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Muscle Nerve ; 23(1): 44-57, 2000 Jan.
Article in English | MEDLINE | ID: mdl-10590405

ABSTRACT

Patients with laryngeal motor control disorders need improved dynamic glottal closure for speech and swallowing. To evaluate the functional outcome of intermittent chronic thyroarytenoid muscle stimulation in an animal model, 6 canines were implanted with bilateral Medtronic Xtrel systems containing Peterson-type electrodes in the inferior and superior portions of the thyroarytenoid muscle. Stimulation was on one side only at 60 Hz, for 5 s on and 5 s off, over 8 h, 5 days per week, up to 8 months. Monthly videorecordings were done under anesthesia to measure the voltage threshold for detectable movement on each side, and vocal fold displacement and velocity during maximal stimulation of each side. Movement thresholds were lower in the inferior portion of the thyroarytenoid muscle (P

Subject(s)
Glottis/physiology , Laryngeal Muscles/physiology , Animals , Biomechanical Phenomena , Dogs , Electric Stimulation , Electrodes, Implanted , Electrophoresis, Polyacrylamide Gel , Female , Functional Laterality/physiology , Glottis/diagnostic imaging , Glottis/metabolism , Laryngeal Muscles/diagnostic imaging , Laryngeal Muscles/metabolism , Male , Myosin Heavy Chains/metabolism , Telemetry , Time Factors , Tomography, X-Ray Computed , Vocal Cords/physiology
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