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Ross Fiziol Zh Im I M Sechenova ; 90(8): 1026-32, 2004 Aug.
Article in Russian | MEDLINE | ID: mdl-15552368

ABSTRACT

Donor splenocytes and timocytes have an ability to stimulate erythropoesis after massive blood-letting. Changing of functional state of the immune system by means of immune modulators action affects the character and expressiveness of hemopoiesis regulation function of lymphocytes. Splinocytes and thymocytes depress granulocytopoiesis in the recipients' bone marrow after activation by T- and B-lymphocytes. The activation of B-lymphocytes determines the cells' capacity to increase concentration of thrombocytes in the blood. Donor thymocytes can activate erythropoiesis and granulocytopoiesis after macrophages stimulation.


Subject(s)
Hematopoiesis/physiology , Lymphocyte Activation/immunology , Lymphocytes/immunology , Adjuvants, Immunologic/pharmacology , Animals , Bone Marrow Cells/immunology , Erythrocyte Count , Hemorrhage/immunology , Lymphocyte Activation/drug effects , Lymphocytes/drug effects , Macrophages/drug effects , Macrophages/immunology , Male , Organic Chemicals , Rats , Rats, Inbred Strains , Spleen/cytology , Spleen/immunology , Thymus Gland/cytology , Thymus Gland/immunology , Thymus Hormones/pharmacology
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