ABSTRACT
A case of cerebral cryptococcosis is described. Cryptococcus neoformans is the most pathogenic in humans. It often affects lungs, skin, muscles and tissues of the Central Nervous System (CNS). In case of CNS involvement, the main clinically diagnosed form of the disease is cryptococcal meningitis. The authors describe a patient with non-specific symptoms of anxiety-depressive disorder and further development of neurological symptoms and behavioral deviations.
Subject(s)
Cryptococcosis , Cryptococcus neoformans , Depressive Disorder , Meningitis, Cryptococcal , Central Nervous System , HumansABSTRACT
OBJECTIVE: To compare clinical features of eating disorders and parameters of monoamine metabolism. MATERIAL AND METHODS: Authors examined 21 patients with eating disorders during 2008-2011 using clinical/psychopathological method. To evaluate the status of monoamine neuromediator system, urine levels of dopamine, noradrenalin and adrenaline excretion were measured using high-yield liquid chromatography with electrochemical detection. The reference group included 26 sex- and age-matched volunteers. RESULTS AND CONCLUSION: The common patterns of the pathogenesis of compulsive urges of different origin were identified. The results indicate not only nonspecific changes in catecholamine systems of patients with eating disorders associated with different stress disorders but also demonstrate the pathogenetic correlations between dopaminergic activity and clinical symptoms of addiction.
Subject(s)
Catecholamines/urine , Feeding and Eating Disorders/urine , Dopamine/urine , Epinephrine/urine , Feeding Behavior , Female , Humans , Male , Norepinephrine/urine , UrinalysisABSTRACT
Sixty five patients, aged 48-87, with prostate cancer at different stages were studied. Borderline mental disorders were found in all the patients. In the majority of them, affective disorders in the form of anxiety-depressive (52.3%) and astheno-depressive (24.6%) syndromes were observed. Astheno-hypochondriacal and dysphoric syndromes were detected less frequently (in 15.4% and 7.7% of the cases, respectively).
