ABSTRACT
Oral squamous cell carcinoma (OSCC) is a world health problem with approximately 50% of patients having a 5-year survival rate. A change in the demographics of the disease is now being recognised, particularly in Europe, where it is increasingly being seen in young males. While a variety of risk factors are important in OSCC, it is tobacco that plays a central part in the pathogenesis of the disease. Narghile is an old form of tobacco use but in the past decade, there has been a resurgence in this form of smoking. The practice is particularly common in young males and females from the Middle East but with the advent of immigration and globalisation, its use is becoming more widespread. It is now not uncommon to see narghile smoking in western countries such as the UK and USA. Studies describing the oral effects of narghile are unfortunately scarce. While adverse effects such as periodontal bone loss and dry socket have been described, its association with OSCC cannot be excluded. Variation in the type of narghile, the type of tobacco and the presence of co-factors such as cigarette smoking may all influence clinical outcome. In the present study, the practice of narghile smoking is reviewed in terms of its effect on health, particularly oral health. The association of narghile smoking and adverse effects on the orofacial region will be outlined, namely, periodontal disease, potentially malignant lesions and oral cancer.
Subject(s)
Smoking/adverse effects , Carcinoma, Squamous Cell/etiology , Female , Global Health , Humans , Male , Mouth Neoplasms/etiology , Periodontal Diseases/etiology , Smoking/ethnology , Nicotiana/adverse effectsABSTRACT
The prevalence of Candida species with and without denture-related stomatitis were evaluated in 167 Jordanian patients. The study revealed that 47 (28%) of the patients with denture-related stomatitis were colonized with Candida species (clinical group). Candida albicans was responsible for most cases of denture-related stomatitis (72%), and it was the only species capable of secreting aspartic proteinases. The study also indicated that candidal colonization was not influenced by predisposing haematological deficiencies, as both the clinical and control patient groups showed comparable haematological parameters and the differences were not significant (P > 0.05). All Candida species isolates were 100% susceptible to amphotericin B, while these isolates were less susceptible (25-75%) to fluconazole.
Subject(s)
Candida/isolation & purification , Candidiasis, Oral/etiology , Stomatitis, Denture/complications , Aged , Amphotericin B/pharmacology , Antifungal Agents/pharmacology , Aspartic Acid Endopeptidases/metabolism , Candida/drug effects , Candida/metabolism , Candidiasis, Oral/blood , Candidiasis, Oral/epidemiology , Female , Fluconazole/pharmacology , Humans , Jordan/epidemiology , Male , Middle Aged , Prevalence , Stomatitis, Denture/epidemiologyABSTRACT
The aim of this study was to compare some of the physical properties of a heat-cured, a self-cured and a visible light-cured acrylic resin, and to evaluate the suitability of visible light-cured resin as a repair material for dentures made of heat-cured acrylic resin. Transverse strength, surface hardness and impact strength were determined for the three materials and the efficiencies of light-cured and self-cured resins, when used as a repair material, were evaluated by testing the transverse strength of repaired heat-cured specimens 1 hour, 1 week and 1 month after repair. The results showed that the rigidity of specimens repaired with light-cured resin improved with longer water storage. However, their transverse strength reached a maximum after one day and was reduced after 1 month. The rigidity and transverse strength of specimens repaired with self-cured resin were not influenced significantly by water storage and the transverse strength was significantly higher than the light-cured repaired specimens.
