival of the implants and the appearance of mid-term complications in acetabular revision surgery in a series of 37 acetabular replacements with Paprosky type IIIA and IIIB bone defects in which a trabecular titanium Cup-Cage revision implant was used. Material and method: We conducted an observational, descriptive and retrospective study of 37 cases with complex acetabular defects (20 type IIIA and 17 type IIIB, five of them with pelvic discontinuity) in which the acetabular component was replaced by trabecular titanium cups between 2011 and 2019. We analyzed clinical results (pain and functionality) and radiological parameters (restoration of the hip rotation centre and the mobilization of the implants), as well as the appearance of complications. Results: The mean follow-up was 61 months. We obtained a median improvement of 8 points on the Merlé D’Aubigné-Postel functionality scale and 6 points on the VAS scale of pain perceived by the patient. We recorded two cases of acetabular loosening, one case of dislocation and three surgical wound infections without affecting the implant. Conclusions: The use of trabecular titanium Cup-Cage implants could be a valid option in acetabular revision surgery with complex acetabular defects, presenting good clinical and radiological results and in terms of complications and survival of the implants, mainly due to their good primary fixation and subsequent osseointegration.(AU)

[Translated article] Trabecular titanium implants in complex acetabular revision surgery / Implantes de titanio trabecular en cirugía de revisión acetabular compleja

Introducción: La cirugía de revisión acetabular supone un reto quirúrgico sobre todo cuando aparecen los defectos óseos complejos, pues dificultan la fijación primaria y osteointegración de los implantes, lo que condiciona la aparición de complicaciones. Los cotilos de titanio trabecular intentan solventar estos problemas. Objetivos: Valorar los resultados clínico-radiológicos, la supervivencia de los implantes y aparición de complicaciones a medio plazo en cirugía de revisión acetabular en una serie de 37 recambios acetabulares con defectos óseos tipo IIIA y IIIB de Paprosky en los que se utilizó un implante de revisión tipo Cup-Cage de titanio trabecular. Material y método: Realizamos un estudio observacional, descriptivo y retrospectivo de 37 casos con defectos acetabulares complejos (20 tipo IIIA y 17 tipo IIIB, cinco de ellos con discontinuidad pélvica) en los que se realizó recambio del componente acetabular por implantes de titanio trabecular entre los años 2011 y 2019. Analizamos resultados clínicos (dolor y funcionalidad) y parámetros radiológicos (restauración del centro de rotación de la cadera y la movilización de los implantes), así como la aparición de complicaciones. Resultados: El seguimiento medio fue de 61 meses. Obtuvimos una mejoría en la mediana de 8 puntos en la escala de funcionalidad de Merlé D’Aubigné-Postel y de 6 puntos en la escala EVA de dolor percibido por el paciente. Registramos dos casos de aflojamiento acetabular, un caso de inestabilidad y tres infecciones de herida quirúrgica sin afectar al implante. Conclusiones: La utilización de implantes tipo Cup-Cage de titanio trabecular podría constituir una opción válida en cirugía de revisión acetabular con defectos acetabulares complejos, presentando buenos resultados clínico-radiológicos y en cuanto a complicaciones y supervivencia de los implantes, debido a su buena fijación primaria y osteointegración.(AU)

Introduction: Acetabular revision surgery is a surgical challenge, especially when complex bone defects appear. This makes primary fixation and osseointegration of the implants difficult, which conditions the appearance of complications. Trabecular titanium implants attempt to solve these problems. Objectives: To evaluate our clinical-radiological results, the survival of the implants and the appearance of mid-term complications in acetabular revision surgery in a series of 37 acetabular replacements with Paprosky type IIIA and IIIB bone defects in which a trabecular titanium Cup-Cage revision implant was used. Material and method: We conducted an observational, descriptive and retrospective study of 37 cases with complex acetabular defects (20 type IIIA and 17 type IIIB, five of them with pelvic discontinuity) in which the acetabular component was replaced by trabecular titanium cups between 2011 and 2019. We analyzed clinical results (pain and functionality) and radiological parameters (restoration of the hip rotation centre and the mobilization of the implants), as well as the appearance of complications. Results: The mean follow-up was 61 months. We obtained a median improvement of 8 points on the Merlé D’Aubigné-Postel functionality scale and 6 points on the VAS scale of pain perceived by the patient. We recorded two cases of acetabular loosening, one case of dislocation and three surgical wound infections without affecting the implant. Conclusions: The use of trabecular titanium Cup-Cage implants could be a valid option in acetabular revision surgery with complex acetabular defects, presenting good clinical and radiological results and in terms of complications and survival of the implants, mainly due to their good primary fixation and subsequent osseointegration.(AU)

Association of positive psychological variables with disease activity, functional disability and erythrocyte sedimentation rate in patients with rheumatoid arthritis: a preliminary study.

Rheumatoid arthritis (RA) is a chronic autoimmune disease which has shown positive correlations between negative psychological variables and disease activity in transversal studies and in the follow-up. However, the association of positive psychological variables with disease parameters including disease activity (DAS-28), functional disability (HAQ) and erythrocyte sedimentation rate (ESR) has not been investigated. Patients with RA attending the external consultation of a third level hospital were invited to participate and fill in a questionnaire with personal, disease and psychological variables; body mass index was also obtained as well as ESR. A total of 49 patients were included. The three dependent variables correlated among them, with the highest correlation for DAS-28 and HAQ (r=0.645, p<0.01), followed by somatization and HAQ (r=0.614, p<0.01) or DAS-28 (r=0.537, P<0.01). In addition, HAQ showed negative correlations with environmental mastery (r=- 0.366, p<0.01), personal growth (r=-0.292, p<0.05) and monthly extra money (r=-0.328, p<0.05), and borderline negative correlations with emotion perception (r=-0.279, p=0.053) and self-acceptance (r=-0.250, p=0.08). ESR showed a significant negative correlation with emotion perception (r=-0.475, p<0.01). In conclusion, we observed important correlations of positive psychological variables with disease activity, functional disability and ESR that could be addressed in order to prevent or treat these disease features.

[Translated article] Design and comparison of bone substitutes. Study of in vivo behaviour in a rabbit model.

AIM: To compare the in vivo bone formation capacity of of biomaterials designed as bone substitutes with respect to iliac crest autograft, one based on carbonate hydroxiapatite and the other one on bioactive mesoporous glass. MATERIALS AND METHODS: Experimental study consisting on 14 adult female New Zeland rabbits where a critical defect was made in the rabbit radius bone. The sample was divided into four groups: defect without material, with iliac crest autograft, with carbonatehydroxyapatite scaffold, and with bioactive mesoporous glass scaffold. Serial X-ray studies were carried out at 2, 4, 6 and 12 weeks and a microCT study at euthanasia at 6 and 12 weeks. RESULTS: In the X-ray study, autograft group showed the highest bone formation scores. Both groups of biomaterials presented bone formation similar and greater than the defect without material, but always less than in the autograft group. The results of the microCT study showed the largest bone volume in the study area in the autograft group. The groups with bone substitutes presented greater bone volume than the group without material but always less than the autograft group. CONCLUSION: Both scaffolds seem to promote bone formation but are not capable of reproducing the characteristics of autograft. Due to their different macroscopic characteristics, each one could be suitable for a different type of defect.

Desing and comparison of bone substitutes. Study of in vivo behavior in a rabbit model. / Diseño y comparativa de biomateriales para el tratamiento de defectos óseos. Estudio de su comportamiento in vivo en modelo animal de conejo.

AIM: Compare bone formation capacity in vivo of two types of biomaterials designed as bone substitutes with respect to iliac crest autograft, one based on carbonate hydroxyapatites and the other one on bioactive mesoporous glass. MATERIALS AND METHODS: Experimental study consisting on 14 adult female New Zeland rabbits where a critical defect was made in the rabbit radius bone. The sample was divided into four groups: defect without material, with iliac crest autograft, with carbonatehydroxyapatite support, and with bioactive mesoporous glass support. Serial X-ray studies were carried out at 2, 4, 6 and 12 weeks and a microCT study at euthanasia at 6 and 12 weeks. RESULTS: In the X-ray study, autograft group showed the highest bone formation scores. Both groups of biomaterials presented bone formation similar and greater than the defect without material, but always less than in the autograft group. The results of the microCT study showed the largest bone volume in the study area in the autograft group. The groups with bone substitutes presented greater bone volume than the group without material but always less than in the autograft group. CONCLUSION: Both supports seem to promote bone formation but are not capable of reproducing the characteristics of autograft. Due to their different macroscopic characteristics, each one could be suitable for a different type of defect.

Methoprene treatment and its effect on male reproductive organ size and female remating in a fruit fly.

Methoprene, a juvenile hormone analog, is used to accelerate sexual maturation in males of species of economic importance in support to the sterile insect technique (SIT). In the SIT, mass-reared sterile males are released into the field and need to survive until they reach sexual maturation, find a wild female, mate with her and then induce female sexual refractoriness, so she will not remate with a wild counterpart. The use of methoprene shortens the time between release and copulation. However, in South American fruit flies, Anastrepha fraterculus, the ability of methoprene-treated males to inhibit female remating has been shown to be lower than wild males, when methoprene was applied by pupal immersion or topical application. Here we evaluated the possibility of incorporating methoprene into the male diet at different doses and the ability of those males to inhibit female remating, as well as the effect of methoprene on male reproductive organ size, due to the possible correlation between male accessory gland size and their content, and the role of male accessory gland proteins in female inhibition. We found that A. fraterculus males fed with methoprene in the adult protein diet at doses as high as 1% were less likely to inhibit female remating, however, at all other lower doses males had the same ability as untreated males to inhibit female remating. Males fed with methoprene had bigger male accessory glands and testes compared to methoprene-deprived males. We demonstrate that the incorporation of methoprene in adult male diets is possible in this species and potentially useful as a post-teneral, pre-release supplement at doses as low as 0.01%. Even at higher doses, the percentage of females remating after 48 h from the first copulation is sufficiently low in this species so as not compromise the efficiency of the SIT.

[Translated article] Trabecular titanium implants in complex acetabular revision surgery.

INTRODUCTION: Acetabular revision surgery is a surgical challenge, especially when complex bone defects appear. This makes primary fixation and osseointegration of the implants difficult, which conditions the appearance of complications. Trabecular titanium implants attempt to solve these problems. OBJECTIVES: To evaluate our clinical-radiological results, the survival of the implants and the appearance of mid-term complications in acetabular revision surgery in a series of 37 acetabular replacements with Paprosky type IIIA and IIIB bone defects in which a trabecular titanium Cup-Cage revision implant was used. MATERIAL AND METHOD: We conducted an observational, descriptive and retrospective study of 37 cases with complex acetabular defects (20 type IIIA and 17 type IIIB, five of them with pelvic discontinuity) in which the acetabular component was replaced by trabecular titanium cups between 2011 and 2019. We analysed clinical results (pain and functionality) and radiological parameters (restoration of the hip rotation centre and the mobilisation of the implants), as well as the appearance of complications. RESULTS: The mean follow-up was 61 months. We obtained a median improvement of 8 points on the Merlé D'Aubigné-Postel functionality scale and 6 points on the VAS scale of pain perceived by the patient. We recorded two cases of acetabular loosening, one case of dislocation and three surgical wound infections without affecting the implant. CONCLUSIONS: The use of trabecular titanium Cup-Cage implants could be a valid option in acetabular revision surgery with complex acetabular defects, presenting good clinical and radiological results and in terms of complications and survival of the implants, mainly due to their good primary fixation and subsequent osseointegration.

Trabecular titanium implants in complex acetabular revision surgery. / Implantes de titanio trabecular en cirugía de revisión acetabular compleja.

INTRODUCTION: Acetabular revision surgery is a surgical challenge, especially when complex bone defects appear. This makes primary fixation and osseointegration of the implants difficult, which conditions the appearance of complications. Trabecular titanium implants attempt to solve these problems. OBJECTIVES: To evaluate our clinical-radiological results, the survival of the implants and the appearance of mid-term complications in acetabular revision surgery in a series of 37 acetabular replacements with Paprosky type IIIA and IIIB bone defects in which a trabecular titanium Cup-Cage revision implant was used. MATERIAL AND METHOD: We conducted an observational, descriptive and retrospective study of 37 cases with complex acetabular defects (20 type IIIA and 17 type IIIB, five of them with pelvic discontinuity) in which the acetabular component was replaced by trabecular titanium cups between 2011 and 2019. We analyzed clinical results (pain and functionality) and radiological parameters (restoration of the hip rotation centre and the mobilization of the implants), as well as the appearance of complications. RESULTS: The mean follow-up was 61 months. We obtained a median improvement of 8 points on the Merlé D'Aubigné-Postel functionality scale and 6 points on the VAS scale of pain perceived by the patient. We recorded two cases of acetabular loosening, one case of dislocation and three surgical wound infections without affecting the implant. CONCLUSIONS: The use of trabecular titanium Cup-Cage implants could be a valid option in acetabular revision surgery with complex acetabular defects, presenting good clinical and radiological results and in terms of complications and survival of the implants, mainly due to their good primary fixation and subsequent osseointegration.

Fracturas de acetábulo tratadas mediante osteosíntesis. Resultados a largo plazo / Surgical treatment of acetabular fractures. Long term outcomes

Resumen: Introducción: las fracturas de acetábulo constituyen entre el 0.3 y 0.6% total de fracturas observadas, siendo estás lesiones relativamente infrecuentes. Objetivo: evaluar los resultados clínico-radiológicos del tratamiento quirúrgico mediante osteosíntesis de fracturas acetabulares con un seguimiento mínimo de 11.5 años. El objetivo secundario fue determinar la tasa de fracaso de la cadera de estos pacientes e identificar los factores de riesgo implicados. Materia y métodos: analizamos retrospectivamente una muestra de 23 pacientes intervenidos de fractura acetabular mediante reducción abierta y fijación interna, con un seguimiento medio de 14 años (11.5-17.5). Clasificamos las fracturas según Judet y Letournel en simples y complejas. Analizamos la evolución clínica y radiológica de estos pacientes mediante la escala de Harris. Resultados: obtuvimos una puntuación media de 81.90/100, objetivamos mejores resultados en fracturas de trazo simple respecto a fracturas complejas (p = 0.027). Evidenciamos mejores resultados clínicos en los pacientes con una reducción anatómica de la fractura (86.9/100), respecto a los que no fue posible (74.38/100) (p = 0.033). Fue necesaria la reintervención con artroplastía por mala evolución clínica en tres pacientes (13%). Como predictores de mal pronóstico para el desarrollo de coxartrosis identificamos las fracturas complejas y la reducción no anatómica de la fractura (p < 0.05). Encontramos relación entre índice de masa corporal (IMC) > 30 con peores resultados funcionales (p = 0.151). Conclusiones: el tratamiento quirúrgico de pacientes tratados con fracturas acetabulares presenta buenos resultados clínicos y radiológicos a largo plazo. Como factores de riesgo para la progresión de coxartrosis con suficiente impronta clínica como para ser necesaria una artroplastía identificamos, las fracturas complejas, la reducción no anatómica y un IMC > 30.

Abstract: Introduction: acetabular fractures constitute between 0.3 and 0.6% of all observed fractures, being these injuries relatively infrequent. Objective: to evaluate clinical and radiological outcomes of surgical treatment of patients with acetabular fracture treated in our hospital with a minimal follow-up of 11.5 years. The secondary objective is to determine the rate of failure in the hip joint of these patients and establish risk factors that are involved. Material and methods: 23 patients with acetabular fractures that were treated by open reduction and internal fixation (ORIF) were retrospectively analysed. They were follow-up during an average of 14 years (range 11.5-17.5). Fractures were classified by Judet y Letournel as simple or complex. Clinical and radiological outcomes were analysed by Harris scale. Results: We obtained an average of 81.90/100 on the Harris scale, aiming at better outcomes on simple fractures compare to those that were complex (p = 0.027). Higher scores were also achieved on those patients with an anatomical reduction (p = 0.033). Three patients required revision and placement of a total arthoplasty (13%). However, patients with body mass index (BMI) > 30 tend to achieve poor clinical results (p = 0.151). Conclusions: ORIF may be suggested for acetabular fractures since good clinical and radiological outcomes were recorded on a long-term follow-up. Complex fractures, non-anatomical reduction and BMI > 30 were identified as risk factors to coxarthrosis progression.

Have acute appendicitis complications increased in children as a result of SARS-CoV-2? / ¿Han aumentado las complicaciones de las apendicitis agudas en niños por el impacto del SARS-CoV-2?

INTRODUCTION: The impact of the SARS-CoV-2 pandemic on healthcare has already been described, since it has caused an increase in diagnostic delay and morbidity. Our objective was to assess its influence on the development of complications in children with acute appendicitis. MATERIALS AND METHODS: A retrospective cohort study was carried out. It included acute appendicitis patients under 15 years of age treated from January 1, 2019 to December 31, 2020. They were classified according to diagnosis date as before the pandemic (B) (January 2019-February 2020) and during the pandemic (D) (March 2020-December 2020). According to operative findings, they were classified as complicated appendicitis (perforated/abscess/plastron/peritonitis) and non-complicated appendicitis (catarrhal/phlegmonous/gangrenous). Demographic data, progression time, and postoperative complications were analyzed. RESULTS: A total of 309 patients were included, 193 (62.5%) in Group B, and 116 (37.5%) in Group D, with an age of 9.2 ± 0.4 and 9.4 ± 0.6 years, respectively (CI = 95%). Diagnostic time was 1.35 and 1.43 days (p>0.05) in Groups B and D, respectively, with ≥ 3 days representing 15.5% of cases in Group B, and 16.4% of cases in Group D (p = 0.84). The proportion of complicated appendicitis was 23.3% in Group B vs. 21.6% in Group D (p>0.05). Postoperative complications were observed in 11.4% of patients in Group B, and in 13.8% of patients in Group D (p>0.05), with intra-abdominal abscess being the most frequent complication in both groups (54.5% of the total complications in Group B vs. 65.5% in Group D; p>0.05). CONCLUSIONS: The management of acute appendicitis and its complications in pediatric patients has not been impacted by the SARS-CoV-2 pandemic or the safety measures enforced.

INTRODUCCION: Se ha descrito el impacto de la pandemia del SARS-CoV-2 en la atención sanitaria, al suponer un aumento del retraso diagnóstico y morbilidad. Nuestro objetivo es evaluar su influencia en el desarrollo de complicaciones en las apendicitis agudas en niños. METODOLOGIA: Estudio retrospectivo de cohortes, incluyendo los pacientes menores de 15 años tratados por apendicitis aguda desde 01/01/2019 hasta 31/12/2020. Se distribuyeron según su fecha de diagnóstico en: antes de la pandemia (A) (enero/2019-febrero/2020) y durante la pandemia (P) (marzo-diciembre/2020). Según los hallazgos quirúrgicos se clasificaron en: apendicitis complicadas (perforadas/abscesos/plastrones/peritonitis) y no complicadas (catarrales/flemonosas/gangrenosas). Se analizaron datos demográficos, tiempo de evolución y complicaciones postoperatorias. RESULTADOS: Se incluyeron un total de 309 pacientes, 193 pacientes (62,5%) en el grupo A y 116 (37,5%) en el P, con edades de 9,2 ± 0,4 y 9,4 ± 0,6 años respectivamente (IC = 95%). Los días al diagnóstico fueron 1,35 y 1,43 (p>0,05) en A y P respectivamente, siendo ≥ 3 días en 15,5% de A y 16,4% en P (p = 0,84). La proporción de apendicitis complicada fue un 23,3% en A vs. 21,6% en P; con p>0,05. Se observaron complicaciones postoperatorias en 11,4% de A y 13,8% de P (p>0,05), siendo la más frecuente el absceso intraabdominal en ambos grupos (54,5% del total de complicaciones vs 65,5%; en A y P respectivamente; p>0,05). CONCLUSIONES: La atención sanitaria de la apendicitis aguda y sus complicaciones en pacientes pediátricos no se ha visto modificada por la pandemia del SARS-CoV-2 o las medidas de seguridad adoptadas durante la misma.

¿Han aumentado las complicaciones de las apendicitisagudas en niños por el impacto del SARS-CoV-2? / Have acute appendicitis complications increased in children as a result of SARS-CoV-2?

Introducción: Se ha descrito el impacto de la pandemia del SARS-CoV-2 en la atención sanitaria, al suponer un aumento del retraso diagnóstico y de la morbilidad. Nuestro objetivo es evaluar su influenciaen el desarrollo de complicaciones en las apendicitis agudas en niños. Metodología: Estudio retrospectivo de cohortes, incluyendo lospacientes menores de 15 años tratados por apendicitis aguda desde01/01/2019 hasta 31/12/2020. Se distribuyeron según su fecha dediagnóstico en: antes de la pandemia (A) (enero/2019-febrero/2020) ydurante la pandemia (P) (marzo-diciembre/2020). Según los hallazgosquirúrgicos se clasificaron en: apendicitis complicadas (perforadas/abscesos/plastrones/peritonitis) y no complicadas (catarrales/flemonosas/gangrenosas). Se analizaron datos demográficos, tiempo de evolucióny complicaciones postoperatorias. Resultados: Se incluyeron un total de 309 pacientes, 193 pacientes(62,5%) en el grupo A y 116 (37,5%) en el P, con edades de 9,2 ± 0,4y 9,4 ± 0,6 años respectivamente (IC = 95%). Los días al diagnósticofueron 1,35 y 1,43 (p > 0,05) en A y P respectivamente, siendo ≥ 3 díasen el 15,5% de A y el 16,4% en P (p = 0,84). La proporción de apendicitis complicada fue un 23,3% en A vs. un 21,6% en P; con p > 0,05.Se observaron complicaciones postoperatorias en un 11,4% de A y un 13,8% de P (p > 0,05), siendo la más frecuente el absceso intraabdominalen ambos grupos (54,5% del total de complicaciones vs. 65,5%, en Ay P respectivamente; p > 0,05). Conclusiones: La atención sanitaria de la apendicitis aguda y suscomplicaciones en pacientes pediátricos no se ha visto modificada por la pandemia del SARS-CoV-2 o las medidas de seguridad adoptadasdurante la misma.(AU)

Introduction: The impact of the SARS-CoV-2 pandemic on health-care has already been described, since it has caused an increase in diagnostic delay and morbidity. Our objective was to assess its influence on the development of complications in children with acute appendicitis. Materials and methods: A retrospective cohort study was carriedout. It included acute appendicitis patients under 15 years of age treatedfrom January 1, 2019 to December 31, 2020. They were classified according to diagnosis date as before the pandemic (B) (January 2019-February2020) and during the pandemic (D) (March 2020-December 2020). According to operative findings, they were classified as complicated appendicitis (perforated/abscess/plastron/peritonitis) and non-complicatedappendicitis (catarrhal/phlegmonous/gangrenous). Demographic data,progression time, and postoperative complications were analyzed. Results: A total of 309 patients were included, 193 (62.5%) inGroup B, and 116 (37.5%) in Group D, with an age of 9.2 ± 0.4 and9.4 ± 0.6 years, respectively (CI = 95%). Diagnostic time was 1.35 and1.43 days (p > 0.05) in Groups B and D, respectively, with ≥ 3 daysrepresenting 15.5% of cases in Group B, and 16.4% of cases in GroupD (p = 0.84). The proportion of complicated appendicitis was 23.3% inGroup B vs. 21.6% in Group D (p > 0.05). Postoperative complicationswere observed in 11.4% of patients in Group B, and in 13.8% of patientsin Group D (p > 0.05), with intrabdominal abscess being the mostfrequent complication in both groups (54.5% of the total complicationsin Group B vs. 65.5% in Group D; p > 0.05). Conclusions: The management of acute appendicitis and its complications in pediatric patients has not been impacted by the SARS-CoV-2pandemic or the safety measures enforced.(AU)

Fracturas metafisarias de tibia distal: analisis comparativo de los resultados obtenidos mediante placa bloqueada y clavo intramedular / Metaphysary fractures of the distal tibia: Comparative analysis of the results obtained by means of a blocked plate and intramedular nail

Introducción Las fracturas del tercio distal de tibia son en su mayoría consecuencia de un traumatismo de alta energía con importante afectación de partes blandas siendo mas frecuentes en varones. Este tipo de fracturas se diferencian de la fractura articular de pilón tibial en su mecanismo de lesión, manejo y pronóstico. El objetivo del presente estudio fue analizar y comparar los resultados obtenidos en el tratamiento de las fracturas de tercio distal de tibia sin extensión articular mediante placa bloqueada y clavo intramedular. Material y métodos: Realizamos un estudio retrospectivo en el que se incluyeron todos los pacientes con diagnostico «fractura de tercio distal de tibia» segmento 43A según la clasificación propuesta por «Trauma Orthopedic Association» intervenidos entre enero del 2015 y mayo del 2019. Obtuvimos 24 pacientes intervenidos mediante clavo intramedular y 29 mediante placa bloqueada. Resultados: La muestra incluyó 53 pacientes (36 varones y 17 mujeres) con una media de edad de 51 años (rango: 15-77 años). El tiempo de seguimiento medio fue de 6 meses (3-30 meses). No se hallaron diferencias significativas en el tiempo de consolidación de la fractura, aunque el inicio de la deambulación con carga fue mas temprano en el grupo clavo. Discusión: En la actualidad no existe consenso acerca del manejo terapeútico de las fracturas distales de tibia sin extensión articular. Conclusiones: Dados los resultados obtenidos consideramos que tanto la osteosíntesis con clavo intramedular como con placa bloqueada son opciones válidas en el tratamiento de las fracturas del tercio distal de tibia.(AU)

Introduction: Fractures of the distal third of the tibia are mostly the consequence of high-energy trauma with significant soft tissue involvement, being more frequent in men.These types of fractures differ from the tibial pilon joint fracture in their mechanism of injury, management and prognosis. The objective of the present study was to analyze and compare the results obtained in the treatment of fractures of the distal third of the tibia without joint extension using a locked plate and intramedullary nail. Material and methods: We carried out a retrospective study with patients diagnosed of “distal third tibia fracture” segment 43A according to the classification proposed by the “Trauma Orthopedic Association” who were intervened between January 2015 and May 2019 were included. We obtained 24 patients intervened with a nail intramedullary and 29 using a blocked plate. Results: The study included 53 patients, 36 men and 17 women with a mean age of 51 years (range: 15-77 years). The mean follow-up time was 6 months (3–30 months). No significant differences were found in the time to fracture healing, although the beginning with load walking was earlier in the nail group. Discussion: Currently there is no consensus on the therapeutic management of distal tibia fractures without joint extension. Conclusions: After analyzing the results, we consider that both intramedullary nail osteosynthesis and a locked plate are valid options in the treatment of fractures of the distal third of the tibia.(AU)

Metaphysary fractures of the distal tibia: Comparative analysis of the results obtained by means of a blocked plate and intramedular nail / Fracturas metafisarias de tibia distal: Análisis comparativo de los resultados obtenidos mediante placa bloqueada y clavo intramedular

Introduction: Fractures of the distal third of the tibia are mostly the consequence of high-energy trauma with significant soft tissue involvement, being more frequent in men.These types of fractures differ from the tibial pilon joint fracture in their mechanism of injury, management and prognosis. The objective of the present study was to analyze and compare the results obtained in the treatment of fractures of the distal third of the tibia without joint extension using a locked plate and intramedullary nail. Material and methods: We carried out a retrospective study with patients diagnosed of “distal third tibia fracture” segment 43A according to the classification proposed by the “Trauma Orthopedic Association” who were intervened between January 2015 and May 2019 were included. We obtained 24 patients intervened with a nail intramedullary and 29 using a blocked plate. Results: The study included 53 patients, 36 men and 17 women with a mean age of 51 years (range: 15-77 years). The mean follow-up time was 6 months (3–30 months). No significant differences were found in the time to fracture healing, although the beginning with load walking was earlier in the nail group. Discussion: Currently there is no consensus on the therapeutic management of distal tibia fractures without joint extension. Conclusions: After analyzing the results, we consider that both intramedullary nail osteosynthesis and a locked plate are valid options in the treatment of fractures of the distal third of the tibia.(AU)

Introducción Las fracturas del tercio distal de tibia son en su mayoría consecuencia de un traumatismo de alta energía con importante afectación de partes blandas siendo mas frecuentes en varones. Este tipo de fracturas se diferencian de la fractura articular de pilón tibial en su mecanismo de lesión, manejo y pronóstico. El objetivo del presente estudio fue analizar y comparar los resultados obtenidos en el tratamiento de las fracturas de tercio distal de tibia sin extensión articular mediante placa bloqueada y clavo intramedular. Material y métodos: Realizamos un estudio retrospectivo en el que se incluyeron todos los pacientes con diagnostico «fractura de tercio distal de tibia» segmento 43A según la clasificación propuesta por «Trauma Orthopedic Association» intervenidos entre enero del 2015 y mayo del 2019. Obtuvimos 24 pacientes intervenidos mediante clavo intramedular y 29 mediante placa bloqueada. Resultados: La muestra incluyó 53 pacientes (36 varones y 17 mujeres) con una media de edad de 51 años (rango: 15-77 años). El tiempo de seguimiento medio fue de 6 meses (3-30 meses). No se hallaron diferencias significativas en el tiempo de consolidación de la fractura, aunque el inicio de la deambulación con carga fue mas temprano en el grupo clavo. Discusión: En la actualidad no existe consenso acerca del manejo terapeútico de las fracturas distales de tibia sin extensión articular. Conclusiones: Dados los resultados obtenidos consideramos que tanto la osteosíntesis con clavo intramedular como con placa bloqueada son opciones válidas en el tratamiento de las fracturas del tercio distal de tibia.(AU)

Total reverse arthroplasty of the shoulder and structural bone graft in glenoid defects: Short-term results. / Artroplastia total inversa de hombro e injerto óseo estructural en defectos glenoideos: resultados a corto plazo.

OBJECTIVE: To evaluate the clinical and radiological results of a series of patients with a glenoid bone defect treated by reverse total shoulder arthroplasty associated with a bone graft stabilized with a trabecular titanium glenoid component (Axioma SMR Lima®). MATERIAL AND METHODS: Retrospective descriptive study of 16 consecutive patients with an average age of 68.2years. In 13 cases they were primary arthroplasties and in 3 revision ones. The data included in the study were obtained by reviewing the clinical history. The glenoid defect was classified according to Gupta et al. The pre- and postoperative clinical assessment included the score on the visual analogue pain scale (VAS), the result of the Constant score and the active joint balance. Radiographically, the integration of the bone graft and the fixation of the components were assessed. RESULTS: The average follow-up was 42.1months. The average VAS score improved from 7.5 preoperative points to 2.5 points in the last control (P=.006) and on the Constant score from 35.8 pre-surgical points to 64.4 points (P=.001). The average joint balance went from 54° of abduction, 54° of antepulsion, 24° of external rotation and internal rotation to preoperative trochanter to 120° of abduction (P=.001), 124° of antepulsion (P=.001), 63° of external rotation (P=0.001) and internal rotation at L5 in the last clinical control. In all patients, graft integration and the absence of component loosening were observed. The incidence of complications was 6.2%. DISCUSSION: The treatment of glenoid defects by reverse total shoulder arthroplasty and a bone graft stabilized by trabecular titanium metaglene presents good clinical and radiological results and a low rate of short-term complications.

Artroplastia total inversa de hombro e injerto óseo estructural en defectos glenoideos: resultados a corto plazo / Total reverse arthroplasty of the shoulder and structural bone graft in glenoid defects: Short-term results

Objetivo: Evaluar los resultados clínicos y radiológicos de una serie de pacientes con defecto óseo glenoideo tratados mediante artroplastia total inversa de hombro asociada a injerto óseo estabilizado mediante componente glenoideo de titanio trabecular (Axioma SMR Lima®). Material y métodos: Estudio descriptivo retrospectivo de 16 pacientes consecutivos con una edad media de 68,2años. En 13 casos se trataba de artroplastias primarias y en 3, de revisión. Los datos incluidos en el estudio se obtuvieron mediante revisión de la historia clínica. El defecto glenoideo se clasificó de acuerdo con Gupta et al. La valoración clínica pre- y postoperatoria incluyó la puntuación en la escala visual analógica de dolor (EVA), el resultado de la escala Constant y el balance articular activo. Radiográficamente se valoró la integración del injerto óseo y la fijación de los componentes. Resultados: El seguimiento medio fue de 42,1meses. La puntuación media en la escala EVA mejoró de 7,5 puntos preoperatorios a 2,5 puntos en el último control (p=0,006) y en la escala de Constant de 35,8 puntos prequirúrgicos a 64,4 puntos (p=0,001). El balance articular activo pasó de 54° de abducción, 54° de antepulsión, 24° de rotación externa y rotación interna a trocánter preoperatorios a 120° abducción (p=0,001), 124° antepulsión (p=0,001), 63° rotación externa (p=0,001) y rotación interna a L5 en el último control clínico. En todos los pacientes se objetivó integración del injerto y la ausencia de aflojamiento de los componentes. La incidencia de complicaciones fue del 6,2%. Discusión: El tratamiento de defectos glenoideos mediante artroplastia inversa e injerto óseo estabilizado mediante metaglena de titanio trabecular presenta buenos resultados clínicos, radiológicos y una baja tasa de complicaciones a corto plazo.(AU)

Objective: To evaluate the clinical and radiological results of a series of patients with a glenoid bone defect treated by reverse total shoulder arthroplasty associated with a bone graft stabilized with a trabecular titanium glenoid component (Axioma SMR Lima®). Material and methods: Retrospective descriptive study of 16 consecutive patients with an average age of 68.2years. In 13 cases they were primary arthroplasties and in 3 revision ones. The data included in the study were obtained by reviewing the clinical history. The glenoid defect was classified according to Gupta et al. The pre- and postoperative clinical assessment included the score on the visual analogue pain scale (VAS), the result of the Constant score and the active joint balance. Radiographically, the integration of the bone graft and the fixation of the components were assessed. Results: The average follow-up was 42.1months. The average VAS score improved from 7.5 preoperative points to 2.5 points in the last control (P=.006) and on the Constant score from 35.8 pre-surgical points to 64.4 points (P=.001). The average joint balance went from 54° of abduction, 54° of antepulsion, 24° of external rotation and internal rotation to preoperative trochanter to 120° of abduction (P=.001), 124° of antepulsion (P=.001), 63° of external rotation (P=0.001) and internal rotation at L5 in the last clinical control. In all patients, graft integration and the absence of component loosening were observed. The incidence of complications was 6.2%. Discussion: The treatment of glenoid defects by reverse total shoulder arthroplasty and a bone graft stabilized by trabecular titanium metaglene presents good clinical and radiological results and a low rate of short-term complications.(AU)

Total reverse arthroplasty of the shoulder and structural bone graft in glenoid defects: Short-term results / Artroplastia total inversa de hombro e injerto óseo estructural en defectos glenoideos: resultados a corto plazo

Objective: To evaluate the clinical and radiological results of a series of patients with a glenoid bone defect treated by reverse total shoulder arthroplasty associated with a bone graft stabilized with a trabecular titanium glenoid component (Axioma SMR Lima®). Material and methods: Retrospective descriptive study of 16 consecutive patients with an average age of 68.2years. In 13 cases they were primary arthroplasties and in 3 revision ones. The data included in the study were obtained by reviewing the clinical history. The glenoid defect was classified according to Gupta et al. The pre- and postoperative clinical assessment included the score on the visual analogue pain scale (VAS), the result of the Constant score and the active joint balance. Radiographically, the integration of the bone graft and the fixation of the components were assessed. Results: The average follow-up was 42.1months. The average VAS score improved from 7.5 preoperative points to 2.5 points in the last control (P=.006) and on the Constant score from 35.8 pre-surgical points to 64.4 points (P=.001). The average joint balance went from 54° of abduction, 54° of antepulsion, 24° of external rotation and internal rotation to preoperative trochanter to 120° of abduction (P=.001), 124° of antepulsion (P=.001), 63° of external rotation (P=0.001) and internal rotation at L5 in the last clinical control. In all patients, graft integration and the absence of component loosening were observed. The incidence of complications was 6.2%. Discussion: The treatment of glenoid defects by reverse total shoulder arthroplasty and a bone graft stabilized by trabecular titanium metaglene presents good clinical and radiological results and a low rate of short-term complications.(AU)

Objetivo: Evaluar los resultados clínicos y radiológicos de una serie de pacientes con defecto óseo glenoideo tratados mediante artroplastia total inversa de hombro asociada a injerto óseo estabilizado mediante componente glenoideo de titanio trabecular (Axioma SMR Lima®). Material y métodos: Estudio descriptivo retrospectivo de 16 pacientes consecutivos con una edad media de 68,2años. En 13 casos se trataba de artroplastias primarias y en 3, de revisión. Los datos incluidos en el estudio se obtuvieron mediante revisión de la historia clínica. El defecto glenoideo se clasificó de acuerdo con Gupta et al. La valoración clínica pre- y postoperatoria incluyó la puntuación en la escala visual analógica de dolor (EVA), el resultado de la escala Constant y el balance articular activo. Radiográficamente se valoró la integración del injerto óseo y la fijación de los componentes. Resultados: El seguimiento medio fue de 42,1meses. La puntuación media en la escala EVA mejoró de 7,5 puntos preoperatorios a 2,5 puntos en el último control (p=0,006) y en la escala de Constant de 35,8 puntos prequirúrgicos a 64,4 puntos (p=0,001). El balance articular activo pasó de 54° de abducción, 54° de antepulsión, 24° de rotación externa y rotación interna a trocánter preoperatorios a 120° abducción (p=0,001), 124° antepulsión (p=0,001), 63° rotación externa (p=0,001) y rotación interna a L5 en el último control clínico. En todos los pacientes se objetivó integración del injerto y la ausencia de aflojamiento de los componentes. La incidencia de complicaciones fue del 6,2%. Discusión: El tratamiento de defectos glenoideos mediante artroplastia inversa e injerto óseo estabilizado mediante metaglena de titanio trabecular presenta buenos resultados clínicos, radiológicos y una baja tasa de complicaciones a corto plazo.(AU)

Metaphysary fractures of the distal tibia: Comparative analysis of the results obtained by means of a blocked plate and intramedular nail. / Fracturas metafisarias de tibia distal: analisis comparativo de los resultados obtenidos mediante placa bloqueada y clavo intramedular.

INTRODUCTION: Fractures of the distal third of the tibia are mostly the consequence of high-energy trauma with significant soft tissue involvement, being more frequent in men. These types of fractures differ from the tibial pilon joint fracture in their mechanism of injury, management and prognosis. The objective of the present study was to analyze and compare the results obtained in the treatment of fractures of the distal third of the tibia without joint extension using a locked plate and intramedullary nail. MATERIAL AND METHODS: We carried out a retrospective study with patients diagnosed of "distal third tibia fracture" segment 43A according to the classification proposed by the "Trauma Orthopedic Association" who were intervened between January 2015 and May 2019 were included. We obtained 24 patients intervened with a nail intramedullary and 29 using a blocked plate. RESULTS: The study included 53 patients, 36 men and 17 women with a mean age of 51 years (range: 15-77 years). The mean follow-up time was 6 months (3-30 months). No significant differences were found in the time to fracture healing, although the beginning with load walking was earlier in the nail group. DISCUSSION: Currently there is no consensus on the therapeutic management of distal tibia fractures without joint extension. CONCLUSIONS: After analyzing the results, we consider that both intramedullary nail osteosynthesis and a locked plate are valid options in the treatment of fractures of the distal third of the tibia.