ABSTRACT
The swine-origin influenza A (H1N1) virus is mainly responsible for flu. No hepatitis attributable to H1N1 virus has been previously documented. Herein, we report on a kidney transplant patient who developed influenza H1N1 virus-induced hepatocellular injury. The patient's body temperature was only somewhat elevated, and pulmonary and flu symptoms were mild. H1N1 virus was detected by polymerase chain reaction assay in nasopharyngeal and bronchoalveolar swabs, as well as in the serum. The hepatocellular injury episode resolved after the patient had been placed on oseltamivir therapy. This observation suggests that acute hepatocellular injury could be linked to the influenza H1N1 virus.
Subject(s)
Hepatitis/pathology , Hepatitis/virology , Influenza A Virus, H1N1 Subtype/pathogenicity , Influenza, Human/complications , Influenza, Human/virology , Kidney Transplantation/adverse effects , Acute Disease , Aged , Antiviral Agents/therapeutic use , Hepatitis/drug therapy , Humans , Influenza A Virus, H1N1 Subtype/isolation & purification , Influenza, Human/drug therapy , Influenza, Human/pathology , Male , Oseltamivir/therapeutic use , Treatment OutcomeABSTRACT
The classical "protective colostomy" upstream of a high risk colo-rectal anastomosis is not fully effective and requires subsequent reconstructive surgery. For these reasons, it is little used to date. Unopened colostomy provides complete obturation above the anastomosis and therefore effective protection. When no anastomotic fistula develops, the colostomy loop is re-entered on the 8th postoperative day. In case of fistula, it is opened and becomes functional. The procedure is easy to perform and well accepted by the patient. It increases surgical safety and shortens the duration of stay in hospital.
