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1.
Radiologe ; 41(12): 1056-62, 2001 Dec.
Article in German | MEDLINE | ID: mdl-11793930

ABSTRACT

The term juxta-facet cyst summarizes synovial cysts, arising from degenerated facet joints and ganglion cysts, developing from mucinous degeneration of periarticular connective tissue. Most juxta-facet cysts are observed at the L4/5 level, which generally has the most motion within the lumbar spine. In this retrospective study 31 juxta-facet cysts in 28 patients were detected within 2898 lumbar MRI studies over a 2-year period (frequency 1%). 24 patients complained of back and lower extremity pain, the other 4 patients had unilateral back pain. In 7 cases radicular symptoms were observed, in 6 patients a neurogenic claudication. In 78% of the patients juxta-facet cysts were responsible for clinical symptoms. MRI is the diagnostic imaging technique of choice due to a high sensitivity. The juxta-facet cysts were located extradural, laterally to the thecal sack and adjacent to a degenerated facet joint. In all but one cases the cysts showed a signal intensity equivalent to cerebrospinal fluid. T2-weighted pulse sequences in sagittal orientation were very useful in delineating the hypointense cyst wall. In 1 patient with acute radicular pain MRI demonstrated a subacute hemorrhage within a juxta-facet cyst. Calcifications and gas-filled cysts can be missed with MRI, but will be demonstrated by computed tomography. 45% of the juxta-facet cysts showed an enhancement of the cyst wall after injection of Gd-DTPA. Spontaneous reduction or resolution of the cyst may occur during rest. Injection of corticosteroids into the corresponding facet joint may reduce the inflammatory process and resolve the symptoms in up to 70%. Surgical resection of the cyst is indicated in case of intractable pain and significant neurologic deficit and generally produces good relief from radicular symptoms.


Subject(s)
Central Nervous System Cysts/diagnosis , Image Enhancement , Lumbar Vertebrae/pathology , Magnetic Resonance Imaging , Spinal Diseases/diagnosis , Synovial Cyst/diagnosis , Aged , Aged, 80 and over , Diagnosis, Differential , Female , Humans , Low Back Pain/etiology , Male , Middle Aged , Radiculopathy/etiology , Retrospective Studies , Sensitivity and Specificity
2.
J Nucl Med ; 38(5): 802-8, 1997 May.
Article in English | MEDLINE | ID: mdl-9170450

ABSTRACT

UNLABELLED: The high glucose utilization of normal gray matter limits the detection of brain tumor tissue by PET using 18F-fluorodeoxyglucose (FDG). The aim of this study was to evaluate whether the examination of amino acid transport with the SPECT tracer 123l-alpha-methyl-L-tyrosine (IMT) allows better identification of tumor tissue than FDG-PET. METHODS: Nineteen patients (16 with gliomas, 3 with nontumorous lesions) were included in the study. Two independent observers classified PET and SPECT images as positive or negative for tumor tissue and defined the extent of tumor with regions of interest. Tracer uptake of FDG and IMT was quantified by calculating the tumor uptake relative to contralateral gray and white matter. RESULTS: SPECT studies were interpreted concordantly in 18 patients (kappa = 0.77) and all tumors were identified by both observers. PET studies were interpreted discordantly in 4 patients (kappa = 0.52) and only 10 tumors were identified by both observers, interobserver variability in definition of tumor extent was significantly lower in the IMT-SPECT than in the FDG-PET studies (p = 0.03). Mean tumor uptake relative to gray and white matter was 1.93 +/- 0.42 and 2.25 +/- 0.46 for IMT and 0.93 +/- 0.32 and 1.61 +/- 0.52 for FDG. All tumor uptake ratios were significantly (p < 0.01) higher for IMT than FDG, even when only glioblastomas were analyzed. No significant correlation was observed between the various uptake ratios of FDG and IMT. CONCLUSION: Despite the lower resolution and lower sensitivity of SPECT compared with PET, IMT-SPECT was clearly superior to FDG-PET in the detection and delineation of tumor tissue.


Subject(s)
Astrocytoma/diagnostic imaging , Brain Neoplasms/diagnostic imaging , Brain/diagnostic imaging , Deoxyglucose/analogs & derivatives , Fluorine Radioisotopes , Glioblastoma/diagnostic imaging , Iodine Radioisotopes , Methyltyrosines , Tomography, Emission-Computed, Single-Photon , Tomography, Emission-Computed , Brain/metabolism , Evaluation Studies as Topic , Female , Fluorodeoxyglucose F18 , Humans , Male , Middle Aged , Neoplasm Recurrence, Local/diagnostic imaging , Sensitivity and Specificity
3.
Z Gastroenterol ; 34(10): 704-7, 1996 Oct.
Article in German | MEDLINE | ID: mdl-9012224

ABSTRACT

In patients with Crohn's disease arthritis of the large joints, osteomalacia, osteoporosis and aseptic bone necrosis as a consequence of malabsorption and glucocorticoid intake may occur. The case of a patient with long-standing Crohn's disease is presented who subsequently developed abacterial osteomyelitis of the jaw ("osteomyelitis sicca"). The symptoms of the osteomyelitis improved under immuno-suppressive therapy. Because the etiopathogenetic concepts for Crohn's disease and osteomyelitis sicca are similar, the latter could be a rare extraintestinal manifestation in Crohn's disease, not described previously.


Subject(s)
Crohn Disease/diagnosis , Mandibular Diseases/diagnosis , Osteomyelitis/diagnosis , Adult , Combined Modality Therapy , Crohn Disease/drug therapy , Debridement , Diagnostic Imaging , Drug Therapy, Combination , Humans , Immunosuppressive Agents/administration & dosage , Male , Mandibular Diseases/drug therapy , Mercaptopurine/administration & dosage , Methylprednisolone/administration & dosage , Osteomyelitis/drug therapy
7.
Rofo ; 158(6): 577-82, 1993 Jun.
Article in German | MEDLINE | ID: mdl-8507850

ABSTRACT

During a period of 18 months about 70 patients suffering from an unstable spinal injury were operated in the surgical department of our clinic. In 50 of these patients it was possible to correlate the results of preoperative radiography and CT with the operative findings. Several cases of distraction instability in the dorsal column had not been recognised in the preoperative radiologic evaluation. Therefore the rationale of this study was the question as to whether modern CT technology can help to avoid such wrong diagnoses. For that purpose radiographs, axial CT-scans of 2 mm thickness or less, sagittal and coronal 2D and (in 35 cases) 3D reconstructions were re-evaluated step by step by a specifically trained radiologist without knowing the operative findings. 15 additional lesions out of 28 were demonstrated and specifically classified as distraction instabilities of the dorsal column using the improved CT technology.


Subject(s)
Image Processing, Computer-Assisted , Joint Instability/diagnostic imaging , Spinal Injuries/diagnostic imaging , Tomography, X-Ray Computed/methods , Adult , Female , Humans , Joint Instability/epidemiology , Male , Middle Aged , Retrospective Studies , Spinal Injuries/epidemiology
8.
Rofo ; 158(5): 416-22, 1993 May.
Article in German | MEDLINE | ID: mdl-8490149

ABSTRACT

The MRT scans of 57 patients with Ewing or osteosarcomas and 34 patients with haematogenous osteomyelitis or periostitis/stress fractures were examined in order to determine whether a distinction between benign or malignant lesions is possible. Four criteria were evaluated: the margin of the bone marrow component; intensity and homogeneity of the T1 weighted signal in the bone marrow; presence of an extraosseous structured soft tissue mass and/or soft tissue edema. It was found that central osteosarcomas and Ewing's sarcomas reduced signal intensity of the marrow to become muscle-isointense with a well-defined margin. In acute haematogenous osteomyelitis and periostitis/stress fracture the marrow lesion was not sharply demarcated. In contrast to patients with bone sarcomas, only one case of osteomyelitis showed an extraosseous structured soft tissue mass. On the basis of these findings we believe that acute haematogenous osteomyelitis can be distinguished with high degree of accuracy from Ewing's sarcoma and central osteosarcomas.


Subject(s)
Bone Diseases/diagnosis , Bone Neoplasms/diagnosis , Magnetic Resonance Imaging , Sarcoma/diagnosis , Adolescent , Adult , Bone and Bones/pathology , Child , Diagnosis, Differential , Female , Fractures, Stress/diagnosis , Humans , Leg , Male , Osteomyelitis/diagnosis , Osteosarcoma/diagnosis , Periostitis/diagnosis , Sarcoma, Ewing/diagnosis
10.
Rofo ; 156(4): 369-73, 1992 Apr.
Article in German | MEDLINE | ID: mdl-1571520

ABSTRACT

The differentiation between a "pseudo" pneumoperitoneum and a pneumoperitoneum due to a perforation may be difficult in unconscious or ventilated patients. The use of CT for differentiating between extraperitoneal and intraperitoneal air is demonstrated by three examples in whom air below the diaphragm was shown by conventional radiographs. CT can prove the extraperitoneal position of an air crescent below the diaphragm in cases of "pseudo" pneumoperitoneum. CT will also show that extraperitoneal air does not rise in the way that true peritoneal air will do when the patient is supine. In this position the viscera therefore do not fall backwards in the presence of a "pseudo" pneumoperitoneum.


Subject(s)
Pneumoperitoneum/diagnostic imaging , Respiration , Tomography, X-Ray Computed , Adult , Child , Diagnosis, Differential , Female , Humans , Male , Mediastinal Emphysema/diagnostic imaging , Middle Aged , Pneumoperitoneum/etiology , Pneumothorax/diagnostic imaging , Posture
13.
Rofo ; 155(5): 428-31, 1991 Nov.
Article in German | MEDLINE | ID: mdl-1954361

ABSTRACT

In order to prevent aspiration following loss of function of the UOS a new sphincter may develop. This usually arises from the oblique part of the cricopharyngeus muscle and the caudal part of the thyropharyngeus muscle and it is functionally independent of the UOS. We examined 40 patients by cinematography: these included 30 patients with a Zenker's diverticulum, 8 patients following myotomy of the UOS and 2 patients with tumour infiltration of the UOS. The new sphincter could be demonstrated in 70% of patients with Zenker's diverticulum: its function depended on the size and localisation of the diverticulum. Following myotomy of the UOS the new sphincter is usually only just perceptible. In one case there was, however, marked dyskinesia, requiring further myotomy.


Subject(s)
Cerebrovascular Disorders/physiopathology , Esophagogastric Junction/physiopathology , Zenker Diverticulum/physiopathology , Adult , Aged , Aged, 80 and over , Cerebrovascular Disorders/epidemiology , Cineradiography , Esophagogastric Junction/abnormalities , Esophagogastric Junction/surgery , Female , Humans , Male , Middle Aged , Retrospective Studies , Zenker Diverticulum/epidemiology
16.
Rofo ; 154(4): 383-7, 1991 Apr.
Article in German | MEDLINE | ID: mdl-1850153

ABSTRACT

Two impressions can be seen on the ventral aspect of the hypopharynx and upper oesophagus; on static images it is difficult to differentiate these from small tumours. In order to evaluate this region more accurately, we have examined 150 patients by means of rapid rate cinematography. In 52.6% we found a constant irregular or convex impression formed by the cricoid; in the other cases this was not seen or was quite minimal. In 93% a sub-cricoid impression could be demonstrated which was due to lax mucosa. Characteristically, this showed a variable appearance during the passage of a bolus. Only the cricoid impression was associated with dysphagia.


Subject(s)
Hypopharynx/diagnostic imaging , Adult , Aged , Barium Sulfate , Cineradiography , Deglutition , Deglutition Disorders/diagnostic imaging , Diagnosis, Differential , Female , Humans , Male , Middle Aged
19.
Rofo ; 152(5): 583-6, 1990 May.
Article in German | MEDLINE | ID: mdl-2160694

ABSTRACT

The diagnosis of epiphyseolysis of the femoral head in its early stages is often unclear when using conventional radiography. In order to obtain additional information, we examined seven patients by means of MRT. In all cases the T1-weighted sequences showed widened, ill-defined epiphyseal plates. The epiphyseal displacement was shown accurately by sections of the sagittal plane. T2-weighted sequences showed the presence of an effusion in the hip joints of five patients. In all patients there was increased signal intensity in the metaphysis and in the femoral neck and head. The increased signal intensity appears to be an early sign for the presence of an epiphyseolysis.


Subject(s)
Epiphyses, Slipped/diagnosis , Femur Head/pathology , Magnetic Resonance Imaging , Adolescent , Female , Humans , Male
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