ABSTRACT
BACKGROUND: This study was performed to explore the total prostate-specific antigen (tPSA) concentration, free PSA (fPSA) concentration, free-to-total PSA ratio (% fPSA), tPSA density (tPSAD), and neutrophil-to-lymphocyte ratio (NLR) in blood in patients with concurrent benign prostatic hyperplasia (BPH) and histologic prostatitis, and to provide new ideas for the diagnosis of prostatitis. METHODS: Patients who underwent transurethral bipolar plasmakinetic prostatectomy from June 2017 to June 2018 were retrospectively divided into two groups according to the degree of pathological inflammation of the resected prostate tissue: group A (BPH with histologic acute and chronic inflammation), group B (BPH with histologic chronic inflammation). The preoperative PSA-related indexes and NLR in blood were respectively compared between two groups. RESULTS: Groups A and B comprised 59 and 41 cases, respectively. The values of tPSA, tPSAD, and NLR were all significantly higher in group A than B, and the value of % fPSA was significantly lower in group A than B (p < 0.05). There was no significant difference for the value of fPSA between the two groups (p > 0.05). CONCLUSIONS: Histologic acute prostatitis can cause changes of PSA-related indexes and NLR in blood, which has important clinical significance in diagnosis of prostatitis.
Subject(s)
Lymphocytes/cytology , Neutrophils/cytology , Prostate-Specific Antigen/blood , Prostatic Hyperplasia , Prostatitis , Aged , Aged, 80 and over , Humans , Leukocyte Count , Male , Middle Aged , Prostate/pathology , Prostatic Hyperplasia/blood , Prostatic Hyperplasia/epidemiology , Prostatic Hyperplasia/pathology , Prostatitis/blood , Prostatitis/epidemiology , Prostatitis/pathology , Retrospective StudiesABSTRACT
BACKGROUND: Physical illness is linked with an increased risk of suicide; however, evidence from China is limited. AIMS: To assess the influence of physical illness on risk of suicide among rural residents of China, and to examine the differences in the characteristics of people completing suicide with physical illness from those without physical illness. METHOD: In all, 200 suicide cases and 200 control subjects, 1:1 pair-matched on sex and age, were included from 25 townships of three randomly selected counties in Shandong Province, China. One informant for each suicide or control subject was interviewed to collect data on the physical health condition and psychological and sociodemographic status. RESULTS: The prevalence of physical illness in suicide cases (63.0%) was significantly higher than that in paired controls (41.0%; χ² = 19.39, p < .001). Compared with suicide cases without physical illness, people who were physically ill and completed suicide were generally older, less educated, had lower family income, and reported a mental disorder less often. Physical illness denoted a significant risk factor for suicide with an associated odds ratio of 3.23 (95% CI: 1.85-5.62) after adjusted for important covariates. The elevated risk of suicide increased progressively with the number of comorbid illnesses. Cancer, stroke, and a group of illnesses comprising dementia, hemiplegia, and encephalatrophy had a particularly strong effect among the commonly reported diagnoses in this study population. CONCLUSION: Physical illness is an important risk factor for suicide in rural residents of China. Efforts for suicide prevention are needed and should be integrated with national strategies of health care in rural China.
Subject(s)
Rural Population/statistics & numerical data , Suicide/statistics & numerical data , Adolescent , Adult , Aged , Aged, 80 and over , Case-Control Studies , Child , China/epidemiology , Female , Humans , Interview, Psychological , Logistic Models , Male , Middle Aged , Risk Factors , Suicide/psychology , Young AdultABSTRACT
The Barratt Impulsiveness Scale-11 (BIS-11) is an important tool for measuring impulsivity in suicide research. This study aimed to assess psychometric characteristics of Chinese version of BIS-11 in suicides and controls of rural China. Data of 200 pairs of suicide cases and living controls were collected by psychological autopsy method. The Cronbach's alpha coefficients of BIS-11 were 0.936 for suicides, and 0.892 for living controls. Convergent validity analysis demonstrated a significantly positive correlation between the scores of BIS-11 with the scores of Beck Hopelessness Scale and Trait Anxiety Inventory. Confirmatory factor analyses indicated that the BIS-11 structure was basically suitable in rural China. With its high reliability, few items in BIS-11 may need a modification in order to further improve the construct validity of this instrument for suicide research in rural China.