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Biol Pharm Bull ; 26(7): 1045-8, 2003 Jul.
Article in English | MEDLINE | ID: mdl-12843638

ABSTRACT

Mongolian plants were screened for their influence on alpha-amylase activity in mouse plasma. Methanolic extracts of Geranium pratense, Rhodiola rosea, Ribes pullchelum and Vaccinium uliginosum inhibited the enzyme activity in isolated mouse plasma by greater than 40% and the effect was concentration dependent. Vaccinium uliginosum also showed a depressive effect on elevation of postprandial blood glucose to some extent.


Subject(s)
Gastrointestinal Tract/drug effects , Gastrointestinal Tract/enzymology , Plant Preparations/pharmacology , alpha-Amylases/antagonists & inhibitors , alpha-Amylases/blood , Animals , Drug Evaluation, Preclinical/methods , Male , Mice , Mongolia , Plant Extracts/isolation & purification , Plant Extracts/pharmacology , Plant Preparations/isolation & purification , Plant Structures
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