[Quality of life of patients after phacoemulsification with implantation of trifocal intraocular lens]. / Kachestvo zhizni patsientov posle fakoemul'sifikatsii katarakty s implantatsiei trifokal'noi intraokulyarnoi linzy.

Studying the quality of life (QoL) of patients after multifocal intraocular correction is a relevant problem in the context of intensive development of cataract and presbyopia surgery. PURPOSE: To study the QoL of patients with trifocal and monofocal intraocular lenses 1 year after cataract surgery. MATERIAL AND METHODS: The study included 44 patients divided into two groups: in group 1 - after bilateral implantation of trifocal intraocular lenses, in group 2 - after bilateral implantation of monofocal intraocular lenses. The quality of life of patients in these groups was studied using the VF-14 questionnaire. Additionally, the NAVQ-10 questionnaire was used to study the QoL depending on near vision, satisfaction with the surgery outcome, and the presence and frequency of dysphotopsias. RESULTS: The quality of life of the patients with trifocal intraocular lenses is significantly higher than with monofocal intraocular lenses according to the VF-14 questionnaire (92.61±7.57 in group 1 and 60.96±3.99 in group 2, p<0.001). Using the NAVQ-10 questionnaire, 68.1% of patients with trifocal lenses were found to have no problems with near vision, 82% of them had high satisfaction with the operation result. 4.5% of patients had intensive dysphotopsias in the dark, 41.0% of patients reported light haloes around light sources during the dark hours and night-time, and 54.5% have not reported any dysphotopsias. CONCLUSION: Trifocal intraocular lenses ensure higher quality of life for patients after phacoemulsification when compared with monofocal lenses. Dysphotopsias have some effect on the QoL of patients with multifocal correction, but 82% of them are highly satisfied with the surgery outcome.

[Clinical efficacy of Vitrum Memory in patients with glaucoma and dry form of age-related macular degeneration].

The study was conducted to assess clinical efficacy of Vitrum Memory in therapeutic dosage for 3 months in patients with glaucoma and dry form of age-related macular degeneration (AMD). Survey data, visual acuity, biomicroscopy, computer perimetry, electrophysiological studies (EPS): visual evoked potentials (VEP) and pattern electroretinogram (pattern ERG), HRT-3 and OCT were evaluated. Subjective improvement, reduction of visual and mental fatigue, increase of light sensitivity, as well as statistically significant improvement in visual functions (at both computer perimetry and EPS) were achieved.

[Experimental determination of a safe dose of the enzyme collagenase agent for subconjunctival and retrobulbar administration].

The authors carried out two series of experiments using 32 eyes of 16 rabbits. The enzyme collagenase agent was daily injected, by increasing doses up to 25, 50, 75, and 100 units for subconjunctival ocular (Series 1) and retrobulbar (Series 2) injections. The control groups included 3 rabbits in both series (6 eyes). They were injected 0.5 ml of isotonic sodium chloride solution. It has been concluded that the safest doses of collagemase are 25-50 units for subconjunctival and retrobulbar injection.

[High performance liquid chromatography identification of chloracetophenone in ocular tissues in burns induced by gas balloons (an experimental study)]. / Identifikatsiia khloratsetofenona v tkaniakh glaza pri ozhogakh soderzhimym gazovykh ballonchikov metodom vysokoéffektivnoi zhidkostnoi khromatografii (éksperimental'noe issledovanie).

The kinetics of chloracetophenone (CN) in rabbit eyes was studied by high-performance liquid chromatography on a model of experimental third-degree burn. By the end of the first hour after exposure to the lacrimate, CN content was high in all the studied tissues: 28.5 +/- 0.563 x 10(-1) mg/kg in the cornea, 5.08 +/- 0.193 x 10(-1) mg/kg in the anterior chamber humor, and 3.26 +/- 0.123 x 10(-1) mg/kg in the vitreous. After 6 h the content of the irritant dropped almost threefold and was 8.5 +/- 0.403 x 10(-1) mg/kg in the cornea, 1.23 +/- 0.062 x 10(-1) mg/kg in the anterior chamber humor, and 0.017 +/- 0.006 x 10(-1) mg/kg in the vitreous. By the end of 24 h these values were 6.6 +/- 0.221, 1.46 +/- 0.123, and 0.015 +/- 0.005 x 10(-1) mg/kg, respectively, and by day 14 only trace amounts of CN were detected. Hence, CN in the Cheremukha gas balloons can penetrate into the inner structures of the eye and cause severe injuries. Persistence of CN for up to 14 days disordered the metabolic processes and anatomy of the eye. High content of CN during the first 7 days after burn requires adequate pathogenetic therapy.