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1.
Sci Rep ; 8(1): 8653, 2018 06 05.
Article in English | MEDLINE | ID: mdl-29872137

ABSTRACT

Shale oil and gas exploitation by hydraulic fracturing experienced a strong development worldwide over the last years, accompanied by a substantial increase of related induced seismicity, either consequence of fracturing or wastewater injection. In Europe, unconventional hydrocarbon resources remain underdeveloped and their exploitation controversial. In UK, fracturing operations were stopped after the Mw 2.3 Blackpool induced earthquake; in Poland, operations were halted in 2017 due to adverse oil market conditions. One of the last operated well at Wysin, Poland, was monitored independently in the framework of the EU project SHEER, through a multidisciplinary system including seismic, water and air quality monitoring. The hybrid seismic network combines surface mini-arrays, broadband and shallow borehole sensors. This paper summarizes the outcomes of the seismological analysis of these data. Shallow artificial seismic noise sources were detected and located at the wellhead active during the fracturing stages. Local microseismicity was also detected, located and characterised, culminating in two events of Mw 1.0 and 0.5, occurring days after the stimulation in the vicinity of the operational well, but at very shallow depths. A sharp methane peak was detected ~19 hours after the Mw 0.5 event. No correlation was observed between injected volumes, seismicity and groundwater parameters.

2.
Science ; 360(6392): 1003-1006, 2018 06 01.
Article in English | MEDLINE | ID: mdl-29700226

ABSTRACT

The moment magnitude (Mw) 5.5 earthquake that struck South Korea in November 2017 was one of the largest and most damaging events in that country over the past century. Its proximity to an enhanced geothermal system site, where high-pressure hydraulic injection had been performed during the previous 2 years, raises the possibility that this earthquake was anthropogenic. We have combined seismological and geodetic analyses to characterize the mainshock and its largest aftershocks, constrain the geometry of this seismic sequence, and shed light on its causal factors. According to our analysis, it seems plausible that the occurrence of this earthquake was influenced by the aforementioned industrial activities. Finally, we found that the earthquake transferred static stress to larger nearby faults, potentially increasing the seismic hazard in the area.

4.
Chirurg ; 82(5): 442, 444-6, 2011 May.
Article in German | MEDLINE | ID: mdl-20967527

ABSTRACT

Acute aortic rupture is associated with a high mortality. The leading symptoms are chest pain, dyspnea and hemodynamic instability as well as hemoptysis. In the current case report a patient with known coronary artery disease and prior coronary artery bypass surgery presented with hemoptysis. He was initially treated for a presumed gastroenterological disorder. The chest X-ray delineated a structure suggestive of aortic rupture and this diagnosis was confirmed by computed tomography. Emergency treatment was performed by implantation of an endovascular stent prosthesis. This procedure is currently regarded the standard treatment of rupture of the descending thoracic aorta. We conclude our case report with a discussion of epidemiology, symptoms, pathogenesis and therapy of this clinically dramatic disease.


Subject(s)
Aortic Aneurysm, Thoracic/complications , Aortic Aneurysm, Thoracic/diagnosis , Aortic Rupture/complications , Aortic Rupture/diagnosis , Hemoptysis/etiology , Acute Disease , Angiography, Digital Subtraction , Angioplasty/methods , Aortic Aneurysm, Thoracic/therapy , Aortic Rupture/therapy , Aortic Valve/surgery , Aortography , Blood Vessel Prosthesis Implantation , Coronary Artery Bypass , Diagnosis, Differential , Heart Valve Prosthesis Implantation , Humans , Image Processing, Computer-Assisted , Male , Middle Aged , Mitral Valve/surgery , Postoperative Complications/diagnosis , Postoperative Complications/therapy , Prosthesis Design , Stents , Tomography, X-Ray Computed
5.
Phys Rev Lett ; 104(23): 237001, 2010 Jun 11.
Article in English | MEDLINE | ID: mdl-20867262

ABSTRACT

We demonstrate that in a d-wave superconductor the bulk nonlinear Meissner effect is dominated by a surface effect due to Andreev bound states at low temperatures. The contribution of this surface effect to the nonlinear response coefficient follows a 1/T3 law with the opposite sign compared to the bulk 1/T behavior. The crossover from bulk dominated behavior to surface dominated behavior occurs at a temperature of T/Tc∼1/square root(κ). We present an approximate analytical calculation, which supports our numerical calculations and provides a qualitative understanding of the effect. The effect can be probed by intermodulation distortion experiments.

6.
Phys Rev Lett ; 100(3): 037002, 2008 Jan 25.
Article in English | MEDLINE | ID: mdl-18233026

ABSTRACT

We study the influence of surface Andreev bound states in d-wave superconductors on the Bean-Livingston surface barrier for entry of a vortex line into a strongly type-II superconductor. Starting from Eilenberger theory, we derive a generalization of London theory to incorporate the anomalous surface currents arising from the Andreev bound states. This allows us to find an analytical expression for the modification of the Bean-Livingston barrier in terms of a single parameter describing the influence of the Andreev bound states. We find that the field of first vortex entry is significantly enhanced. Also, the depinning field for vortices near the surface is renormalized. Both effects are temperature dependent and depend on the orientation of the surface relative to the d-wave gap.

7.
Vasa ; 33(2): 93-6, 2004 May.
Article in German | MEDLINE | ID: mdl-15224463

ABSTRACT

A 30-year old man with pain in the right calf was submitted. Typical cardiovascular risk factors were excluded. Contrast enhanced MR-angiography at rest showed occlusion of right popliteal artery with collateral vessels due to an abnormal origin of medial head of gastrocnemius muscle at femoral diaphysis. In contrast to a normal MR-angiography at rest the exercise test detected a lateral deviation and a severe functional stenosis of the left popliteal artery. This was caused by an abnormal medial origin of medial head of gastrocnemius muscle at the inner femoral condylus. The patient has been treated with vascular reconstruction combined with myectomy on the right side and with myectomy only on the left side. These findings showed two different types of popliteal artery entrapment syndrome in one patient. MRI is able to detect the different types especially in different stages. Irreversible damages of popliteal artery in early diagnosed stages may thereby be prevented.


Subject(s)
Arterial Occlusive Diseases/diagnosis , Arterial Occlusive Diseases/surgery , Exercise Test , Magnetic Resonance Angiography/methods , Popliteal Artery/pathology , Popliteal Artery/surgery , Adult , Diagnosis, Differential , Humans , Lower Extremity/blood supply , Male , Muscle, Skeletal/abnormalities , Muscle, Skeletal/surgery , Syndrome
8.
Phys Rev Lett ; 93(24): 247001, 2004 Dec 10.
Article in English | MEDLINE | ID: mdl-15697848

ABSTRACT

At the surface of a d-wave superconductor, a zero-energy peak in the quasiparticle spectrum can be observed. This peak appears due to Andreev bound states and is maximal if the nodal direction of the d-wave pairing potential is perpendicular to the boundary. We examine the effect of a single Abrikosov vortex in front of a reflecting boundary on the zero-energy density of states. We can clearly see a splitting of the low-energy peak and therefore a suppression of the zero-energy density of states in a shadowlike region extending from the vortex to the boundary. This effect is stable for different models of the single Abrikosov vortex, for different mean free paths and also for different distances between the vortex center and the boundary. This observation promises to have also a substantial influence on the differential conductance and the tunneling characteristics for low excitation energies.

9.
Phys Rev Lett ; 91(12): 127006, 2003 Sep 19.
Article in English | MEDLINE | ID: mdl-14525394

ABSTRACT

The temperature dependence of the real part of the microwave complex conductivity at 17.9 GHz obtained from surface impedance measurements of two c-axis oriented MgB2 thin films reveals a pronounced maximum at a temperature around 0.6 times the critical temperature. Calculations in the frame of a two-band model based on Bardeen-Cooper-Schrieffer (BCS) theory suggest that this maximum corresponds to an anomalous coherence peak resembling the two-gap nature of MgB2. Our model assumes there is no interband impurity scattering and a weak interband pairing interaction, as suggested by band structure calculations. In addition, the observation of a coherence peak indicates that the pi band is in the dirty limit and dominates the total conductivity of our films.

10.
Phys Rev Lett ; 91(1): 017001, 2003 Jul 04.
Article in English | MEDLINE | ID: mdl-12906565

ABSTRACT

Recent measurements of the anisotropy of the upper critical field B(c2) on MgB2 single crystals have shown a puzzling strong temperature dependence. Here, we present a calculation of the upper critical field based on a detailed modeling of band structure calculations that takes into account both the unusual Fermi surface topology and the two gap nature of the superconducting order parameter. Our results show that the strong temperature dependence of the B(c2) anisotropy can be understood as an interplay of the dominating gap on the sigma band, which possesses a small c-axis component of the Fermi velocity, with the induced superconductivity on the pi-band possessing a large c-axis component of the Fermi velocity. We provide analytic formulas for the anisotropy ratio at T=0 and T=T(c) and quantitatively predict the distortion of the vortex lattice based on our calculations.

11.
Mol Biol Cell ; 12(5): 1481-98, 2001 May.
Article in English | MEDLINE | ID: mdl-11359937

ABSTRACT

To quantitatively investigate the trafficking of the transmembrane lectin VIP36 and its relation to cargo-containing transport carriers (TCs), we analyzed a C-terminal fluorescent-protein (FP) fusion, VIP36-SP-FP. When expressed at moderate levels, VIP36-SP-FP localized to the endoplasmic reticulum, Golgi apparatus, and intermediate transport structures, and colocalized with epitope-tagged VIP36. Temperature shift and pharmacological experiments indicated VIP36-SP-FP recycled in the early secretory pathway, exhibiting trafficking representative of a class of transmembrane cargo receptors, including the closely related lectin ERGIC53. VIP36-SP-FP trafficking structures comprised tubules and globular elements, which translocated in a saltatory manner. Simultaneous visualization of anterograde secretory cargo and VIP36-SP-FP indicated that the globular structures were pre-Golgi carriers, and that VIP36-SP-FP segregated from cargo within the Golgi and was not included in post-Golgi TCs. Organelle-specific bleach experiments directly measured the exchange of VIP36-SP-FP between the Golgi and endoplasmic reticulum (ER). Fitting a two-compartment model to the recovery data predicted first order rate constants of 1.22 +/- 0.44%/min for ER --> Golgi, and 7.68 +/- 1.94%/min for Golgi --> ER transport, revealing a half-time of 113 +/- 70 min for leaving the ER and 1.67 +/- 0.45 min for leaving the Golgi, and accounting for the measured steady-state distribution of VIP36-SP-FP (13% Golgi/87% ER). Perturbing transport with AlF(4)(-) treatment altered VIP36-SP-GFP distribution and changed the rate constants. The parameters of the model suggest that relatively small differences in the first order rate constants, perhaps manifested in subtle differences in the tendency to enter distinct TCs, result in large differences in the steady-state localization of secretory components.


Subject(s)
Carrier Proteins/metabolism , Endoplasmic Reticulum/metabolism , Golgi Apparatus/metabolism , Mannose-Binding Lectins , Membrane Proteins/metabolism , Membrane Transport Proteins , Protein Transport , Secretory Vesicles/metabolism , Animals , Biomarkers , Brefeldin A/pharmacology , COS Cells , Cycloheximide/pharmacology , Humans , Kinetics , Luminescent Proteins/metabolism , Microscopy, Confocal , Microscopy, Video , Protein Synthesis Inhibitors/pharmacology , Protein Transport/drug effects , Recombinant Fusion Proteins/genetics , Recombinant Fusion Proteins/metabolism , Secretory Vesicles/chemistry , Time Factors
12.
Eur Respir J ; 15(5): 844-8, 2000 May.
Article in English | MEDLINE | ID: mdl-10853847

ABSTRACT

Several reports indicate that asthma mortality has increased during the last few decades. International comparisons reveal some striking differences in the pattern of asthma mortality. The authors investigated the asthma mortality rate in the Danish child and youth population 1973-1994 and studied the validity of death certificates. The authors reviewed all death certificates coded as asthma death in the International Classification of Diseases (ICD 8-ICD 10 (1994)) and adjacent respiratory code numbers for the age group 1-19 yrs. Hospital records and autopsy reports were assessed to validate the cause of death. Age-standardized and age-specific mortality rates were calculated. From 1973 to 1987 there was a significant upward trend in the mortality. On subdivision, this trend was limited to the age group 15-19 yrs. Generally the mortality rate decreased from 1988 to 1994. Four per cent coded as asthma were false positive. Twelve per cent were false negative asthma deaths, wrongly coded as due to other causes. Only 62% of all true positive death caused by asthma were appropriately coded. The number of false negative certifications increased with increasing autopsy frequency. Asthma mortality rates in Denmark increased in adolescents during 1973-1987 and decreased from 1988 to 1994. A possible explanation may be an increased awareness of asthma symptoms combined with a steadily improved treatment of asthma. Even in children and young adults under the age of 20 yrs, validity problems still make comparisons between countries difficult; even interpretation of national trends requires caution.


Subject(s)
Asthma/mortality , Death Certificates , Adolescent , Adult , Cause of Death , Child , Child, Preschool , Denmark/epidemiology , Humans , Infant
13.
Pediatr Infect Dis J ; 17(11): 996-1000, 1998 Nov.
Article in English | MEDLINE | ID: mdl-9849981

ABSTRACT

BACKGROUND: Prophylaxis against infection caused by respiratory syncytial virus (RSV) with high titered RSV immunoglobulin or humanized antibody may soon be available in Europe. OBJECTIVE: To study the epidemiology of RSV infections requiring hospitalization in infants <6 months in East Denmark to provide a rational basis for decisions concerning prophylaxis against RSV. METHOD: Populat ion-based retrospective review of case records of infants <6 months admitted to pediatric departments with RSV infection in East Denmark from November 1, 1995, to April 30, 1996. RESULTS: Data were obtained from 459 infants. Seventy-three had predisposing conditions: prematurity, 49; pulmonary disease, 2; congenital heart disease, 7; neurologic disease, 6; others, 9. One preterm infant had bronchopulmonary dysplasia. The incidence of RSV infection requiring hospitalization in East Denmark among infants <6 months was estimated to be 34/1000/season. It was 32/1000/season among term infants and 66/ 1000/season among preterm infants (P<0.001). Infants with predisposing conditions and/or nosocomial infection (n = 24) had significantly more severe courses than otherwise healthy infants (P<0.01). One-hundred thirty infants received respiratory support by nasal continuous positive airway pressure, but only six required mechanical ventilation. No infants died. CONCLUSION: The course of RSV disease in East Denmark was milder than reported elsewhere, possibly as a result of the low prevalence of bronchopulmonary dysplasia in Denmark. However, RSV constitutes a considerable burden to the Danish pediatric health care system, and therefore prophylaxis against RSV is desirable.


Subject(s)
Respiratory Syncytial Virus Infections/epidemiology , Denmark/epidemiology , Female , Hospitalization , Humans , Infant , Infant, Newborn , Male , Respiratory Syncytial Virus Infections/prevention & control , Retrospective Studies , Risk Factors , Statistics, Nonparametric
14.
Article in German | MEDLINE | ID: mdl-9931863

ABSTRACT

Long-term results of femoral angioplasty and stenting are not as successful as open surgical procedures. Transfemoral retrograde recanalisation of the iliac vessel by semiclosed endarterectomy is a low-invasive procedure. Certainly the outcome is characterised by a number of early occlusions caused by dissections or remaining intimal flaps. Recent advances in endovascular management of occlusive disease have changed the situation. Intraoperative control of lumen by angioscopy and removal of occlusive material via TV-monitored endoscopic manipulation has induced better results of endarterectomy. In addition to this more effective recanalisation, the proximal intimal step, mostly at the level of the iliac bifurcation, is managed by intraoperative balloon dilatation and stenting. This combined approach has reduced the necessity of reoperation by about 15%. The cumulative 5-year patency rate for this combined procedure is 88%.


Subject(s)
Angioplasty, Balloon/instrumentation , Arterial Occlusive Diseases/surgery , Endarterectomy/instrumentation , Endoscopes , Ischemia/surgery , Leg/blood supply , Stents , Angioscopes , Combined Modality Therapy , Follow-Up Studies , Humans , Iliac Artery/surgery , Minimally Invasive Surgical Procedures/instrumentation , Reoperation , Treatment Outcome
15.
Ugeskr Laeger ; 159(2): 164-5, 1997 Jan 06.
Article in Danish | MEDLINE | ID: mdl-9012087

ABSTRACT

In a questionnaire study concerning voiding habits among seven year-old children starting school the prevalence of enuresis nocturna was 13.4% among girls and 22.2% among boys. For 5.4% of girls and 8.2% of boys the symptom occurred at least once a week. Half of the children had secondary enuresis. Forty-six percent had consulted their doctor about the problem and 44% had received some kind of treatment. Ten percent had tried an alarm bell and 33% had tried desmopressin.


Subject(s)
Enuresis/psychology , Adult , Attitude of Health Personnel , Attitude to Health , Child , Enuresis/diagnosis , Enuresis/therapy , Female , Humans , Male , Parents/psychology , Surveys and Questionnaires
16.
Acta Paediatr ; 86(12): 1345-9, 1997 Dec.
Article in English | MEDLINE | ID: mdl-9475314

ABSTRACT

In this cross-sectional epidemiological questionnaire survey of 7-8-y-old Danish school entrants with focus on voiding habits, 29% were found to have symptoms that could suggest that bladder control was not fully developed. The frequency of day wetting, urgency, emptying difficulties, nocturnal enuresis, nocturia and encopresis, and the median frequency of voidings are presented. Furthermore, the relationship between urinary tract infections, day wetting, encopresis and voiding habits is investigated. There was an association between previous urinary tract infection in girls and current voiding symptoms, suggesting bladder dysfunction as a predisposing factor to infections. In particular, focus should be placed on girls with squatting on urge and/or emptying difficulties.


Subject(s)
Encopresis/epidemiology , Enuresis/epidemiology , Urinary Retention/epidemiology , Urinary Tract Infections/epidemiology , Urination Disorders/epidemiology , Child , Confidence Intervals , Cross-Sectional Studies , Data Collection , Denmark/epidemiology , Encopresis/diagnosis , Encopresis/physiopathology , Enuresis/diagnosis , Enuresis/physiopathology , Female , Humans , Logistic Models , Male , Prevalence , Risk Factors , Sex Distribution , Surveys and Questionnaires , Urinary Retention/diagnosis , Urinary Retention/physiopathology , Urinary Tract/abnormalities , Urinary Tract Infections/diagnosis , Urinary Tract Infections/physiopathology , Urination Disorders/diagnosis , Urination Disorders/physiopathology
17.
20.
Phys Rev B Condens Matter ; 54(1): 602-605, 1996 Jul 01.
Article in English | MEDLINE | ID: mdl-9984296
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