ABSTRACT
OBJECTIVE: The aim is to highlight three cases of focal spasticity and/or dystonia as potential noxious triggers and treatment targets of Paroxysmal Sympathetic Hyperactivity (PSH). METHODS: We review the literature, explore pathophysiology, and review treatment options. We discuss the clinical course and management of three unique patients who presented to a teaching hospital with severe traumatic brain injury (TBI) complicated by PSH managed by a physiatry consult team. RESULTS: Three patients, ranging in age from 8 months to 27 years, were admitted with severe TBI complicated by PSH refractory to pharmacologic management. All three patients, however, had resolution of PSH within 24-72 hours of focal spasticity treatments (i.e. casting and botulinum toxin injections). CONCLUSION: PSH is a constellation of physiologic findings and physical symptoms that is incompletely understood. Management is based on addressing predominant symptom features and physiologic responses. In certain cases, ongoing spasticity and/or dystonia may serve as noxious stimuli for persistence of PSH in moderate to severe brain injury. As such, the focal treatment of spasticity and/or dystonia may be considered as a treatment target in the management of refractory PSH.
Subject(s)
Autonomic Nervous System Diseases , Brain Injuries, Traumatic , Dystonia , Dystonic Disorders , Autonomic Nervous System Diseases/etiology , Brain Injuries, Traumatic/complications , Brain Injuries, Traumatic/therapy , Dystonia/drug therapy , Dystonia/etiology , Dystonic Disorders/etiology , Dystonic Disorders/therapy , Humans , Muscle Spasticity/drug therapy , Muscle Spasticity/etiology , Psychomotor AgitationABSTRACT
BACKGROUND: Maximizing long-term recovery following traumatic brain injury (TBI) is an important end point. We hypothesized that the addition of a dedicated physiatrist specializing in brain injury medicine to the trauma team would lead to improved functional outcomes. METHODS: Data from the Northern NJ TBI Model Systems were queried for all patients admitted to rehabilitation from four regional trauma centers, one with a full-time TBI physiatrist (PHYS) and three without (NO-PHYS). Patient demographics, mechanism of injury, Glasgow Coma Scale (GCS) score, length of posttraumatic amnesia, length of stay, and Functional Independence Measure (FIM) were abstracted. TBI severity was determined by GCS score and length of posttraumatic amnesia. FIM motor and cognitive scores at rehabilitation admission and discharge were the primary outcome measure. TBI medications (stimulants, sleep, and neurodepressants) administered in acute care were reviewed to evaluate prescription patterns. RESULTS: A total of 148 patients treated at four trauma centers and discharged to a single acute inpatient rehabilitation center between 2005 to 2013 were divided into two groups, PHYS with 44 patients and NO-PHYS with 104 patients. Compared with those in the NO-PHYS group, patients from the PHYS group had significant improvement in FIM motor and cognitive scores (p < 0.05). Prescription patterns differed. Patients from the PHYS group received significantly more neurostimulants (p < 0.001) and sleep medications (p = 0.02) compared with the NO-PHYS group. Analysis of covariance was conducted to examine FIM (motor and cognitive) changes from rehabilitation admission to discharge based on medications initiated in acute care. Those who received neither a neurostimulant nor a sleep medication had significantly lower FIM motor scores compared with those who received at least one of these medications (p = 0.047) and compared with those who received both types of medication (p = 0.17). No significant differences were found in FIM cognitive scores. CONCLUSION: The addition of a dedicated physiatrist providing early specialized care to patients who sustained a moderate or severe TBI was associated with improved functional outcomes upon discharge from rehabilitation. The presence of a dedicated trauma center physiatrist, trained in TBI rehabilitation, was also associated with a change in neuroprotective medication management in the acute care setting. LEVEL OF EVIDENCE: Therapeutic study, level IV.
Subject(s)
Brain Injuries/rehabilitation , Physical and Rehabilitation Medicine , Rehabilitation Centers , Disability Evaluation , Female , Glasgow Coma Scale , Humans , Injury Severity Score , Length of Stay , Male , Middle Aged , New Jersey , Quality Improvement , Recovery of Function , Trauma Centers , WorkforceABSTRACT
The United States economy entered a recession in December 2007. This study aims to determine whether the utilization of elective orthopedic surgeries has been impacted by this recession. From January 2007 to December 2009 at a single private practice in New Jersey, 4820 total joint replacement procedures were scheduled, of which 649 of those were cancelled. The rate of cancellation for financial reasons was compared to multiple economic measures by linear regression analysis. The results show that the rate of financially motivated cancellations increased over time concurring with multiple financial markers reflecting the economic recession. The results suggest that the recession has created a financial barrier for a significant number of Americans, leading to decreased utilization of care. While there was a statistically significant increase in cancellations for financial reasons, the overall rate of cancellations in the total joint population is still low, representing only about 1% of all cases.
