[Use of the PFK-01 psychophysiologic unit in the diagnosis of alcoholic patients]. / Ispol'zovanie kompleksa priborov PFK-01 v diagnostike bol'nykh alkogolizmom.

Alcoholic patients were tested on production of short time intervals by means of psychophysiological computer-controlled unit PFK-01 after the dedicated software was completed. Subjective time rate was related to the emotional state of patients. A tendency towards hypoproduction, i.e. towards acceleration of subjective time rate, was associated with the state of anxiety.

[Effect of fenibut on the nocturnal sleep of patients with the alcoholic abstinence syndrome]. / Vliianie fenibuta na nochnoi son bol'nykh s alkogol'nym abstinentnym sindromom.

The authors studied the effect of the tranquilizer phenibut on sleep disturbances in alcoholics at the initial period following alcohol withdrawal. Sleep was registered polygraphically during 2 nights in 12 patients taking the drug and in 10 control patients. The drug did not affect the latent period of falling asleep, increasing, however, the duration of two major phases of sleep and reducing the duration of the drowsiness stage. There was no marked influence on the subjective assessment of sleep.

[Effect of phenazepam on the nocturnal sleep of patients with the alcoholic abstinence syndrome]. / Vliianie fenazepama na nochnoi son bol'nykh s alkogol'nym abstinentnym sindromom.

The authors studied the effect of phenazepam, a benzodiazepine derivative, on sleep disorders in alcoholic patients at the first period following alcohol intake discontinuation. Polygraphic registration of the sleep pattern was performed for two nights in 18 patients, receiving the drug and in ten patients of the control group. The drug use was associated with the following events: the latent period of falling asleep diminished, the total duration of sleep increased, the duration of consciousness "inside the sleep" decreased. As a result of the second stage recovery, the duration of the phase of slow sleep enhanced with no evidence of delta-sleep recovery. The duration of the fast sleep phase increased. The patients showed a marked improvement of sleep quality.

[Night sleep in patients with the alcohol abstinence syndrome against a background of detoxification therapy]. / Nochnoi son bol'nykh s alkogol'nym abstinentnym sindromom na fone dezintoksikatsionnoi terapii.

Polygraphic records of night sleep taken in 10 alcoholics for three days after the cessation of the alcohol intake showed the following disorders: a disturbance of the sleep cyclic organization, a sleep fragmentation, a considerable prolongation of the drowsiness (stage I), a sharp reduction of the delta-sleep stages. One to two weeks after the abstinence onset stage I was still too long, and the delta-sleep stage remained shorter than normal, despite a clinical improvement and cessation of complaints.

[Sujective evaluation of the duration of sleep periods: role of actual time and the representation rate of different EEG stages]. / Sub"ektivnaia otsenka dlitel'nosti periodov sna: znachenie real'nogo vremeni i predstavlennosti raznykh EEG-stadii.

Subjective estimations of the duration of night sleep periods and their actual duration were compared in 29 healthy men 21--36 years of age, awoken from the night sleep. The comparisons concerned the duration of consecutive sleep cycles, long (almost whole sleep cycles) and short ("parts of the cycles") periods, short periods ("parts of the cycle") without REM and with it. It has been found that long and short sleep periods are correspondingly reflected in the subjective estimation of their duration. The comparison of the estimation rates of various stages revealed that the highest subjective estimation, reduced to an hour of real time (subjective "hour estimation") in the first three sleep cycles characterises the cycle parts, including REM, whereas the lowest one--cycle parts, represented only by slow sleep stages, including delta-sleep. Subjective estimation of the sleep cycle duration regularly lowers throughout night sleep from evening till morning. Thus, subjective estimation of the duration of sleep periods is determined by two factors: their actual duration and manifestation rate of different sleep stages. The course of subjective time count in the sleep cycle seems to be uneven: it is slowed down in delta-sleep and accelerated in REM sleep following delta-sleep.