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Toxins (Basel) ; 6(3): 1021-35, 2014 Mar 06.
Article in English | MEDLINE | ID: mdl-24662524

ABSTRACT

Limnothrix (strain AC0243) is a cyanobacterium, which has only recently been identified as toxin producing. Under laboratory conditions, Bufo marinus larvae were exposed to 100,000 cells mL(-1) of Limnothrix (strain AC0243) live cultures for seven days. Histological examinations were conducted post mortem and revealed damage to the notochord, eyes, brain, liver, kidney, pancreas, gastrointestinal tract, and heart. The histopathological results highlight the toxicological impact of this strain, particularly during developmental stages. Toxicological similarities to ß-N-Methylamino-L-alanine are discussed.


Subject(s)
Bacterial Toxins/toxicity , Bufo marinus/growth & development , Cyanobacteria , Animals , Brain/drug effects , Brain/growth & development , Brain/pathology , Eye/drug effects , Eye/growth & development , Eye/pathology , Gastrointestinal Tract/drug effects , Gastrointestinal Tract/growth & development , Gastrointestinal Tract/pathology , Heart/drug effects , Heart/growth & development , Kidney/drug effects , Kidney/growth & development , Kidney/pathology , Larva/drug effects , Larva/growth & development , Liver/drug effects , Liver/growth & development , Liver/pathology , Myocardium/pathology , Notochord/drug effects , Notochord/growth & development , Notochord/pathology , Pancreas/drug effects , Pancreas/growth & development , Pancreas/pathology
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