ABSTRACT
ABSTRACT: The aim of the present study was to describe the epidemiological and clinical characteristics of inflammatory bowel disease (IBD), including medical and surgical treatments, in several countries in Latin America and the Caribbean.IBD is recognized as a global health problem because its incidence and prevalence have increased significantly over the last few years.This multicenter retrospective cohort study included 4714 patients with IBD diagnosed from 9 countries in Latin America and the Caribbean: Colombia, Cuba, Dominican Republic, Ecuador, Mexico, Peru, Puerto Rico, Uruguay, and Venezuela.Crohn disease (CD) was more frequent in Puerto Rico (71.9%), the Dominican Republic (61.0%), and Peru (53.1%). Ulcerative colitis was more frequent in Colombia (78.6%), Venezuela (78.2%), Mexico (75.5%), Cuba (69.9%), Ecuador (64.1%), and Uruguay (60.9%). The following clinical characteristics were more frequent in the Caribbean: penetrating behavior in CD, steroid dependence, steroid resistance, intolerance to thiopurines, extraintestinal manifestations, surgeries, hospitalizations due to IBD, and family history of IBD. The factors associated with the use of biological therapy were pancolitis in ulcerative colitis, penetrating behavior in CD, steroid resistance and dependence, presence of extraintestinal manifestations, and the need for surgery.This study from Latin America and the Caribbean demonstrated the different epidemiological and clinical characteristics of IBD.
Subject(s)
Colitis, Ulcerative/epidemiology , Crohn Disease/epidemiology , Hospitalization/statistics & numerical data , Inflammatory Bowel Diseases/epidemiology , Adolescent , Adult , Caribbean Region/epidemiology , Chronic Disease , Colitis, Ulcerative/diagnosis , Crohn Disease/diagnosis , Female , Humans , Incidence , Inflammatory Bowel Diseases/diagnosis , Inflammatory Bowel Diseases/therapy , Latin America/epidemiology , Male , Prevalence , Retrospective Studies , Young AdultABSTRACT
Contexto: la enfermedad inflamatoria intestinal (EII) es un proceso inflamatorio crónico del intestino con sus dos variedades, la colitis ulcerativa (CU) y la enfermedad de Crohn (EC). El objetivo del tratamiento es la remisión clínica y endoscópica de la enfermedad, sin embargo, la calidad de vida que esta influye en el manejo y evolución de la enfermedad es usualmente soslayada. Objetivo: determinar la calidad de vida y los factores relacionados en pacientes con EII atendidos en tres hospitales del Seguro Social ecuatoriano. Metodología: estudio observacional, descriptivo y transversal en pacientes mayores de 18 años diagnosticados de EII, que acuden al servicio de gastroenterología de tres hospitales del Seguro Social: Carlos Andrade Marín, José Carrasco Arteaga y Teodoro Maldonado, en el periodo enero a junio de 2018. Resultados: se evaluaron 50 pacientes, 68% (n=34) con CU y 32% (n=16) con EC. La edad promedio fue 48 +/-9 para CU y 42+/-7 en EC. Se determinó una relación hombre: mujer de 1,6:1. El 30% de los pacientes evaluados (n=15) percibieron su calidad de vida como baja. Se encontró diferencias estadísticamente significativa en relación al tipo de EII (EC, p 0,03), sexo femenino (p 0,04) y presencia de recaídas (p 0,04). Conclusión: la calidad de vida en los pacientes con enfermedad inflamatoria intestinal fue percibida como más baja en pacientes de sexo femenino que quienes padecen EC y en quienes presentan uno o más episodios de recaídas durante el último semestre.
Background: Inflammatory bowel disease (IBD) is a chronic inflammatory process of the intestine with its two varieties, ulcerative colitis and Crohn's. The goal of treatment is the clinical and endoscopic remission of the disease. However, the quality of life that influences the management and evolution of the disease is usually overlooked. Aim: To determine the quality of life and related factors in patients with IBD treated in three hospitals of Ecuadorian Social Security. Methods: Epidemiological, observational, descriptive and cross-sectional study in patients over 18 years of age diagnosed with IBD, who attend the gastroenterology service of three hospitals: Carlos Andrade Marin, Jose Carrasco Arteaga and Teodoro Maldonado, in the period January to June 2018. Results: 50 patients were evaluated, 68% (n=34) with UC and 32% (n=16) with CD. The average age was 48 +/- 9 years for CU and 42+/- 7 years in CD. A male female ratio of 1.6: 1 was determined. 30% of the patients evaluated (n=15) perceived their quality of life as low. Statistically significant differences were found in relation to the type of IBD (CD, p 0.03), female sex (p 0.04) and the presence of relapses (p 0.04). Conclusions: The quality of life in patients with inflammatory bowel disease was perceived as lower in female patients than those with CD and in those with one or more relapse episodes during the last semester.
