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J Indian Med Assoc ; 109(6): 428-9, 2011 Jun.
Article in English | MEDLINE | ID: mdl-22315776

ABSTRACT

Diabetes mellitus and hypentension are known to increase markers of inflammation, ie, C-reactive protein (CRP), especially when they develop micro-albuminuria. A total of 60 patients (23 males and 37 females), all having diabetes mellitus, according to ADA criteria and micro-albuminuria in morning spot urine sample were recruited in the study. They were randomised into 2 groups, each comprising 30 patients. Group A comprised hypertensive and Group B normotensive individuals. CRP level was assessed in all patients by routine assay. CRP value of >3 mg/l was observed in 56.66% patients of group A and 23.33% patients of group B (p=0.018). So diabetic patients with micro-albuminuria had more frequent association with increased marker of inflammation in the hypertensive group compared to those without hypertension.


Subject(s)
Albuminuria/diagnosis , Blood Pressure Determination , C-Reactive Protein/metabolism , Diabetes Mellitus, Type 2 , Diabetic Nephropathies/diagnosis , Hypertension , Adult , Age Factors , Albuminuria/metabolism , Albuminuria/physiopathology , Biomarkers , Diabetes Mellitus, Type 2/complications , Diabetes Mellitus, Type 2/metabolism , Diabetes Mellitus, Type 2/physiopathology , Diabetic Nephropathies/metabolism , Diabetic Nephropathies/physiopathology , Early Diagnosis , Female , Humans , Hypertension/complications , Hypertension/metabolism , Hypertension/physiopathology , Inflammation/metabolism , Male , Middle Aged , Risk Factors
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