1.
Pediatr Infect Dis J
; 40(12): e527-e528, 2021 12 01.
Article
in English
| MEDLINE
| ID: mdl-34591798
2.
First Report of SARS-CoV-2 Detection in Cerebrospinal Fluid in a Child With Guillain-Barré Syndrome.
Pediatr Infect Dis J
; 40(7): e274-e276, 2021 07 01.
Article
in English
| MEDLINE
| ID: mdl-33990525
ABSTRACT
Underlying mechanisms on the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and neurologic complications are still poorly understood. Cases of Guillain-Barré Syndrome (GBS) have been linked to the SARS-CoV-2 infection as the result of dysregulated immune response with damage in neuronal tissues. In the current report, we present the first pediatric case of GBS with detection of SARS-CoV-2 in the cerebrospinal fluid (CFS). This unique case of COVID-19-associated GBS with detection of SARS-CoV-2 RNA in the CSF indicates direct viral involvement inducing peripheral nerve inflammation.