ABSTRACT
Henoch Schonlein purpura (HSP) is a common childhood vasculitis, characterized by a non-thrombocytopenic palpable purpura and systemic features. It can be triggered by conditions like infections and insect bites. We present the case of a six-year-old girl with palpable maculopapular lesions on the lower limbs, itching, mild pain, swelling of feet, limitation of limb mobility, and a history of bee sting. Thigh skin biopsy was performed, with a report of leucocytoclastic vasculitis, and was diagnosed as HSP. She was prescribed bed rest, and was given oral hydration. The patient outcome was favorable and was discharged after five days. This is the fifth report of a HSP case associated with a bee sting with an uncomplicated course, which is in contrast to previous case reports.
La púrpura de Henoch Schonlein es una vasculitis común en la infancia, caracterizada por una púrpura palpable no trombocitopénica y manifestaciones sistémicas. Está relacionada con patologías desencadenantes como las infecciones y las picaduras de insectos. Presentamos el caso de una escolar de 6 años, de sexo femenino, con lesiones maculopapulares palpables en miembros inferiores, prurito, dolor leve, edema de pies, limitación al movimiento y antecedente de picadura de abeja. Se realizó biopsia cutánea de muslo con reporte de vasculitis leucocitoclástica y se diagnosticó como púrpura de Henoch Schonlein. Se indicó reposo y se le administró hidratación oral. Evolucionó favorablemente y fue dada de alta a los cinco días. Este es el quinto caso de púrpura de Henoch Schonlein asociado a picadura de abeja, la que se presentó sin complicaciones a diferencia de los reportes de caso previos.
Subject(s)
IgA Vasculitis/etiology , Insect Bites and Stings/complications , Vasculitis, Leukocytoclastic, Cutaneous/etiology , Animals , Bees , Biopsy , Child , Female , Humans , IgA Vasculitis/diagnosis , Pain/etiology , Vasculitis, Leukocytoclastic, Cutaneous/diagnosisABSTRACT
The vasculities are complex diseases. Their cutaneous manifestations are very important and often mirror several pathologies. Cocaine use has been related to both, vasculitis and thrombotic vasculopathy and pseudovasculitis. A new syndrome has been described in association with its adulteration with levamisole. It can be very serious, leading patients to death. This is relevant as levamisole-adultered cocaine seems to be increasingly offered to consumers. Our goal is to report the first two cases in Mexico, which faces an important raise in cocaine use, emphasizing that a high suspicion based on certain characteristics allows for early recognition and adequate treatment.
Las vasculitis son enfermedades complejas con manifestaciones cutáneas importantes que pueden traducir diversas patologías. El uso de cocaína está relacionado con casos tanto de vasculitis y vasculopatía trombótica, como de pseudovasculitis. Recientemente se ha descrito una condición peculiar asociada a su forma adulterada con levamisol, la cual puede ser incluso mortal, y cuya frecuencia va en aumento. Nuestro objetivo es reportar los primeros dos casos de alta sospecha en México, que enfrenta un incremento en el consumo de cocaína, enfatizando en que ciertas características y la realización de determinados estudios permiten la identificación temprana y el tratamiento adecuado de esta condición.
Subject(s)
Cocaine/chemistry , Drug Contamination , Illicit Drugs/chemistry , Illicit Drugs/toxicity , Levamisole/toxicity , Thrombosis/chemically induced , Vasculitis/chemically induced , Adult , Capillaries/drug effects , Humans , Male , Mexico , Skin/blood supply , Thrombosis/diagnosis , Vasculitis/diagnosisSubject(s)
Humans , Male , Adult , Female , Young Adult , Aged , Mycetoma , Mycetoma/diagnosis , Mycetoma/pathology , Mycetoma/therapy , PeruABSTRACT
We present the case of a 23-year-old woman who was referred with an 18-month history, of oral ulcers finally diagnosed as erythema multiforme (EM). During this time she received multiple diagnoses and treatments, without resolution of the symptoms. The patient had a history of frequent infections by herpes simplex virus (HSV) in mouth, and apparently the drugs used to control it extended the signs and symptoms of EM. The patient showed rapid improvement after discontinuation of the drugs, and treatment for episodes of HSV infection was prescribed.
