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1.
Contemp Clin Trials ; 141: 107533, 2024 06.
Article in English | MEDLINE | ID: mdl-38621517

ABSTRACT

BACKGROUND: Midlife hypertension is associated with cognitive decline and Alzheimer's disease and related dementia (ADRD), suggesting that blood pressure control may be a therapeutic target for dementia prevention. Given excess hypertension in non-Hispanic Black (NHB) adults, blood pressure control may also reduce ADRD disparities. We describe a pilot randomized controlled trial (RCT) to evaluate the feasibility and preliminary efficacy of a multicomponent lifestyle-based intervention versus enhanced usual care on cognition among middle-aged NHB adults. METHODS AND STUDY DESIGN: The Food Resources and Kitchen Skills plus Aerobic Training (FoRKS+) study is a 2-arm, single-blinded trial that compares those receiving the FoRKS+ program (target N = 64) versus those receiving enhanced usual care (target N = 64) in local federally-qualified health centers. Key eligibility criteria include self-identified NHB adults between ages 35-75 with a mean systolic blood pressure ≥ 130 mm/Hg obtained from 24-h ambulatory blood pressure monitoring. The FoRKS+ program includes 5 weeks of hypertension self-management courses, 11 weeks of nutrition courses, and 12 weeks of aerobic training in dietitian and health coach-led virtual groups. We will collect data on primary cognitive outcomes, feasibility, hypothesized intervention mediators and moderators, and demographic and health covariates at baseline, near intervention weeks 16-, and 28 (primary outcome assessment), and week 52 follow-up. We will use mixed-effects modeling to examine intervention effects on cognition. DISCUSSION: This pilot RCT will examine the feasibility and preliminary effects of a multicomponent lifestyle intervention on cognitive function in NHB adults, which may have implications for reducing health disparities in ADRD.


Subject(s)
Black or African American , Hypertension , Humans , Hypertension/therapy , Middle Aged , Pilot Projects , Aged , Single-Blind Method , Adult , Female , Male , Exercise , Cooking/methods , Blood Pressure , Life Style
2.
Nutrients ; 15(6)2023 Mar 17.
Article in English | MEDLINE | ID: mdl-36986184

ABSTRACT

Food insecurity affects nearly 50 million Americans and is linked to cardiovascular disease risk factors and health disparities. The purpose of this single-arm pilot study was to determine the feasibility of a 16-week dietitian-led lifestyle intervention to concurrently address food access, nutrition literacy, cooking skills, and hypertension among safety-net primary care adult patients. The Food Resources and Kitchen Skills (FoRKS) intervention provided nutrition education and support for hypertension self-management, group kitchen skills and cooking classes from a health center teaching kitchen, medically tailored home-delivered meals and meal kits, and a kitchen toolkit. Feasibility and process measures included class attendance rates and satisfaction and social support and self-efficacy toward healthy food behaviors. Outcome measures included food security, blood pressure, diet quality, and weight. Participants (n = 13) were on average {mean (SD)} aged 58.9 ± 4.5 years, 10 were female, and 12 were Black or African American. Attendance averaged 19 of 22 (87.1%) classes and satisfaction was rated as high. Food self-efficacy and food security improved, and blood pressure and weight declined. FoRKS is a promising intervention that warrants further evaluation for its potential to reduce cardiovascular disease risk factors among adults with food insecurity and hypertension.


Subject(s)
Cardiovascular Diseases , Hypertension , Humans , Adult , Female , Male , Pilot Projects , Hypertension/epidemiology , Hypertension/prevention & control , Meals , Food Insecurity
3.
J Clin Hypertens (Greenwich) ; 22(11): 2146-2151, 2020 11.
Article in English | MEDLINE | ID: mdl-32882098

ABSTRACT

Hypertension continues to be a health crisis, with multiple approaches attempting to define best practices for management. The objective of our hypertension group education program is to improve patient health outcomes through engaging a multidisciplinary health professional team. A 6-hour group curriculum was created with a focus on nutrition, lifestyle, and medication approaches to hypertension management, while incorporating personally identified behavior change goals and barriers. Outcomes were tracked pre-program, at program completion, and 6 and 12 months post-program completion. Program participants demonstrated immediate and sustained improvements in blood pressure readings and attainment of personal behavior change goals. Group hypertension education classes are an effective way to care for patients. Additional healthcare resources should be dedicated to creating and evaluating educational delivery models that are sustainable and provide results over time, including financial implications to the health system.


Subject(s)
Hypertension , Blood Pressure , Curriculum , Health Education , Humans , Hypertension/prevention & control , Life Style
4.
Appl Physiol Nutr Metab ; 43(12): 1326-1333, 2018 Dec.
Article in English | MEDLINE | ID: mdl-29894642

ABSTRACT

We investigated the influence of immediate postexercise dietary supplementation on the subsequent food consumption pattern and endurance exercise performance in physically trained individuals. On 2 occasions, trained male cyclists performed a glycogen-depleting exercise bout followed by a 2-h nutritional supplementation period, 28 h of free-living recovery, and a subsequent 40-km cycling time trial. During the 2-h postexercise supplementation, the subjects consumed equal volumes of reduced-fat chocolate milk (CM) or a sports beverage (SB) in a single-blind, randomized design. Thereafter, the cyclists maintained a food log during the free-living recovery period. Dietary and exercise performance parameters were compared between the treatment beverage visits. No differences in total caloric and macronutrient intakes were detected between the CM and SB trials over the course of the free-living recovery. However, a significant interaction (treatment × time) was detected for caloric and macronutrient intakes during the early phase of free-living recovery, such that significantly larger proportions were consumed shortly after SB as compared with CM. No difference was observed in completion time of the 40-km cycling time trial (CM: 66.9 ± 4.1 vs SB: 66.9 ± 3.7 min). Hence, the cyclists achieved similar levels of recovery during the prolonged, free-living period despite the different acute, postexercise nutrient intake rates. We suggest that given adequate time, athletes appear to subconsciously modify their food consumption in response to varied postexercise supplementation such that subsequent-day exercise performance is equivalent.


Subject(s)
Bicycling/physiology , Eating/physiology , Feeding Behavior/physiology , Glycogen/metabolism , Physical Endurance/physiology , Adult , Animals , Chocolate , Dietary Carbohydrates , Energy Intake/physiology , Humans , Male , Milk , Young Adult
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