ABSTRACT
Arthro-osteitis is an uncommon condition which can be associated with palmoplantar pustulosis. It forms part of a group of conditions which include the synovitis, acne, pustulosis, hyperostosis, osteitis syndrome (SAPHO) and sternocostoclavicular hyperostosis. We report four cases illustrating the clinical spectrum of this condition which occurred in the absence of concomitant skin lesions. One patient had extensive aortic calcification a feature not previously reported in this condition, which may represent a low grade inflammatory aortitis.
Subject(s)
Hyperostosis, Sternocostoclavicular/pathology , Osteoarthritis/pathology , Rheumatic Diseases/pathology , Sternoclavicular Joint/pathology , Adult , Aged , Female , Humans , Hyperostosis, Sternocostoclavicular/complications , Hyperostosis, Sternocostoclavicular/diagnostic imaging , Male , Psoriasis/complications , Radiography , Rheumatic Diseases/complications , Rheumatic Diseases/diagnostic imaging , Sclerosis , Sternoclavicular Joint/diagnostic imagingABSTRACT
The efficacy and safety of the oral gold compound auranofin and intramuscular gold thiomalate have been compared in a placebo-controlled, double-blind, four-centre trial in 82 patients with psoriatic arthritis requiring remittive drug therapy. There were statistically significant falls in Ritchie articular index, visual analogue pain score and ESR at 12 and 24 weeks following i.m. gold but no significant changes in the auranofin group. Intramuscular gold was safe and more effective than auranofin as a second-line, suppressive antirheumatic agent for patients with psoriatic arthritis when followed for 6 months.
Subject(s)
Arthritis, Psoriatic/drug therapy , Auranofin/therapeutic use , Gold Sodium Thiomalate/therapeutic use , Adult , Arthritis, Psoriatic/blood , Arthritis, Psoriatic/pathology , Blood Sedimentation , Double-Blind Method , Female , Humans , Male , Middle Aged , Multicenter Studies as Topic , Pain , Prospective Studies , Randomized Controlled Trials as TopicABSTRACT
Appendicular bone mass was measured in a series of 50 patients with non-steroid treated rheumatoid arthritis, 20 with polyarticular seronegative psoriatic arthritis, and 30 with osteoarthrosis, and compared with that of 40 controls of similar age and sex. Distal forearm bone mineral content was reduced in patients with rheumatoid and psoriatic arthritis and increased in those with osteoarthrosis. The increase in bone mass in patients with osteoarthrosis was confined to those with isolated large joint disease and was not found in those with primary generalised osteoarthrosis.
Subject(s)
Bone Diseases/metabolism , Bone and Bones/analysis , Joint Diseases/metabolism , Minerals/analysis , Arthritis/metabolism , Arthritis, Rheumatoid/metabolism , Female , Humans , Male , Middle Aged , Psoriasis/metabolismABSTRACT
A 36-year-old man, suffering from psoriatic arthritis from the age of 17 years, was found to have developed atlanto-axial dislocation at the age of 30. Spontaneous fusion took place over the next two years. An explanation for this finding is based upon a review of the literature regarding the nature of spinal involvement in psoriatic arthritis.
Subject(s)
Atlanto-Axial Joint , Joint Dislocations/etiology , Psoriasis/complications , Spondylitis/complications , Adult , Atlanto-Axial Joint/diagnostic imaging , Humans , Male , Radiography , Sacroiliac Joint/diagnostic imaging , Sclerosis/complicationsSubject(s)
Arthritis, Rheumatoid/therapy , Knee Joint , Synovitis/therapy , Humans , Therapeutic IrrigationABSTRACT
In a case of acute Reiter's syndrome with severe vulvitis the diagnosis was based on the presence of a vaginal discharge and dysuria, arthritis, conjunctivitis, buccal ulceration, keratodermia blenorrhagica, and HLA B27 tissue-typing antigen. The vulval lesions were similar in appearance to those of circinate vulvitis. The acute histological change were confined to shallow ulceration with an inflammatory infiltration of the subjacent dermis. Coincidential lichen sclerosus et atrophicus was present, which could have been masked by the acute lesions.
