ABSTRACT
To examine the effect of fish oil supplementation on the fatty acid (FA) composition of human milk and maternal and infant erythrocytes, five lactating women were supplemented with 6 g of fish oil daily for 21 d. Usual maternal diets contained 1,147 mg of total n-3 FA, with 120 mg from very long-chain (> C18) n-3 FA. Supplementation increased dietary levels to 3,092 mg of total n-3 FA and 2,006 mg of very long-chain n-3 FA. Milk samples were collected daily, prior to fish oil ingestion, and at 4-h intervals on days 1, 7, 14 and 21. Milk n-3 FA content increased within 8 h and reached steady state levels within one week. The n-6 fatty acid content decreased. Erythrocyte eicosapentaenoic acid content increased from 0.24% to 1.4% (P < 0.01) in mothers and from 0.11% to 0.70% (P < 0.05) in infants. Docosapentaenoic acid increased from 1.4% to 2.2% (P < 0.05) in mothers and from 0.30% to 0.78% (P < 0.01) in infants. There was no significant change in docosahexaenoic acid or n-6 fatty acid content. Maternal platelet aggregation responses were variable. No differences in milk or plasma tocopherol levels were noted.
Subject(s)
Dietary Fats, Unsaturated/pharmacology , Erythrocytes/metabolism , Fatty Acids/blood , Fatty Acids/metabolism , Fish Oils/pharmacology , Milk, Human/metabolism , Eicosapentaenoic Acid/blood , Fatty Acids, Unsaturated/blood , Fatty Acids, Unsaturated/metabolism , Female , Humans , Infant, Newborn , Lactation/physiology , Platelet AggregationABSTRACT
Physicians must be prepared to provide comprehensive pretravel advice to their patients. Because world conditions are constantly changing, it is necessary to obtain accurate and current information. Common health problems that may be faced by any traveler include accidents, motion sickness, and jet lag. Physicians must familiarize themselves with the many forms of insurance available for the traveler.
Subject(s)
Travel , Humans , Immunization , Patient Education as TopicSubject(s)
Computers , Immunization , Preventive Medicine/methods , Software , Travel , Family Practice , Global Health , Humans , Patient Education as TopicABSTRACT
A false-positive test for occult blood may result when stool samples are collected from a toilet bowl contaminated with urine that contains blood. This was the case in three patients subjected to extensive work-up for gastrointestinal bleeding. In vitro tests confirmed this reaction. Hematuria may not be noted by the patient, or it may be masked by colored toilet bowl cleaners when samples for test cards are collected at home.
Subject(s)
Hematuria , Occult Blood , False Positive Reactions , HumansABSTRACT
A 61 year-old male patient developed gynecomastia after starting theophylline. The gynecomastia regressed when the theophylline was discontinued. No other endogenous or exogenous cause for the gynecomastia could be found except for the theophylline.
