ABSTRACT
A total of 24 patients (12 men and 12 women) with squamous cell carcinoma of the eyelid were identified from pathology records at Wills Eye Hospital from 1978 through 1987. Squamous cell carcinoma accounted for 24 of 648 (3.7%) malignant eyelid lesions submitted during the 10-year study period. The median age of patients at the time of diagnosis was 72 years (range, 55 to 96 years). Initial therapy of all tumors involved surgical excision. Four patients developed clinical recurrence of squamous cell carcinoma in a median of 7.5 months after surgery. There were no tumor recurrences when frozen section techniques were applied during the initial surgical excision. The data suggest that the risk of persistence or recurrence of tumor was increased for patients who delayed seeking medical care after the lesion was first noticed and when frozen section control was not used during surgery. None of the patients were known to have developed metastases, and there were no tumor-related deaths.
Subject(s)
Carcinoma, Squamous Cell/pathology , Eyelid Neoplasms/pathology , Aged , Aged, 80 and over , Carcinoma, Squamous Cell/surgery , Cryosurgery , Eyelid Neoplasms/surgery , Eyelids/surgery , Female , Humans , Male , Middle Aged , Neoplasm Recurrence, Local , Prognosis , Risk FactorsABSTRACT
Inadvertent cyclodialysis cleft formation is a rare complication of intraocular surgery. We report a patient in whom a hypotonus cyclodialysis cleft developed following the removal of an anterior chamber intraocular lens. The cleft closed and the hypotony resolved after 1 month of topical atropine therapy.
Subject(s)
Anterior Chamber/surgery , Ciliary Body , Lenses, Intraocular/adverse effects , Ocular Hypotension/etiology , Uveal Diseases/etiology , Aged , Atropine/therapeutic use , Cataract Extraction , Humans , Intraocular Pressure , Male , Ocular Hypotension/therapy , Uveal Diseases/therapy , Visual AcuityABSTRACT
BACKGROUND: Sclera is commonly preserved in glycerin or ethanol before being used for ophthalmic surgery. The purpose of this study was to determine the ability of bacteria to survive in sclera preserved in glycerin or ethanol. METHODS: Fresh sclera was inoculated with Staphylococcus aureus, Streptococcus pneumoniae, or Pseudomonas aeruginosa and transferred to preservative vials containing glycerin, 95% ethanol, or trypticase soy broth (control) and stored at room temperature. Pieces of sclera were removed from preservative at designated intervals over a 14-day period. The sclera was then homogenized, plated on blood agar, and incubated at 37 degrees C. Colonies were counted at 24, 48, and 72 hours. RESULTS: S. pneumoniae, P. aeruginosa, and S. aureus were recovered from glycerin preserved sclera for up to 12 hours, 1.5 days, and 8 days, respectively. No bacteria was recovered from the ethanol preserved sclera. CONCLUSIONS: Bacteria cannot be recovered from ethanol preserved sclera but can survive in glycerin preserved sclera for at least 8 days. Ethanol may offer advantages over glycerin as a scleral preservative due to its greater antibacterial activity.
