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1.
Vertex ; 25(114): 92-8, 2014.
Article in Spanish | MEDLINE | ID: mdl-25153974

ABSTRACT

OBJECTIVE: To assess if there are changes in brain hemodynamics evaluated by means of transcranial doppler's flow velocity, pulsatile index and cerebral perfusion pressure, between cocaine chronic abusers and healthy volunteers. METHOD: Prospective, case and control, observational study. Sex, age, user history, vital signs and transcranial doppler findings.Statistical analysis was performed by means of normality test, Wilcoxon's test for non parametric samples and T Student test. RESULTS: Fifty-three abusers and 35 healthy volunteers were studied. Statistical differences were found for a diminish in age(p=0.008) and cerebral perfusion pressure in all cerebral arteries (p

Subject(s)
Brain/blood supply , Cocaine-Related Disorders/physiopathology , Cocaine/pharmacology , Dopamine Uptake Inhibitors/pharmacology , Hemodynamics/drug effects , Adolescent , Adult , Case-Control Studies , Chronic Disease , Female , Humans , Male , Middle Aged , Prospective Studies , Young Adult
2.
Vertex rev. argent. psiquiatr ; 25(114): 92-8, 2014 Mar-Apr.
Article in Spanish | LILACS, BINACIS | ID: biblio-1176971

ABSTRACT

OBJECTIVE: To assess if there are changes in brain hemodynamics evaluated by means of transcranial doppler’s flow velocity, pulsatile index and cerebral perfusion pressure, between cocaine chronic abusers and healthy volunteers. METHOD: Prospective, case and control, observational study. Sex, age, user history, vital signs and transcranial doppler findings.Statistical analysis was performed by means of normality test, Wilcoxon’s test for non parametric samples and T Student test. RESULTS: Fifty-three abusers and 35 healthy volunteers were studied. Statistical differences were found for a diminish in age(p=0.008) and cerebral perfusion pressure in all cerebral arteries (p

Subject(s)
Cocaine/pharmacology , Brain/blood supply , Hemodynamics/drug effects , Dopamine Uptake Inhibitors/pharmacology , Cocaine-Related Disorders/physiopathology , Adolescent , Adult , Young Adult , Chronic Disease , Prospective Studies , Case-Control Studies , Female , Humans , Male , Middle Aged
3.
Vertex ; 25(114): 92-8, 2014 Mar-Apr.
Article in Spanish | BINACIS | ID: bin-133413

ABSTRACT

OBJECTIVE: To assess if there are changes in brain hemodynamics evaluated by means of transcranial dopplers flow velocity, pulsatile index and cerebral perfusion pressure, between cocaine chronic abusers and healthy volunteers. METHOD: Prospective, case and control, observational study. Sex, age, user history, vital signs and transcranial doppler findings.Statistical analysis was performed by means of normality test, Wilcoxons test for non parametric samples and T Student test. RESULTS: Fifty-three abusers and 35 healthy volunteers were studied. Statistical differences were found for a diminish in age(p=0.008) and cerebral perfusion pressure in all cerebral arteries (p

Subject(s)
Brain/blood supply , Cocaine-Related Disorders/physiopathology , Cocaine/pharmacology , Dopamine Uptake Inhibitors/pharmacology , Hemodynamics/drug effects , Adolescent , Adult , Case-Control Studies , Chronic Disease , Female , Humans , Male , Middle Aged , Prospective Studies , Young Adult
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