Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 16 de 16
Filter
Add more filters










Publication year range
1.
J Indian Med Assoc ; 96(11): 338-40, 1998 Nov.
Article in English | MEDLINE | ID: mdl-10218320

ABSTRACT

Ten patients of chronic obstructive pulmonary disease were studied for changes in ultrastructure of the glomeruli, serum immunoglobulin and complement levels. The glomeruli showed proliferation in the mesangium in 90% patients and electron dense deposits in the mesangium in 30% patients. IgA and IgG were usually elevated whereas complements were usually depressed in most of these patients. It is suggested that repeated respiratory infections in these subjects may be responsible for mesangioproliferative type of glomerulonephritis, high IgA and IgG levels. The complements are activated and they take part in immune complex formation getting deposited in mesangium.


Subject(s)
Glomerulonephritis, Membranoproliferative/pathology , Kidney Glomerulus/ultrastructure , Lung Diseases, Obstructive/complications , Adult , Biopsy, Needle , Complement C3/analysis , Complement C4/analysis , Glomerulonephritis, Membranoproliferative/etiology , Humans , Immunoglobulin A/analysis , Immunoglobulin G/analysis , Immunohistochemistry , Kidney Glomerulus/immunology , Lung Diseases, Obstructive/pathology , Male , Middle Aged , Reference Values
2.
J Assoc Physicians India ; 43(1): 15-6, 1995 Jan.
Article in English | MEDLINE | ID: mdl-9282630

ABSTRACT

Electrocardiograms of 984 healthy subjects residing in village Kalpa at the height of 9000 feet above sea level were studied. Right ventricular hypertrophy (RVH) was observed in 9 (0.914%) subjects. Electrocardiographic evidence of ischaemic heart disease was found in 6 (0.609%) subjects.


Subject(s)
Electrocardiography , Hypertrophy, Right Ventricular/epidemiology , Myocardial Ischemia/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , Altitude , Atrial Fibrillation/epidemiology , Female , Heart Block/epidemiology , Heart Rate , Humans , Hypertension/epidemiology , Hypertrophy, Left Ventricular/epidemiology , India/epidemiology , Male , Middle Aged , Myocardial Infarction/epidemiology , Prevalence , Pulmonary Heart Disease/epidemiology
4.
J Indian Med Assoc ; 92(3): 80-1, 1994 Mar.
Article in English | MEDLINE | ID: mdl-8057004

ABSTRACT

A herbal powder containing guar gum, methi, tundika and meshasringi was administered to 30 control and 30 type 2 (non-insulin dependent) diabetes mellitus patients for a month. Total serum cholesterol and its fractions eg, high density lipoprotein, low density lipoproteins, very low density lipoproteins and serum triglyceride were determined before and after the trial period. Total and low density lipoprotein (LDL) cholesterols were reduced significantly after the therapy. There were no significant changes in high density lipoproteins (HDL), very low density lipoproteins (VLDL) or triglyceride levels. Side-effects eg, mild flatulence and looseness of bowel were noticed in less than 40% cases.


Subject(s)
Cholesterol, HDL/blood , Cholesterol, LDL/blood , Cholesterol, VLDL/blood , Cholesterol/blood , Diabetes Mellitus, Type 2/blood , Dietary Fiber , Food, Fortified , Galactans/administration & dosage , Magnoliopsida , Mannans/administration & dosage , Triglycerides/blood , Adult , Diabetes Mellitus, Type 2/diet therapy , Female , Humans , Male , Middle Aged , Plant Gums , Powders , Time Factors
5.
J Assoc Physicians India ; 42(1): 33-5, 1994 Jan.
Article in English | MEDLINE | ID: mdl-7836245

ABSTRACT

A herbal powder consisting of Guargum, Methi, Tundika and Meshasringi was administered to thirty control and thirty NIDDM patients twice daily before principal meals for four weeks. Oral GTT showed improvement in both control and patient groups. Serum total and LDL cholesterol also fell significantly in both the groups after the trial period. Test meal of the herbal powder with D-Xylose excretion was otherwise normal. Follow up for upto two years did not reveal any long term side effect of the powder. This powder, therefore, can be effectively used to reduce postprandial blood glucose and LDL cholesterol in NIDDM patients as a long term measure.


Subject(s)
Galactans/therapeutic use , Hyperglycemia/prevention & control , Hyperlipidemias/prevention & control , Plant Extracts/therapeutic use , Plants, Medicinal , Absorption , Blood Glucose/analysis , Case-Control Studies , Cholesterol/blood , Cholesterol, LDL/blood , Diabetes Mellitus, Type 2/blood , Diabetes Mellitus, Type 2/prevention & control , Diabetes Mellitus, Type 2/urine , Drug Combinations , Female , Follow-Up Studies , Glucose Tolerance Test , Humans , Hyperglycemia/blood , Hyperlipidemias/blood , Male , Mannans/therapeutic use , Middle Aged , Plant Gums , Trigonella , Xylose/pharmacokinetics , Xylose/urine
6.
J Assoc Physicians India ; 39(9): 692-3, 1991 Sep.
Article in English | MEDLINE | ID: mdl-1726099

ABSTRACT

Electrocardiographic (ECG) changes were studied in 120 consecutive subjects during and after upper GI endoscopy done in ambient hypoxia (PO2-120 mmHg) at Shimla (2200 m). No premedication was given to any of the subjects. There were 75 men and 44 women. Fifty three subjects were aged 40 years or below (Group I) and 67 subjects were above 40 (Group II). There were 29 subjects with and 91 subjects without cardiac diseases. Increase in heart rate was seen in 96.6% of subjects. Maximum rise in heart rate was found in cardiac patients. ST depression was seen in 14.2%, T wave inversion in 13.3%, supraventricular tachycardia in 5.8% and ventricular ectopics in 1.6%. ST depression was more frequent in cardiac than in non cardiac patients (P less than 0.001) and T wave inversion was more frequent in women than in men (P less than 0.001). All the changes reverted to normal within 10 minutes. ECG changes notwithstanding, upper GI endoscopy without premedication in the presence of ambient hypoxia is a safe procedure.


Subject(s)
Altitude , Electrocardiography , Endoscopy, Gastrointestinal , Heart Rate/physiology , Adult , Cardiac Complexes, Premature/diagnosis , Female , Humans , Male , Premedication , Tachycardia, Supraventricular/diagnosis
8.
Indian J Med Res ; 92: 241-5, 1990 Aug.
Article in English | MEDLINE | ID: mdl-2228068

ABSTRACT

Thirty patients of chronic obstructive pulmonary disease (COPD; all smokers) and an equal number of controls (15 smokers) were studied. The COPD patients were further divided into group A (predominantly emphysema) and group B (predominantly bronchitis) of 15 patients each. Serum and sputum IgG, IgA and IgM and serum C3 and C4 were estimated. IgG, IgA, IgM and C3 and C4 were similar in smoker and non-smoker controls. Mean (+/- SD) serum IgG (IU/ml) was significantly higher in COPD patients (207.78 +/- 62.73) than in control (177.25 +/- 43.5; P less than 0.05), serum IgA (IU/ml) was also significantly higher in COPD (205.04 +/- 46.56) than in control (108.21 +/- 33.3; P less than 0.01). IgM was similar in the 2 groups. Sputum IgA (IU/ml) was higher in COPD (4.68 +/- 3.51) than in control (2.25 +/- 1.03; P less than 0.05). IgG and IgM were similar in the 2 groups. Both serum C3 (IU) and C4 (IU) were lower in COPD patients (C3 = 95.9 +/- 33.11, C4 = 113.6 +/- 62.4) than in control (C3 = 167.3 +/- 25.42, C4 = 205 +/- 76.5; P less than 0.05). Serum IgA in type B COPD (212.25 +/- 50.06) was higher than in type A (197.52 +/- 43.3; P less than 0.05) IgG and IgM were similar in these 2 groups. In COPD patients, immunoglobulins were either normal or higher indicating that deficiency of immunoglobulin is not a predisposing factor in development of COPD. Similar immunoglobulin values in smoker and nonsmoker controls indicated that smoking was not the cause of rise of immunoglobulins in COPD.(ABSTRACT TRUNCATED AT 250 WORDS)


Subject(s)
Complement C3/analysis , Complement C4/analysis , Immunoglobulins/analysis , Lung Diseases, Obstructive/immunology , Humans , Immunoglobulin A/analysis , Immunoglobulin G/analysis , Immunoglobulin M/analysis , Smoking/immunology , Sputum/chemistry
14.
Indian Heart J ; 38(2): 134-7, 1986.
Article in English | MEDLINE | ID: mdl-3557506
SELECTION OF CITATIONS
SEARCH DETAIL
...