Subject(s)
Breast Neoplasms/pathology , Choroid Plexus Neoplasms/diagnostic imaging , Choroid Plexus Neoplasms/secondary , Multimodal Imaging , Positron-Emission Tomography , Retinal Detachment/diagnostic imaging , Sarcoidosis/diagnostic imaging , Tomography, X-Ray Computed , Biopsy , Female , Humans , Magnetic Resonance Imaging , Middle AgedABSTRACT
PURPOSE: To retrospectively analyze whether adding a delayed high-resolution dedicated neck F-18 FDG positron emission tomography-computerized tomographic (PET-CT) imaging protocol in patients with recurrent differentiated thyroid cancer increases the number of abnormal foci within the neck. MATERIALS AND METHODS: Seventeen PET-CT studies from a total of 10 patients with suspected recurrent differentiated thyroid cancer between March 2003 and June 2004 were retrospectively reviewed. Each study included a whole body acquisition (WBA), followed by higher resolution dedicated neck acquisition (DNA). Two board-certified nuclear medicine physicians reviewed either the DNA or WBA for each study and recorded the number of abnormal foci, along with presence or absence of a soft tissue abnormality, and maximum standardized uptake value for each foci. Consensus review was used for all discrepancies. Statistical analysis was performed to determine whether there was a statistically significant increase in the number of studies demonstrating new abnormal foci with the addition of a DNA. RESULTS: Five of 17 studies demonstrated an increase in the number of abnormal foci with the addition of the DNA (P < 0.04). A total of 8 abnormal foci were noted on the WBA, 4 of which were within the neck. Eleven additional abnormal foci were seen on the DNA. All abnormal foci within the neck had corresponding soft tissue abnormalities except for one. CONCLUSION: Adding a higher resolution delayed DNA to the WBA for patients undergoing PET-CT imaging to detect recurrent thyroid cancer increases the number of abnormal sites of FDG accumulation.
Subject(s)
Carcinoma/diagnosis , Carcinoma/pathology , Fluorodeoxyglucose F18/pharmacology , Positron-Emission Tomography/methods , Radiopharmaceuticals/pharmacology , Thyroid Neoplasms/diagnosis , Thyroid Neoplasms/pathology , Tomography, X-Ray Computed/methods , Carcinoma/diagnostic imaging , Cell Differentiation , Contrast Media/pharmacology , DNA/chemistry , Humans , Neck/diagnostic imaging , Neck/pathology , Neoplasm Recurrence, Local/diagnostic imaging , Neoplasm Recurrence, Local/pathology , Recurrence , Retrospective Studies , Thyroid Neoplasms/diagnostic imaging , Whole Body ImagingABSTRACT
A 27-year-old white man was diagnosed with a testicular, metastatic germ cell tumor. The patient was evaluated with F-18 fluorodeoxyglucose positron emission tomography and coregistered computed tomography (FDG PET/CT) as well as a contrast-enhanced CT (CECT) of the abdomen and pelvis. Serologic tests were performed. At laparoscopic appendectomy, findings were consistent with acute suppurative appendicitis. This case exemplifies the relevance of incidental findings detected on FDG PET/CT.
