ABSTRACT
We report a case of gastric signet cell carcinoma, presenting as cardiac tamponade, in a young male patient. The diagnosis of gastric signet cell carcinoma was confirmed by immunohistochemistry of the lymph node specimen in our patient.
Subject(s)
Carcinoma, Signet Ring Cell/pathology , Cardiac Tamponade/etiology , Pericardial Effusion/etiology , Stomach Neoplasms/pathology , Adult , Humans , Lymphatic Metastasis , Male , Pericardial Effusion/complicationsABSTRACT
The constellation of pseudoxanthoma elasticum, ocular involvement and vascular disturbances is termed Gronblad Strandberg syndrome. Pseudoxanthoma elasticum is a genetic disorder characterized by progressive calcification and fragmentation of elastic fibres in the skin, retina and the cardiovascular system. Typically the cutaneous lesions begin in childhood, but because of their asymptomatic nature they are not noted until adolescence. In some individuals, skin lesions do not develop until later in life. If recognized early, the occurrence of retinal and gastrointestinal hemorrhage and cardiovascular complications can be minimized.
Subject(s)
Basilar Artery/diagnostic imaging , Pseudoxanthoma Elasticum/diagnosis , Vertebrobasilar Insufficiency/diagnosis , Aged , Biopsy , Elastic Tissue/pathology , Humans , Magnetic Resonance Angiography , Male , Pseudoxanthoma Elasticum/complications , Pseudoxanthoma Elasticum/genetics , Radiography , Skin/pathology , Vertebrobasilar Insufficiency/complicationsABSTRACT
Pyrexia of unknown origin has always been a challenging problem to diagnose for physicians. Here we present a case of a splenic tumor, which after histopathology and immunohistochemistry, two possibilities were considered, a diffuse large cell lymphoma--plasmablastic variant and second an anaplastic plasmacytoma. The patient was treated with chemotherapy and on followup he has no evidence of recurrence or any residual lesion.
Subject(s)
Fever of Unknown Origin/diagnosis , Lymphoma, Large B-Cell, Diffuse/diagnosis , Plasmacytoma/diagnosis , Splenic Neoplasms/diagnosis , Fever of Unknown Origin/physiopathology , Humans , Lymphoma, Large B-Cell, Diffuse/physiopathology , Male , Middle Aged , Plasmacytoma/physiopathology , Splenic Neoplasms/physiopathology , Splenic Neoplasms/surgeryABSTRACT
Macrophage Activation Syndrome is a rare and potentially fatal disease, to be considered in patients with a SIRS like clinical presentation. Falling ESR and hyperferritinemia in the appropriate clinical setting can be the greatest clues. We report a case in which a female admitted with fever and rash, initially had systemic inflammatory response syndrome (SIRS) like clinical presentation, but eventually proved to be a rare case of fatal Macrophage Activation Syndrome.
