1.
J Med Virol
; 80(3): 430-3, 2008 Mar.
Article
in English
| MEDLINE
| ID: mdl-18205212
ABSTRACT
This study reports the first isolation and partial genetic characterization of Chikungunya virus (CHIKV) from patients during a 2006-2007 dengue-like syndrome outbreak in Gabon. The isolated viruses were phylogenetically close to strains isolated in the Democratic Republic of the Congo 7 years ago and to strains isolated more recently in Cameroon. These results indicate a continuing circulation of a genetically stable CHIKV population during 7 years in Central Africa.
Subject(s)
Alphavirus Infections/epidemiology , Alphavirus Infections/virology , Chikungunya virus/isolation & purification , Adolescent , Adult , Alphavirus Infections/diagnosis , Chikungunya virus/classification , Chikungunya virus/genetics , Child , Disease Outbreaks , Female , Gabon/epidemiology , Humans , Male , Middle Aged , Phylogeny
2.
Antimicrob Agents Chemother
; 46(1): 225-8, 2002 Jan.
Article
in English
| MEDLINE
| ID: mdl-11751139
ABSTRACT
FR160, a catechol iron chelator, and tetracyclines or norfloxacin exert in vitro additive or synergistic activity against a chloroquine-resistant Plasmodium falciparum clone. FR160 shows antagonistic effects in association with macrolides, ofloxacin, and rifampin.
