ABSTRACT
Leukemias are neoplasms of hematolymphoid cells that predominantly involve the peripheral blood. Cutaneous involvement (leukemia cutis) occurs in chronic myeloid leukemia, chronic lymphocytic leukemia, and in monocytic leukemia. Here, we report a case of a 49-year-old female patient known to have chronic myeloid leukemia presented with multiple cutaneous lesions. The clinicopathologic features were presented and the relevant literature was discussed.
Subject(s)
Granulocyte Precursor Cells/pathology , Leukemia, Myelogenous, Chronic, BCR-ABL Positive/diagnosis , Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology , Leukemic Infiltration , Skin/pathology , Antigens, CD/metabolism , Cell Differentiation , Cell Transformation, Neoplastic , Diagnosis, Differential , Erythema , Female , Granulocyte Precursor Cells/metabolism , Humans , Immunophenotyping , Leukemia, Myelogenous, Chronic, BCR-ABL Positive/physiopathology , Middle Aged , Peroxidase/metabolism , Solitary Pulmonary NoduleABSTRACT
Pleomorphic adenoma, also called benign mixed tumor, is the most common tumor of the salivary glands. About 90% of these tumors occur in the parotid gland and 10% in the minor salivary glands. The most common sites of pleomorphic adenoma of the minor salivary glands are the palates followed by lips and cheeks. Other rare sites include the throat, floor of the mouth, tongue, tonsil, pharynx, retromolar area and nasal cavity. In children, intraoral pleomorphic adenomas of the cheek are extremely rare with only three cases reported to date. Here we report a case of pleomorphic adenoma of minor salivary glands of the cheek in a 17-year-old girl. The mass was removed by wide local excision with adequate margins, and after a follow-up period of three years there were no recurrences. To conclude, pleomorphic adenoma should be considered in the differential diagnosis of cheek masses in youngsters. Wide local excision is to be recommended as the treatment of choice. A close follow-up is necessary postoperatively.
ABSTRACT
A 32-year-old female patient with a history of surgical treatment of cutaneous basal cell carcinomas and recurrent keratocystic odontogenic tumours presented with a painless swelling in the vestibular area of the maxillary premolar region. The lesion was excised, and pathological examination established the diagnosis of ameloblastoma. A review of literature about Gorlin syndrome with ameloblastoma is presented.
