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Vopr Med Khim ; 34(4): 109-12, 1988.
Article in Russian | MEDLINE | ID: mdl-3195124

ABSTRACT

A new derivative of diprophylline--[2-hydroxy-3(theophylline-7-ol)] propyl ester 4-benzyloxybenzoic acid was shown to decrease the content of cholesterol and of atherogenic lipoproteins in blood serum of hyperlipidemic guinea pigs. In blood serum of rabbits the new substance studied decreased cholesterol, free fatty acids and malonic dialdehyde concentrations.


Subject(s)
Dyphylline/analogs & derivatives , Hypolipidemic Agents/pharmacology , Theophylline/analogs & derivatives , Animals , Clofibrate/pharmacology , Diet, Atherogenic , Dyphylline/pharmacology , Dyphylline/toxicity , Fatty Acids, Nonesterified/blood , Guinea Pigs , Hypolipidemic Agents/toxicity , Lipids/blood , Male , Malondialdehyde/blood , Rabbits
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