1.
J Pathol
; 163(1): 47-52, 1991 Jan.
Article
in English
| MEDLINE
| ID: mdl-2002423
ABSTRACT
The right testis and epididymis were removed at necropsy from 31 patients who had died with AIDS and examined microscopically. The testes showed interstitial fibrosis in 22 cases, thickening of seminiferous tubule basement membranes in an overlapping 21, and varying degrees of maturation impairment in all. Arrest of spermatogenesis usually occurred at the spermatocyte or spermatid stage. Five epididymides showed an obstructive picture, two with an associated epididymal cytomegalovirus infection. We discuss the possible pathogenesis of the changes in the HIV-infected male genital system and briefly comment on the clinical implications of our findings.
Subject(s)
Acquired Immunodeficiency Syndrome/pathology , Epididymis/pathology , Testis/pathology , Adult , Basement Membrane/pathology , Fibrosis , Humans , Male , Middle Aged , Seminiferous Tubules/pathology , Spermatogenesis
2.
BMJ
; 300(6734): 1239-40, 1990 May 12.
Article
in English
| MEDLINE
| ID: mdl-2354293
Subject(s)
Acquired Immunodeficiency Syndrome/pathology , Synovial Membrane/pathology , Adult , Female , Humans , Knee Joint/pathology , Male , Middle Aged
3.
Lancet
; 1(8441): 1332-3, 1985 Jun 08.
Article
in English
| MEDLINE
| ID: mdl-2860517